8kPa, 113 cases of type ASD and VSD with diameter from 0.5 to 2.0 cm were operated upon with open heart technic from June 1995 to June 1999. There was no mortality, no air embolism, except in 4 cases operation was only completed under moderate hyperthermia and cardiac arrest instead due to poor vision of the operating field. 12 cases were complicated by slight hemoglubinuria after 24h of operation, and 1 case by remnant VSD. 95 cases were followed up, and they were in healthy condition. This operative technic is suitable for the repair of secondary ASD, and small or moderate, membranous or para membranous VSD. Its advantage is less myocardial damage, and shorten the duration of cardiac arrest. Air embolism is likely to take place by using this method, but effective method should be taken to prevent it.

Objective: To study the effect and mechanism of delayed preconditioning induced by adenosine A 1 receptor. Methods: Male Wistar rats in group A, C,D,K were preconditioned with CCPA, normal salt, Pyrrolidin diethyldi thiocarbamate(DDTC), DDTC +CCPA, respectively. The hearts were isolated and perfused with H-K buffer solution on the Langendorff apparatus 24 hours later,the isolate heart was perfused modified St.Thomas solution for 180 minutes at 4℃, and then reperfused with the H-K buffer for 60 minutes at 37℃. Results:The left ventricular function (+dp/dt max ,%) and myocardial ATP level in group A were better than those of C, D, K groups (P

Objective To discuss the experience of open heart operation on beating in complex and severe congenital heart diseases. Method This kind of operation was put to use in 48 cases of the heart diseases in order to observe the effect of myocardial protection, prevention from air embolism,exposure of the operative field, and cardiopulmonary bypass. Results Operation field exposure was clear enough to finish the manipulation. One cases was eventiful postoperatively and died(2.08%). Conclusion Open heart operation on beating with slight hypothermia might have much feasibility in the part of complicated and severe congenital heart diseases.