Objective To explore the distribution of vascular lesions in the cerebral digital subtraction angi-ography( DSA) and associated diseases in patients with ischemic cerebrovascular disease( ICVD) ,and complications, as well as the value of DSA in ICVD.Methods The DSA data of 99 ICVD cases were analyzed retrospectively, patients treated by ischemia type were divided into the cerebral infarction(CI) and transient ischemic attack(TIA) group.All patients were examined by 3D-TOF and neck vascular ultrasound screening,the final diagnosis by DSA. While observing the perioperative complications and associated diseases.Results 99 patients with ICVD,88 cases of the presence of vascular lesions diagnosed by DSA.In 99 cases,there were 252 lesions,accounting for the top three for the internal carotid artery(ICA),vertebral artery(VA) and the middle cerebral artery(MCA).While there were 121 bifurcation lesions,accounting for the top three for ICA,VA,and the external carotid artery(ECA).TIA in patients with concomitant diseases accounted for the top three for hypertension(HTN),type 2 diabetes mellitus(T2DM) and hyperlipidemia and renal insufficiency;Patients with CI associated diseases accounted for the top three for HTN, T2DM and hyperlipidemia.There were 10 cases of patients with DSA complications,most of the vasovagal reflex in five cases;serious for TIA and CI in 1 case ( not cause any neurological deficits at discharge ) .Conclusion Carotid vascular disease plays an important role in the occurrence of ICVD, especially in the blood vessels of bifurcation lesion.Within ICVD risk factors in HTN in the majority, followed by T2DM, hyperlipidemia.DSA surgery rarely serious complications,blood vessels can provide more comprehensive information,and provide the basis for further development of ICVD prevention and treatment programs,this checking method is safe and reliable.