No abstract available.
Diabetic Neuropathies*

No abstract available.
Diabetic Neuropathies*

No abstract available.
Diabetic Neuropathies ; Humans

No abstract available.
Diabetic Neuropathies ; Humans

BACKGROUND AND OBJECTIVES: It is important to adequately estimate the functional handicap of the patient with polyneuropathy. Computerized dynamic posturography (CDP) can be utilized in those patients to evaluate balance performance. But, so far, the majority of data are about sensory organization test (SOT) and the efficacy of motor control test (MCT) is not established. We performed this study in an attempt to estimate balance function in diabetic neuropathy patients using MCT, thereby confirm the usefulness of MCT in evaluating balance ability. SUBJECTS AND METHODS: Seventeen diabetic neuropathy patients (DM-NP), 9 non-neuropathy diabetic patients (DM-nonNP), and 22 non-diabetic normal persons as controls (nonDM) were included in this study. Postural responses to horizontal translation were assessed according to the MCT paradigm. The results were compared with the sway energy obtained during toes-up or toes-down perturbation. RESULTS: Latencies of backward translation were prolonged in DM-NP but not in DM-nonNP. Latencies of forward translation were prolonged both in DM-NP and DM-nonNP. No definite correlation could be drawn between the MCT and EMG latencies. DM-NP showed increased sway energy in toes-up and toes-down perturbation. MCT latencies and sway energy in perturbation showed significant correlation. CONCLUSION: MCT proved to be useful in evaluating balance performance in the patients with defective postural response as in diabetic neuropathy.
Diabetic Neuropathies ; Humans ; Polyneuropathies

No abstract available.
Diabetic Neuropathies* ; Neural Conduction*

No abstract available.
Diabetic Neuropathies* ; Neural Conduction*

This article provides an overview for understanding the classification and pathogenesis of diabetic neuropathy. Diabetic neuropathies are prevalent disorder. The most common manifestation is distal symmetric polyneuropathy, but various patterns of neuropathy can occur. New information for the pathogenesis of diabetic neuropathy continues to emerge, which will lead to identifying new drug targets.
Classification ; Diabetic Neuropathies ; Polyneuropathies

Introduction: Diabetes Mellitus is a chronic non-communicable disease that has been increasing in prevalence worldwide. Preventing and treating diabetes and its complications have been a burden in the health care system. Diabetic neuropathy is its frequent complication and in the long run, is associated with a negative impact on the functioning and quality of life. Hence, its early detection can prevent and delay its sequelae and improve patients’ quality of life. Objective: To determine the prevalence and burden of neuropathy among diabetic patients of Eastern Visayas Regional Medical Center (EVRMC) Family Medicine Diabetes Wellness Clinic Methods: This was an analytical cross-sectional study. Patients at the EVRMC Family Medicine Diabetes Wellness Clinic from May to October 2020 were included. The Michigan Neuropathy Screening Instrument was used to diagnose diabetic neuropathy. Descriptive statistics, Chi-square test, and Fisher’s exact test were used to determine the association between socio-demographic profile and clinical characteristics among neuropathic patients. Results: Two hundred ten patients were enrolled. Majority were female (66.7%), ≥60 years old (58.1%), with vocational/college degrees (37.1%), unemployed (75.2%), did not have glycemic control (80%), had diabetes for ≤5 years (57.1%), and took two maintenance medications (46.7%). Biguanide was the most common maintenance drug (70.5%). Among diabetic patients, 30.5% had neuropathy. Statistically significant associations were seen in ≥60 years old [OR 1.92, p=0.04], with vocational/ college degrees [OR 2.17, p=0.01], and with diabetes for 6-10 years [OR 2.42, p=0.01] and ≥20 years [OR 5.07, p=0.01. Conclusion Diabetes Mellitus was prevalent in elderly age group, female gender, with vocational/college degrees, and unemployed. Most had uncontrolled sugar, had diabetes for ≤5 years, and took two maintenance drugs. Only 30.5% had neuropathy. Diabetic patients ≥60 years old, had vocational/college degrees, and had longer duration of the disease had higher odds of having diabetic neuropathy.
Diabetes Mellitus ; Diabetic Neuropathies

Objective: This study aims to determine the association of serum magnesium with distal symmetric peripheral neuropathy among persons with type 2 diabetes mellitus (DM). Methodology: A cross-sectional analytical study among adult Filipinos with Type 2 DM. Logistic regression was used to determine the association of serum magnesium with DSPN diagnosed by the Michigan Neuropathy Screening Instrument. The null hypothesis was rejected at 0.05α-level of significance. Results: The average serum magnesium levels were similar between those with versus without DSPN (2.06 ± 0.32 vs 2.05 ± 0.23, p = 0.873); the same was seen for corrected magnesium. There is insufficient evidence to demonstrate a significant statistical difference between those with and without DSPN in relation to glycemic control (HbA1c and FBS). Likewise, there is no significant statistical correlation between serum magnesium levels with HbA1c, FBS, BMI, or duration of diabetes. Conclusion This present study could not demonstrate any association between DSPN and serum magnesium, even after adjusting for age, sex, and comorbidity.
Magnesium ; Diabetic Neuropathies