1.Progress in Endoscopic Treatment of Benign Anastomotic Stenosis after Esophagogastrectomy
Min ZHAO ; Naning SHEN ; Jing AI ; Di CHEN ; Hongbo ZHANG
Chinese Journal of Gastroenterology 2017;22(4):253-256
Benign anastomotic stenosis after esophagogastrectomy could reduce the patients' quality of life,even resulting in severe malnutrition and death.The endoscopic treatment includes dilatation,stent insertion,locoregional injection,and a relatively new technique radial incision and cutting.This article reviewed the progress in endoscopic treatment of benign anastomotic stenosis after esophagogastrectomy.
2.Metastatic adrenal carcinoma
Qingyou ZHENG ; Xianyou XU ; Guiping DI ; Guohui ZHANG ; Xing AI
Chinese Journal of Urology 2010;31(12):803-805
Objective To discuss the diagnosis and management of metastatic adrenal carcinoma. Methods Forty-seven cases with metastatic tumor in the adrenal glands were analyzed retrospectively from December 1996 to April 2010. Lung was the most common primary tumor site (51.1 %, 24 cases), followed by the renal cell carcinoma (12.8%, 6 cases), liver cancer (10.6%,5 cases), breast cancer (8.5%, 4 cases), melanoma (4.2%, 2 cases), and other carcinoma (12.8%,6 cases). Most patients with metastatic adrenal carcinoma had no special clinic manifestation. Lesions of 36 cases were surgically removed and 11 cases gave up operation. Results The mean survival time were 33.8±4.5 months for 31 cases underwent adrenalectomy and 6.3±2.7 months for 6 cases without operation. Patients with surgically removed adrenal metastases had better survival than those without surgical resection. Conclusions Adrenal gland is a common site of metastatic carcinoma.Ultrasonographic and CT scans are important diagnosis methods for metastatic adrenal carcinoma. Operation is still effective and long-term survival may be achieved for those well selected patients, but surgical indication must be strictly monitored.
4.Sarcomatoid carcinoma in urinary bladder: report of a case.
Ai-jing SUN ; Li-ping SUN ; Di-lai HUANG
Chinese Journal of Pathology 2009;38(3):203-204
Aged
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Antibodies, Monoclonal
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metabolism
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Carcinoma, Transitional Cell
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metabolism
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pathology
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surgery
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Cystectomy
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Follow-Up Studies
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Humans
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Keratin-7
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metabolism
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Keratins
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immunology
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Lung Neoplasms
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secondary
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Male
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Urinary Bladder Neoplasms
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metabolism
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pathology
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surgery
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Vimentin
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metabolism
5. Absorbable suture anchors for treating femoroacetabular impingement syndrome combined with acetabular labral tears
Chinese Journal of Tissue Engineering Research 2020;24(4):499-504
BACKGROUND: Metal anchors are not easily accepted by patients as permanent foreign bodies, so bioabsorbable anchors have been gradually applied in orthopedics in recent years. OBJECTIVE: To evaluate the effectiveness of absorbable suture anchors for repairing femoroacetabular impingement syndrome combined with acetabular labral tears. METHODS: Eighty patients with femoroacetabular impingement syndrome combined with acetabular labral tears admitted in Beijing Shijitan Hospital Affiliated to Capital Medical University from February 2014 to February 2016 were selected, and all were treated by absorbable suture anchors under arthroscopy. The Harris hip score, and the Visual Analogue Scale score at baseline, postoperative 1 and 3 months were recorded and compared to assess the effectiveness. The complications and material-host reaction were recorded. The treatment satisfaction was evaluated. The study was approved by the Ethical Committee of Beijing Shijitan Hospital and all patients and their families signed the informed consents. RESULTS AND CONCLUSION: (1) The Harris hip scores at 1 and 3 years postoperatively in 80 patients with femoroacetabular impingement syndrome combined with acetabular labral tears were significantly higher than those at baseline, and the Visual Analogue Scale scores were significantly lower than those at baseline (P < 0. 05). (2) The excellent and good rate of treatment in patients at 1 and 3 years was 90. 0% and 97. 50%, respectively, and the treatment satisfaction was 87. 4% and 93. 8%, respectively. The excellent and good rate of treatment and treatment satisfaction presented an increased trend with time, but had no significant difference (P > 0. 05). (3) None appeared with anchor drop off, cartilage injury or material-host reaction. In summary, the method of absorbable suture anchors under arthroscopy has the advantages of minimal invasion, reliable fixation, simple operation, no metal implants, and significant clinical effect to treat femoroacetabular impingement syndrome combined with acetabular labral tears.
6.Researching on fingerprint of Inulacappa by HPLC.
Di-fei-fei XIONG ; Di ZHU ; Dan TAN ; Yan-yu LAN ; Lin ZHENG ; Ai-min WANG
China Journal of Chinese Materia Medica 2015;40(3):480-483
OBJECTIVEThis study is to establish the fingerprint and find out the common chromatographic peaks of Inula cappa by HPLC.
METHODThe HPLC analysis was performed on an Agilent Eclipse Plus C18 column (2.1 mm x 150 mm, 1.8 μm) with 0.1% fomic acid aqueous solution-0.1% fomic acid acetonitrile solution as mobile phase at a flow rate of 0.3 · mL(-1) · min(-1); The detective wavelength is 325 nm; The column temperature is 45 °C.
RESULTThe results indicated that 5 of 17 common peaks were identified . The similarity about 10 groups of Inulacappais is over 0.95.
CONCLUSIONThis method is able to be a scientific basis of quality assessment according to its convenient and reliable.
Chromatography, High Pressure Liquid ; methods ; Drugs, Chinese Herbal ; analysis ; Inula ; chemistry
7.Anti-oxidant Effect of Gastrodin in Epilepsy Rats
Lianmei ZHONG ; Yong BAI ; Qinglong AI ; Di LU ; Yanfang WU ; Ligong BIAN ; Jiazhi GUO ; Zhirong ZOU
Journal of Kunming Medical University 2016;37(6):5-8
Objective To explo the antioxidant effect and molecular mechanism of gastrodin (Gas) in epilepsy (EP) rats induced by LiCl-pilocarpine (PILO) . Methods Eighty male SD rats were randomly divided into 5 groups: sham group, EP group, therapy groups (pretreated with 60 mg/kg, 90 mg/kg, 120 mg/kg of gastrodin respectively) . The EP model was esteblished by peritoneal injection of LiCl-PILO. Therapy groups were pretreated with various concerntration of Gas. The control group was given the same dosage of normal saline. The alteration of behavior was observed, the concentration of catalase (CAT), glutathion (GSH), superoxide dismutase (SOD), glutathion reductase (GR), total antioxidtion (T-AOC) and malondialdehyde (MDA) in rats brain cortex were detected by chemical colorimetric method, phosphorylation of p38 was determined by western blot. Results There was no EP seizure in sham group,and the EP seizure degree in therapy groups (gas pretreated groups) was significantly decreased,and had statistically significant difference with EP group (P<0.05) . The EP model rats exhibited a significant decrease in the concentration of endogenous antioxidants (CAT, GSH, SOD, GR and T-AOC), while an increase of the concentration of MDA and phosphorylation p38 protein as compared to sham group (P<0.05) . After treatment of the Gas,treatment group rats attenuated the seizure degree,exhibited a significant increase of the concentration of endogenous antioxidants (P<0.05),while a decrease in concentration of MDA and phosphorylation of p38 as compared to model group (P<0.05) . Conclusion Gas may have a neuroprotective role in central nervous system of epileptic rats modle by down-regulateing the seizure degree and the activity of p38 kinase and up-regulateing the content of endogenous antioxidants.
8.The Activation and Polarization of Microglia in Epileptic Rats Induced by Pilocarpine
Lianmei ZHONG ; Qinglong AI ; Jiazhi GUO ; Jun SUN ; Di LU ; Yanfang WU ; Ligong BIAN ; Zhirong ZOU
Journal of Kunming Medical University 2016;37(5):1-4
Objective To explore the activition and polarization of microglia in the epileptic rats induced by lithium chloride-pilocarpine. Methods One hundred male SD rats were randomly divided into five groups: control group and different time points model groups including 1d,3d,7d and 14d. Epilepsy models were established by lithium chloride-pilocarpine intraperitoneal injection. The control group was given the same dosage of normal saline. The morphology change was detected by immunofluorescence,and the expressions of iNOS and Arg-1 were determined by IHC at respective time points. Results Compared the model groups with control group,microglia was activated,synapsis was shorten,volume got bigger,most of them seemed as amoebocyte,the expression of iNOS increased and Arg-1 decreased,especially at 3d.ConclusionThe results from this study indicated that microglia was activated and polarized in epileptic rats induced by pilocarpine.
9.Primary thymic adenocarcinoma: report of a case.
Song-mei LI ; Zhi-qiang WANG ; Hai-ping WANG ; Ai-di ZHOU
Chinese Journal of Pathology 2012;41(9):639-640
Adenocarcinoma
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diagnostic imaging
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metabolism
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pathology
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surgery
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Carcinoembryonic Antigen
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metabolism
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Diagnosis, Differential
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Follow-Up Studies
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Humans
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Keratin-20
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metabolism
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Male
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Microfilament Proteins
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metabolism
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Middle Aged
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Phosphopyruvate Hydratase
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metabolism
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Thymus Neoplasms
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diagnostic imaging
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metabolism
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pathology
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surgery
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Tomography, X-Ray Computed
10.Effect of fuzheng jianpi recipe on content of trace element and immune function in children with spleen deficiency anorexia.
Chinese Journal of Integrated Traditional and Western Medicine 2002;22(6):429-431
OBJECTIVETo evaluate the efficacy and prospect of Fuzheng Jianpi Recipe (FZJPR) in treating children's Spleen deficiency anorexia (CSDA) by means of observing its effect on trace element content and immune function.
METHODSOne hundred and thirty cases of CSDA were treated with FZJPR, one dose per day in decoction, orally taken, 30 days for one therapeutic course. Levels of T-lymphocyte subsets, IL-2R, immunoglobulin and trace elements were determined before and after treatment, and compared with those in the control group consisted of 60 healthy children.
RESULTSIn the treated group, abnormal figures were shown in T-lymphocyte subsets, especially in lowering of CD3 and CD4 count before treatment, and IgG content was reduced also. After treatment, CD3, CD4, CD4/CD8 ratio as well as IgG and IgA were improved significantly (P < 0.01), IL-2R percentage approached normal. Moreover, the levels of Zn and Fe changed significantly (P < 0.01).
CONCLUSIONFZJPR could improve the trace elements content and immune function in CSDA children, so it is effective in treating CSDA.
Anorexia ; blood ; drug therapy ; immunology ; Child ; Child, Preschool ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Humans ; Immunoglobulin G ; blood ; Male ; Phytotherapy ; Receptors, Interleukin-2 ; blood ; T-Lymphocyte Subsets ; drug effects ; Trace Elements ; blood ; Yang Deficiency ; blood ; drug therapy ; immunology