1.ANALYSIS OF MAJOR PROTEINS OF THE TWELVE STANDARD SEROVARS AND SIX LOCAL ISOLATES OF UREAPLASMA UREALYTICUM
Yuankang YE ; Changhong YIN ; Yueye WANG ; Deyuan LU ;
Microbiology 1992;0(05):-
More than 20 protein bands with molecular weights of 19—175 KD in 18 strains of Ureaplosma urealyticum were detected by SDS-PAGE and thin layer scanning analysis. The molecular weights of major proteins were between 32 KD and 140 KD. Among them, the percentages of 67, 78 and 140 KD proteins were similar in all strains, but those of 32, 43 and 94 KD proteins were greatly different. Thus, Ureaplasma urealyticum can be divided into two groups: group A including serovars 2,5,7,9,10,11,12, and local isolates C,D, E, F; group B including serovars 1,3,6,13,14, and local isolates A, B. The serovars of Ureaplasma urealyticum could not be distinguished by using SDS-PAGE alone.
2.Clinical evidence for immunologic treatment in newborn infants with sepsis
Zhongqiang LIU ; Xihong LI ; Deyuan LI ; Lili LUO ; Guoyan LU ; Dezhi MU
Chinese Journal of Applied Clinical Pediatrics 2015;30(6):429-432
Objective Neonatal sepsis (NS) is one of the main causes of neonatal death.Immune therapy is an important way in the comprehensive treatment of NS.This study investigated several databases in order to find the clinical evidence for the immunological treatment of neonatal sepsis (NS),and to explore its clinical application value.Methods Systematic reviews and randomized (or quasi-randomized) controlled trials (RCT) for immunological treatment of NS in newborn infants were searched from the databases of MEDLINE,EMBASE and Cochrane Library.The relevant literatures were statistically analyzed.Results Six systematic reviews (including 37 RCTs) were found to be involved in the therapy,and the drugs included intravenous immunoglobulin (containing high level of IgM),antistaphylococcal immunoglobulins,neutrophile granulocyte,granulocyte colony-stimulating factor,granulocyte-macrophage colony-stimulating factor,pentoxifylline and glutamine.Pentoxifylline could decrease the mortality (Z =2.71,P =0.006 8),shorten the hospitalization (Z =2.01,P =0.044),and reduce the incidence rate of necrotizing enterocolitis (NEC) (Z =1.67,P =0.095) of the NS infants.No therapeutic effect was found for other drugs in the treatment of NS.Conclusions Current clinical evidence for the immunological treatment of NS indicates that only Pentoxifylline could decrease the mortality,reduce the incidence rate of NEC and shorten the hospitalization of infants with NS.However,current evidence is only a small scale sampling and lacks multicenter studies.Researchers are encouraged to undertake large scale and well-designed multicenter trials to confirm the effectiveness of the immunological treatment of NS.
3.Prevalence of palmar hyperhidrosis and mental health status analysis among 25 680 soldiers
Lihuan ZHU ; Zhaotong LU ; Xingqiang WANG ; Shujian PAN ; Xianwu XU ; Tao LI ; Deyuan ZHAO
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(3):265-267
Objective To investigate palmar hyperhidrosis (PH) and the effects on mental health in a military command.Methods 26 392 soldiers were enrolled in this study by stratified-cluster random sampling.Each was required to complete a self-administered questionnaire regarding PH.The soldiers were assessed with symptom checklist-90 (SCL-90) and the factor scores were compared with army norm and civilian norm.Results A total of 25680 subjects fulfilled the questionnaires,and the response rate was 97.3%.The prevalence of PH in the survey sample was 2.66% and the mild,moderate,and severe PH were 1.49%,0.83%,and 0.34%,respectively.The total mean score of SCL-90 in soldiers with PH (1.72±0.54) was higher than those none PH soldiers (1.65±0.58),civilian norm (1.49±0.41) and military norm (1.63±0.30).Multiple regression analysis showed that age,level of education and severity of PH were important factors for mental health of soldiers with PH (P<0.05).Conclusion PH is more common in the military,which affect the mental health.The health service departments should pay attention to the treatment and psychological intervention of PH.