1.Observation on Clinical Therapeutic Effect of Zhenerkang for Children with Hypoferric Anemia and Physique Dysplasia
China Pharmacy 1991;0(06):-
The clinical therapeutic effects of Zhenerkang for 99 cases of children with hypoferric anemia and physique dysplasia were studied in present paper. For the anemia children two mouths of treatment made the Hb content raise by an average of 21.60g/L and the blood concentrations of metallic elements such as Fe,Ca,Zn,Cu,Se,Ge,etc elevate obviously. The drug was more effective for children with hypoferric anemia as compared with the control (Pearl powder).
2.Molluscicidal effect of niclosamide ethanolamine salt powder - granula against Oncomelania hupensis
Benrong YOU ; Yixin HUANG ; Hengguang HU ; Derong HANG ; Shibao JING ; Qiaofang MEI
Chinese Journal of Schistosomiasis Control 2016;28(3):237-240,326
Objective To evaluate the molluscicidal effect of niclosamide ethanolamine salt powder?granula(PG)against Oncomelania hupensis. Methods The molluscicidal experiment was carried out by the dusting method with niclosamide etha?nolamine salt 4%PG. The experiments were respectively done in the laboratory and the tidal flats wetlands. At the same time , the niclosamide ethanolamine salt 4%dustable powder(DP)was as the control group. The single blind method was used for the quality control. The corrected mortality and the median lethal concentration(LC50)were compared between PG and DP in the molluscicidal experiment of the laboratory. The corrected mortality and the reduced rate of snails’density were compared be?tween PG and DP in the tidal flats wetlands. Results The mortality rates of the snails were 96.67%and 100%respectively on 1 d after dusting 4.0 g/m2 of 4% PG and 2.0 g/m2 of 4% DP in the laboratory. The results showed that the mortality rates of the snails were higher with 4%DP than 4%PG in each dosage(t1 d=3.60,P<0.01). The LC50(s) of 1d,3 d,7 d after dusting the molluscicide also showed that the molluscicidal effects of DP were better than PG. The corrected mortality rates were 91.71%, 92.91%,90.57%,85.33%and 71.09%,90.11%,90.13%,85.26%on 3 d,7 d,15 d,30 d after dusting with 4%PG and 4%DP,respectively,in the fields. Statistics showed that the mortality rates of snails were higher on 3 d,7 d after dusting with PG than DP(c23 d=731.57,c27 d=25.90,P<0.01),but there were no significant differences between PG and DP on 15d,30d af?ter dusting(c215 d=0.53,c230 d=0.01,P>0.05). Conclusions 4%PG has both the adsorption of powder and the penetrability of the granules. The molluscicidal effects of 4%PG and 4%DP are almost the same. However,the drift of the powder was still not effectively controlled. This problem need to be further studied.
3.Further study on possibility of diffusion of Oncomelania hupensis with water in river channels of the east route of South-to-North Water Diversion Project
Yixin HUANG ; Derong HANG ; Hongping TANG ; Daokuan SUN ; Canhua ZHOU ; Jinbin GAO ; Bo ZHENG ; Guiquan HU ; Qian LI ; Yongjun HUANG ; Guangsong SHE ; Zhiyuan REN
Chinese Journal of Schistosomiasis Control 2014;(6):608-612,617
Objective To study the drifting law of floats and potential risks of Oncomelania hupensis diffusion in the water diversion rivers of the east route of South?to?North Water Diversion Project. Methods The O. hupensis snails in the river chan?nels were monitored by the salvage method and snail luring method with rice straw curtains,and the diffusion possibility of snails along with water was assessed through the drift test of floats with GPS. Results In the flood seasons from 2006 to 2013, totally 8 338.0 kg of floats were salvaged,and 2 100 rice straw curtains were put into water in the Li Canal and Jinbao shipping channel,but no Oncomelania snails were found. The drift test of floats with GPS before water diversion showed that the flow ve?locity on water surface(northbound)was 0.45 m/s,the average drift velocity of the floats was 0.56-0.60 m/s,and the average drift distances each time were 999.70- 1 995.50 m in the Gaoshui River section,while there were no obvious drift in Jinbao shipping channel section. During the water diversion period,the flow velocity on water surface(northbound)was 0.45 m/s,the average drift velocity of the floats was 0.35-0.41m/s,and the average drift distances each time were 1 248.06-1 289.44 m in the Gaoshui River,while in Jinbao shipping channel section,the flow velocity on water surface was 0.28 m/s,the average drift velocity of the floats was 0.25- 0.27 m/s,and the average drift distances each time were 477.76- 496.38 m. The drift test showed that the floats gradually closed to the river bank as affected by water flow,wind direction and ship waves,when blocked by the reeds,water plants or other obstacles,and they would stopped and could not continue to drift without outside help. Con?clusions There are no Oncomelania snails found in the river channels of the east route of South?to?North Water Diversion Proj?ect. The drifting distance of the floating debris along with the water is restricted by the flow rate and shore environment.
4.Application of targeted temperature management in the treatment of cardiac arrest in adult patients
Yue HU ; Xintao WANG ; Derong CUI
Chinese Critical Care Medicine 2018;30(5):490-493
Cardiac arrest (CA) is a fatal condition with low resuscitation rate and high mortality rate. Most of the survivors have neurological sequelae affecting their quality of life. Targeted temperature management (TTM) has been suggested by a number of studies to increase the survival rate and improve neurological outcome of CA. It is highly recommended by the International Liaison Committee on Resuscitation (ILCOR) for unconscious patients after resuscitation. In this review, we discuss the pathological mechanism of brain injury in CA and applications of TTM in adults with CA, with the aim of providing valuable information for clinical application.
5.Retrospective analysis of OGTT results of 26 558 pregnant women
Song YI ; Derong PAN ; Xingwen HU
Journal of Public Health and Preventive Medicine 2021;32(6):92-94
Objective To investigate the prevalence of gestational diabetes mellitus (GDM) among pregnant women in Wuhan, and to explore the application value of oral glucose tolerance test (OGTT) results in the screening, diagnosis and treatment of GDM. Methods A retrospective analysis was carried out on the OGTT results of 26 558 pregnant women from Hubei Maternal and Child Health Hospital from January 2018 to December 2018. Results (1) A total of 1 754 cases were diagnosed with GDM, with a positive rate of 6.60%. Among them of 776 had fasting blood glucose ≥5.1mmol/L, 880 had 1-hour blood glucose ≥10.0mmol/L, and 798 had 2-hour blood glucose ≥8.5mmol/L. (2) The positive rates of fasting blood glucose, 1-hour blood glucose, and 2-hour blood glucose in the ≥35-year-old age group were all over two times higher than those in the <35-year-old age group (all P<0.01). (3) The ratio of people with single-point positive, two-point positive and three-point positive was 7:2:1. (4) FBG, 1-hour blood glucose and 2-hour blood glucose concentrations were all positively correlated with each other (all P<0.01). Among these, the positive correlation between 1-hour blood glucose and 2-hour blood glucose was the most significant (r=0.618, P<0.01). Conclusions The incidence rate of GDM among pregnant women in Wuhan reached 6.60%, and the prevalence in pregnant women over 35 years old was significantly higher. Blood glucose level during pregnancy should be monitored for early detection and intervention to prevent the development of GDM. The relationship between blood glucose concentrations at different time points in the OGTT test had reference value for clinical diagnosis and treatment.