1.Lymph node metastasis pattern in patients with T2 and middle thoracic esophageal squamous cell carcinoma
Kunshou ZHU ; Feng WANG ; Derong ZHANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2011;27(5):289-290
Objective To investigate the pattern of lymph node metastasis in patients with 17 and middle thoracic esophageal squamous cell carcinoma( ESCC). Methods Retrospective review the clinical data of 246 cases with T2 and middle thoracic esophageal squamous cell carcinoma who were treated by three-field lymphadenectomy. Analyze the relationship between clinical pathological factors and lymph node metastasis. Results Lymph node metastases were found in 129 of the 246 patients (52.4% ).The average number of resected lymph nodes was 25 per patient (rangel5 -59). The rates of lymph node metastasis were 28.9% in the neck, 28.5% in thoracic mediastinum and 22.0% in abdominal cavity for patients with T2 and middle thoracic ESCC. No significant difference in lymph node metastasis' rate was observed among the neck, thoracic mediastinum and abdominal cavity. Logistic-regression showed the length of tumor, tumor cell differentiation and angiolymphatic invasion were factors influencing lymph node metastasis. Conclusion Lymph node metastasis in T2 and middle thoracic ESCC has the characteristics of upward, downward and skip spreading. Patients with T2 and middle thoracic ESCC should be treated with radical surgery with three-field lymphadenectomy.
2.Clinical Observation of Combined Acupuncture and Scraping Therapy for Improving Phlegm-dampness Constitution of Simple Obesity
Yueling PENG ; Jiang MENG ; Derong FENG ; Yuanchun XIAO
Journal of Acupuncture and Tuina Science 2009;7(2):87-90
Objective:To observe the clinical efficacy of combined acupuncture and scraping therapy for simple obesity and its effects on phlegm-dampness constitution.Methods:Seventy subjects with phlegm-dampness constitution were divided into treatment group and control group with a randomized digital table.Control group was given health education and dietary instructions,and treatment group was given acupuncture and scraping therapy besides health education and dietary instructions.After four-week treatments,the scores of obesity and phlegm-dampness constitution were recorded to assess the clinical efficacy.Results:There was a striking difierence in the total effective rate in treating obesity between the two groups (P<0.01);combined acupuncture and scraping therapy can relieve the phlegm-dampness symptoms(P<0.01);but the phlegm-dampness symptoms were not improved in the control group(P>0.05).Conclusion:Combined acupuncture and scraping therapy is quite effective for simple obesity and in improving phlegm-dampness constitution of simple obesity people.
3.Role of local anaesthesia video-assisted thoracoscopic surgery in diagnosis and treatment of open thoracic trauma
Qingyong CAI ; Huaihua XING ; Gang XU ; Guiyou LIANG ; Derong HUANG ; Hui CHEN ; Feng WANG
Chinese Journal of Trauma 2014;30(3):260-263
Objective To investigate the feasibility and superiority of local anaesthesia video-assisted thoracoscopic surgery (LA-VATS) in diagnosis and treatment of open thoracic trauma (OTT).Methods Seventy-eight patients with OTT emergently admitted from February 2007 and June 2012 were randomized into LA-VATS group (n =37) and conventional treatment group (n =41) by the toss of a coin.In the LA-VATS group,further treatment was determined following LA-VATS.Volume of chest tube drainage,duration of chest tube placement,average length of hospital stay,and postoperative complications were measured and compared between groups.Results In the LA-VATS group,23 patients completed LA-VATS and 14 were transferred for simple VATS-assisted mini-thoracotomy under general anesthesia.In the conventional treatment group,24 cases completed debridement and chest drainage and 17 cases were transferred for thoracotomy under general anesthesia.Volume of chest tube drainage [(195.0 ± 150.8) ml/d∶ (480.0 ±212.3)ml/d] (t =-2.675,P <0.05),duration of chest tube placement [(2.6 ± 1.4) d∶ (3.8 ± 1.9) d] (t =-2.318,P < 0.05),average length of hospital stay [(6.4 ±2.3) d ∶ (10.9 ± 3.3) d] (t =-2.471,P < 0.05),and incidence rate of postoperative complications (10.8% ∶22.0%) (x2 =4.132,P <0.05) were all significantly different between LA-VATS and conventional treatment groups.Conclusion LA-VATS is safe and feasible for diagnostic exploration and simple treatment of OTT.
4.Efficacy of Xiangsha Yangwei Wan in Inhibiting Side Effects due to Chemotherapy in Upper Digestive Tract
Weikua ZHENG ; Lizhu LIN ; Shude CHEN ; Feng ZHAN ; Jiaqi RAO ; Derong XIE ; Mingzhi HAO
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(06):-
[Objective] To investigate the efficacy of Xiangsha Yangwei Wan (XYW) on the inhibition of chemotherapy-induced chemical gastritis and upper gastrointestinal symptoms. [Methods] A randomized controlled trial (RCT) was carried out in 87 cases of maligant tumor confirmed by histopathological and cytological examination. All the cases were treated with chemotherapy regimen of adriamycin ( ADM) , adcarbazine ( DTIC) , platinum-based agents, irinotecan (CPT-11) and fluorouraeil (5-FU). Meanwhile, 41 cases in group A were also treated with dexamethason and 5-HT3 receptor antagonist as an essential anti-emesis and with XYW to regulate gastrointestinal function; other 46 cases in group B were given dexamethason and 5-HT3 receptor antagonist only. Seven days after treatment, incidences of chemical gastritis and upper gastrointestinal symptoms were observed and compared between the two groups. [Results] Seven days after chemotherapy, upper gastrointestinal symptoms and signs were relieved in 95.1% (39/41) of the patients of group A and in 76.1 % (35/46) of group B; the occurring rate of chemical gastritis with symptoms was 2.4% (1/41) in group A and 19.6% (9/46) in group B, the differences being significant statistically between the two groups( P - 0.0122) . [ Conclusion ] XYW has an inhibitory effect on chemotherapy-induced chemical gastritis and upper gastrointestinal symptoms.
5.Analgesic effect of auto-moxibustion on lumbar vertebral osteoarthritis
Qiongyu XU ; Derong FENG ; Fen ZHU ; Jiaming DONG ; Minghua LIANG ; Yina OU
Modern Clinical Nursing 2013;(5):14-15,16
Objective To investigate the analgesic effect of auto-moxibostion on lumbar vertebral osteoarthritis? Methods Sixty patients with lumbar vertebral osteoarthritis were randomized equally into the control group and observation group by a random digits table: the former group received routine nursing care and the latter was intervened with auto-moxibustion together with routine nursing care? The curative effects were appraised by short-form of McGill pain questionnaire? Result The curative effect in the observation group was significantly better than that of the control group(P < 0?05)? Conclusions The auto-moxibustion is effective for the analgesia of lumbar vertebral osteoarthritis? The right management of medication and detained medicine is helpful for the increased effect of auto-moxibustion?