Objective Objective Research on the change of levels of interleukin 12 (IL-12),interleukin4 (IL-4) and immunoglobulin E(Ig E)in asthmatic children.Methods 20 asthmatic children in attack stage and 20 asthmatic children in remission stage were as sample cases.The serum levels of IL-12,IL-4 and Ig E were detect with ELISA.Results IL-12 level of children in attack stage was obviously lower than those in remission stage and healthy children (P＜0.05);IL-4 and Ig E level of children in attack stage was obviously higher than those in remission stage and healthy children (P＜0.05);IL-4 level of children in remission stage was obviously higher than healthy children (P＜0,05);The level of IL-12 was in negative correlation with that of IgE in asthmatic children,while the level of IL-4 was in positive correlation with that of IgE in asthmatic children.Conclusions Asthmatic children have lower level of IL-12 and higher levels of IL-4 and Ig E.

Objective To study the effects of treating irritable bowel syndrome (IBS) with modified TongXieYaoFang. Methods 83 IBS patients were randomly recruited into a treatment group (45 patients) and a control group (38 patients). In the control group, Trimebutine, 200mg, and Bifid triple viable capsule, 420mg, 3 times/day was given orally to the patients, while on the basis of that, the treatment group was administrated with modified TongXieYaoFang in addition. Both groups were treated for one course of 4 weeks. Results The total effective rate of the treatment group and the control group was 93.3% and 71.1% respectively, showing significant difference between the two groups (X2=7.2938, P<0.01 ). Conclusion TongXieYaoFang combined with western medicine is effective in treating IBS.

Objective To investigate certified specialized nurses' willingness in building an reappraisal system and to provide a basis for further completing the appraisal system and criteria for specialized nurses, defining their roles, and encouraging them to play their leading roles in clinical work.Methods Totally 250 certified specialized nurses from 8 Class Ⅲ hospitals in Beijing were selected by convenient sampling and investigated with the self-designed questionnaire. The subjects' willingness in building the reappraisal system and criteria were analyzed.Results In terms of the 240 specialized nurses' wiliness in building the reappraisal system, their scores in clinical competence, teaching ability and research capability were (13.14±3.86), (13.60±2.27) and (9.50±2.94), respectively. There was statistical difference in the willingness in building the evaluation criteria of clinical competence between specialized nurses with different length of service and titles (P<0.05); there was also statistical difference in the willingness in building the evaluation criteria of teaching ability between specialized nurses with different educational background (P<0.05).Conclusions The specialized nurses' willingness in building the reappraisal indicators. Nursing managers shall train specialized nurses based on their shortcomings, build stricter criteria for future training for specialized nurses, and encourage the nursing team to become expert nurses.