1.Observation of short-term curative effect of Suxiao Jiuxin Pill on coronary heart disease and angina pectoris
Shenghai CAO ; Xiaoxia YAN ; Jiayi ZHANG ; Guangmei ZHANG ; Yanyan ZHANG ; Denghai LA ; Fang SUN
Chinese Traditional Patent Medicine 1992;0(04):-
AIM: To observe the short-term curative effect of Suxiao Jiuxin Pill on coronary heart disease (CHD) and angina pectoris. METHODS: 187 patients were divided into two groups at random:the treatment group with 105 cases and the control group with 82 cases. The treatment group was given Suxiao Jiuxin Pill 6 pills tid and the control group was given Compound Danshen Dripping Pill 6 pills tid orally. The treating period was 2 weeks. Before and after treatment angina pectoris was observed and electrocardiogram was determined. RESULTS: Suxiao Jiuxin Pill could significantly alleviate syndrome of CHD in patients, lessen electrocardiogram and decrease dosage of nitroglycerin. The total effective rate on angina pectoris and the effective rate in improving electrocardiogram was higher in treatment group than that in control group (P
2.Epidemiological characteristics and changes of D-D and FIB levels in patients with high-altitude pulmonary thromboembolism
Yaoyu QI ; Denghai LA ; Yanting SUN
Journal of Public Health and Preventive Medicine 2021;32(5):145-148
Objective The epidemiological characteristics of high-altitude pulmonary thromboembolism (PTE) were investigated, and to enhance people's cognitive level of high-altitude PTE. Methods A tatal of 286 patients with PTE admitted to our hospital from May 2017 to October 2019 were selected and divided into study group (n = 143) living at high altitude of 2500 ~ 4500 m and control group (n=143) living at low altitude of 1500~2450m according to altitude.The clinical data, D-D, FIB levels, and laboratory routine examinations were compared between the two groups, and the risk factors were analyzed using univariate analysis and the independent risk factors were analyzed by multivariate logistic regression. Results The levels of D-D and FIB in the control group were significantly increased (P<0.05). Univariate analysis showed that high altitude polycythemia, hemoglobin, hypoxemia, pulmonary hypertension, D-D level, FIB level, lower extremity deep venous thrombosis, pulmonary heart disease, dyspnea and chest pain were all risk factors of PTE at high altitude. Multivariate logistic regression analysis showed that red blood cell count, HGB level, increased hemoglobin concentration, DVT and D-D level were independent risk factors of PTE at high altitude. There was no significant difference in the general data (gender, age, occupation) between the two groups (P > 0.05). Conclusion Those were independent risk factors affecting the incidence of PTE at high altitude,including multivariate logistic regression analysis indicated that red blood cell level, HGB level, DVT, D-D, and FIB. The higher the plasma D-D and FIB levels, the recurrence interval, especially the related diseases of patients at high altitude need regular monitoring.