1.Comparison between Traditional Indian Medicine and Traditional Chinese Medicine
International Journal of Traditional Chinese Medicine 2008;30(4):314-316
We made comparisons between traditional Indian medicine and traditional Chinese medicine from several treatrnent methods of the two medicines,etc.
2.Analysis to construction of literature exchange platform between TCM libraries of Across-Straits
International Journal of Traditional Chinese Medicine 2011;33(1):59-60
Objective To explore the feasibility of constructing literature exchange platform between TCM libraries of Across-Straits, focusing on current situation of TCM libraries. Methods Originally scattered,multivariant, and isomeric TCM literature resources were united to one whole through simple and effective mode for the purpose of increasing literature usage. Results The exchange platform between TCM libraries of Across-Straits was established. Conclusion This platform was suitable for scientific research, teaching,clinical practice and science popularization.
3.Correlation of expressions of TGF-β1, Smad7 and ki-67 mRNA and the clinicopathologic characteristics in gastric carcinoma
Chunhui LI ; Lihui PAN ; Deli ZHANG
The Journal of Practical Medicine 2014;(5):751-754
Objective To investigate relationship between the expressions of TGF-β1 mRNA, Smad7 mRNA and ki-67 mRNA and the clinicopathologic characteristics in gastric carcinoma. Methods 60 cases with gastric carcinoma tissue and 20 cases with normal gastric tissue, which were surgically removed and certified by pathology, were collected. The expressions of TGF-β1 mRNA, Smad7 mRNA and ki-67 mRNA were detected by RT-PCR in normal and carcinomatous gastric tissue. Results The expressions of TGF-β1 mRNA, Smad7 mRNA and ki-67 mRNA in normal gastric tissue were lower than those in carcinomatous gastric tissue (P < 0.05). The expressions of TGF-β1 mRNA, Smad7 mRNA and ki-67 mRNA in gastric carcinoma which were well differentiated and moderately differentiated were significantly lower than those in poorly differentiated gastric carcinoma (P<0.05). The expressions of TGF-β1 mRNA, Smad7 mRNA and ki-67 mRNA in gastric carcinoma without lymph node metastasis were lower than those in gastric carcinoma with lymph node metastasis. The expressions of TGF-β1 mRNA, Smad7 mRNA and ki-67 mRNA in Ⅰ+Ⅱ stage were lower those in Ⅲ+Ⅳ stage (P < 0.05). Linear correlation showed there were positive correlations among TGF-β1 mRNA, Smad7 mRNA and ki-67 mRNA in gastric carcinoma. Conclusions The canonical TGF-β1 Smad7 and Ki-67 mRNA play a role in the carcinogenesis, development, differentiation of gastric carcinoma.
4.Advances in the application of nucleus pulposus stem cells in nucleus pulposus tissue engineering
Xiaochuan LI ; Deli WANG ; Dike RUAN
Chinese Journal of Orthopaedics 2017;37(6):377-384
Intervertebral disc degeneration (IVDD) takes great affection on people health all over the world.With the extension of human life and aging,the number of sick people will grow rapidly.At present,both conservative and surgical treatment can only alleviate the symptoms,rather than the fundamental treatment for the process of degeneration.Therefore,the application of cell therapy in the treatment of degenerative disc regeneration is an innovative treatment.However,it's a great bottleneck for exogenous transplanted stem cells to survive in degenerated intervertebral disc with harsh environment containing strong force,acidic pH,hypoxia,hyperosmolarity and limited nutrition.In recent years,tissue endogenous repair has been demonstrated to be present in almost all human tissues,and endogenous stem cell play an important role in the process.Similarly,nucleus pulposus was also confirmed the existence of such a kind of tissue specific stem cells-nucleus pulposus derived stem cells (NPSCs)-a new promising candidate for the treatment of IVDD.NPSCs,as a new kind of stem cells,hold either the characteristic of stem cell and the special potential of themselves,such as the nice adaption of the environment in intervertebral disc and the superior potential of cartilage differentiation.Nonetheless,the isolations of NPSCs were different;cell phenotypes were lack of wildly acceptable standard and the biological characteristics were various among different NP sources.In addition,whether the application of NPSCs could be used in nucleus pulposus tissue engineering still calls for further research.Due to the unclear in degeneration mechanism of IVDD,the study on degeneration mechanism of NPSCs may play a great important role in clarifying this issue.
5.Construct management and monitoring platform of TCM information system based on open source software
Li KANG ; Haiyan LI ; Deli YANG ; Xianrong WEN ; Qiang LI
International Journal of Traditional Chinese Medicine 2010;32(6):520-522
Config and modify open source software such as Nagios、 MRTG and Awstats, make it more suitable and stable for our network environment. Construct server monitor、 service monitor、 network monitor and website statistics system by using open source software. Besides, we construct network resource management system via ASP and database technology.Finish the network and service monitoring and management system based on B/S architecture. This system can keep close watch on the status of servers and services running on servers, and ensure all of the servers and services normal running, and provide the basic information service for policy-making body and other research institute.
6.An inveatigation on adsorptive effect of attapulgite with Tanshinone Ⅰand Tanshinone Ⅱ_A in traditional Chinese medicine decoction
Xiaoqiang LI ; Ping LI ; Qin WEI ; Deli ZHANG
Chinese Journal of Biochemical Pharmaceutics 2010;31(2):114-117,121
Purpose To investigate the adsorptive effect of attapulgite on Tanshinone Ⅰ and TanshinoneⅡ_A in decoction of Radix et Rhizoma Salviae Mihiorrhizae and Composite Dansen Pill.Methods Using the amount of solid component and the content of Tanshinone Ⅰ and Tanshinone Ⅱ_A as index,the adsorptive effect of common attapulgite and acidified attapulgite on decoction of Radix et Rhizoma Salviae Miltiorrhizae and Composite Dansen Pill was investigated respectively and the content of Tanshinone Ⅰ and Tanshinone Ⅱ_A was determined by HPLC.Results Common attapulgite could not markedly decreased the amount of solid component and had a litfle effect on the content of Tanshinone Ⅰ and TanshinoneⅡ_A in decoction of Radix et Rhizoma Salviae Miltiorrhizae and Composite Dansen Pill.The acidified attapulgite could obviously decrease the amount of solid component and had a little effect on the content of Tanshinone Ⅰ and TanshinoneⅡ_A in decoction of Radix et Rhizoma Salviae Miltiorrhizae and Composite Dansen Pill.Conclusion Acidified attapulgite could be used as adsorptive clarifier in decoction of Radix et Rhizoma Salviae Miltiorrhizae and Composite Dansen Pill.
7.The clinical treatment of tracheoesophageal fistula by coated stent in trachea
Fanzheng MENG ; Lina WANG ; Li ZHANG ; Deli LI
Chinese Journal of Applied Clinical Pediatrics 2015;30(16):1206-1208
Tracheoesophageal fistula is divided into congenital and acquired tracheoesophageal fistula in the children.The main treatment is surgery,but recurrent tracheoesophageal fistula and acquired tracheoesophageal fistula caused by corrosive substance are not suitable for surgery in the short term.Endoscopic interventional therapy has become a new way of treatment,closure of tracheoesophageal fistula using a coated stent in the trachea can win time for surgical treatment and the fistula may reach the natural healing.It is an effective way of treatment.
8.Protective effects of choline on myocardial ischemic rat heart and its potential mechanisms
Hairong LUAN ; Jian SUN ; Deli WANG ; Li LI ; Hong WU
Chongqing Medicine 2016;45(17):2305-2307
Objective To study the protective effects of choline on myocardial ischemia rat heart and its potential mecha -nisms .Methods Ischemia hypoxia environment was simulated with low value of pH (pH 6 .8) and lack of oxygen .Calcium currents were recorded by whole cell patch under the voltage clamp configuration .The alternations in[Ca2 + ]induced by KCl was detected by laser scanning confocal microscope in ventricular myocytes ,then disccuss the effects of choline on calcium and calcium store in cells . Results The normalized peak currents of ICa-L in ventricular myocytes were larger in pH 6 .8 group than those in pH 7 .4 group , which can be attenuated by choline .The(Ca2 + )i induced by KCl in ventricular myocytes were significantly increased in pH 6 .8 Ty-rode solution and its increasing can be suppressed by choline .4-DAMP can inhibit the suppressing effect of choline .Conclusion The possible mechanism of M 3 receptor involved in the protection of ischemic myocardium by inhibiting myocardial cells in ICa-L ,in-hibiting intracellular calcium overload .
9.On the construction of the standardized digital scientific research platform of traditional Chinese medicine
Hongjie GAO ; Jinghua LI ; Li KANG ; Deli YANG
International Journal of Traditional Chinese Medicine 2013;35(9):815-817
To carry out research on the construction of standardized digital research platform of traditional Chinese medicine.Beginning from the consolidation of data usage resources,the strengthening of environmental construction,the improvement of quality on database creation and the perfection of training mechanism,the construction of standardized digital research platform of traditional Chinese medicine can be improved with the times,adapting to the times and meeting the demands of society.To meet the demands,the construction of digital scientific research foundation platform was perfected by improving quality and emphasizing on application.The service capabilities of standardized Chinese medical information can be promoted by establishing a new information scientific research model.
10.CT-guided radiofrequency ablation for the treatment of early stage non-small-cell lung cancer:clinical analysis of 60 cases
Jingqi HAN ; Chuanyu ZHANG ; Yong LI ; Changgong CHI ; Deli PAN
Journal of Interventional Radiology 2015;(5):414-417
Objective To evaluate the safety, efficacy and local control effect of CT- guided radiofrequency ablation (RFA) in treating non-small-cell lung cancer (NSCLC) that is inoperable or the surgical treatment is refused by the patient. Methods Between March 2007 and March 2010 at authors’ hospital, a total of 68 procedures of CT-guided RFA were carried out in 60 patients with early stage NSCLC. The patients included 37 males and 23 females with a mean age of 68.5 years. Pathologically, the lesions included squamous cell carcinoma (n=23, 38.3%), adenocarcinoma (n=31, 51.7%), large cell carcinoma (n=2, 3.3%) and adeno-squamous carcinoma (n=4, 6.7%). The mean diameter of the lesions was 3.8 cm (1.8-6.8 cm). The overall survival rate, cancer-specific survival rate and local progression-free survival rate were evaluated. Results RFA procedure was well tolerated by all patients with an average ablation time of 35 min (18-63 min). The main intraprocedural complication was pneumothorax (n=17, 28.3%). No death occurred during perioperative period. The median local progression-free survival time was 28 months, the median survival time was 32 months, and the one-, 2- and 3-year local progression-free survival rate were 94.6%, 83.1%and 73.6%, respectively. Conclusion For patients with inoperable NSCLC and patients with NSCLC who refuse to receive surgery, CT-guided RFA is a safe and effective treatment. This therapy can significantly improve the local progression-free survival rate.