Objective To explore the diagnosis and treatment of hyperthyroidism in the pregnant women to improve maternal and infant healthy. Methods 47 cases of pregnant women with hyperthyroidism were divided into the treatment group receiving anti-thyroid drug PTU and the non-treatment group, and 30 cases of normal pregnant women served as control. The levels of serum T 3, T 4, TSH, FT 3 and FT 4 were measured before delivery, and the neonatal thyroid functions were evaluated by detecting the levels of T 3,T 4 and TSH of umbilical blood, as well as peripheral blood at 3th, 5th and 7th days after birth. Results The levels of T 3,T 4, TSH,FT 3 and FT 4 in the non-treatment group were significantly higher than those in the treatment group and control group(P

Objective To investigate the cause of continuous cropping obstacle of Rehmannia glutinosa and screen beneficial bacteria.Methods In vitro cultured plantlets and potted plants were inoculated with different isolated soil bacteria. The plants were harvested and weighted in 30 and 60 d,respectively.Results In the in vitro culture experiment,11 out of 48 strains displayed promoting action on the growth of plantlets,and 11 other strains showed inhibitory or lethal action.In the potted test,16 strains showed promoting action and 13 strains showed suppressing or lethal action.Conclusion Soil bacteria influence the growth of R.glutinosa significantly.The flora of rhizosphere bacteria may be disturbed by the cultivation of R.glutinosa and inoculation of beneficial bacteria might be effective on the resolution of continuous cropping obstacle of R.glutinosa.

Objective: To investigate the clinical efficacy and safety of percutaneous kyphoplasty at different surgical timings in the treatment of osteoporotic vertebral compression fracture (OVCF) based on the theory of “dynamic-static integration”. Methods: Patients with OVCF who underwent percutaneous kyphoplasty in our hospital were selected and divided into Groups A, B, and C for those undergoing surgery within 7, 7–21, and >21 days of fracture occurrence. The variations in the amount of bone cement injected, pre- and post-operative pain levels, functional activity, deformity correction of the injured vertebrae, bone cement leakage, and vertebral body height loss were compared among the three groups. Results: Regarding pain relief and functional activity, the postoperative Visual Analog Scale and Oswestry Disability Index scores of the three groups significantly improved. Furthermore, the deformities of the injured vertebrae in the three groups were significantly corrected, with Groups A and B exhibiting superior correction compared to Group C. Moreover, the bone cement leakage rates in groups A and C were higher than that in Group B. At the 3-month follow-up, the loss of vertebral height in Group C was significantly higher than those in groups A and B. Conclusion Kyphoplasty is effective for OVCF treatment. Early surgery can effectively restore the vertebral height of the injured vertebra, reduce kyphosis, and reduce height loss of the injured vertebra after surgery; nevertheless, treatment within 1–3 weeks of the fracture can reduce the occurrence of bone cement leakage, making the surgery safer. Therefore, surgical treatment within 1–3 weeks of fracture is safer and can achieve satisfactory therapeutic effects. From the perspective of traditional Chinese medicine, PKP surgery can transform the fracture end from a micromotion state to a fixed state, which fully embodies the theory of “dynamic-static integration”.

Colon cancer is a common malignant tumor in the world, however, its pathogenesis still needs further research. FEZF1- AS1 is highly expressed in colon cancer and other malignant tumors, and is associated with clinicopathological features and prognosis of colon cancer patients. In addition, FEZF1- AS1 promotes the proliferation, invasion and migration of colon cancer cells, regulates the cell cycle and inhibits apoptosis through various mechanisms, suggesting that FEZF1- AS1 may be a new important molecular biomarker and a potential therapeutic target for colon cancer. This article reviews the advances in the study of function and mechanism of FEZF1- AS1 in colon cancer.