Objective To explore the diagnosis and treatment of hyperthyroidism in the pregnant women to improve maternal and infant healthy. Methods 47 cases of pregnant women with hyperthyroidism were divided into the treatment group receiving anti-thyroid drug PTU and the non-treatment group, and 30 cases of normal pregnant women served as control. The levels of serum T 3, T 4, TSH, FT 3 and FT 4 were measured before delivery, and the neonatal thyroid functions were evaluated by detecting the levels of T 3,T 4 and TSH of umbilical blood, as well as peripheral blood at 3th, 5th and 7th days after birth. Results The levels of T 3,T 4, TSH,FT 3 and FT 4 in the non-treatment group were significantly higher than those in the treatment group and control group(P

Colon cancer is a common malignant tumor in the world, however, its pathogenesis still needs further research. FEZF1- AS1 is highly expressed in colon cancer and other malignant tumors, and is associated with clinicopathological features and prognosis of colon cancer patients. In addition, FEZF1- AS1 promotes the proliferation, invasion and migration of colon cancer cells, regulates the cell cycle and inhibits apoptosis through various mechanisms, suggesting that FEZF1- AS1 may be a new important molecular biomarker and a potential therapeutic target for colon cancer. This article reviews the advances in the study of function and mechanism of FEZF1- AS1 in colon cancer.