4.Clinical observation of the protective effects of Shenqi Fuzheng Injection on radiation therapy of nasopharyngeal carcinoma
Chinese Traditional Patent Medicine 1992;0(03):-
AIM: To study the protective effects of Shenqi Fuzheng Injection on radiation therapy of nasopharyngeral carcinoma. METHODS: 58 cases with nasopharyngeal carcioma were selected and divided into 2 groups randomly: 30 cases of treatment group (radiation therapy plus Shenqi Fuzheng Injection) and 28 cases of control group (radiation therapy only). Body weight, Karnofsky score, radioactive stomatitis and change of WBC were compared between the two groups. RESULTS: The rate of increasing and stable performance status(Karnofsky score) of treatment group and control group were 90.0% and 60.7%(P
7.Role of autophagy and apoptosis in tumor.
Jin-long TANG ; Hong-he ZHANG ; Mao-de LAI
Chinese Journal of Pathology 2012;41(8):573-576
Animals
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Antineoplastic Agents
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therapeutic use
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Apoptosis
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Apoptosis Regulatory Proteins
;
metabolism
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Autophagy
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physiology
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Beclin-1
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Humans
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Membrane Proteins
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metabolism
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Neoplasms
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drug therapy
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metabolism
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pathology
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Signal Transduction
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TOR Serine-Threonine Kinases
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metabolism
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Tumor Suppressor Protein p53
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metabolism
9.NOVEL ADVANCES ON PESTICIDES DEGRADATION BY MICROORGANISMS
Xiao-Hong YANG ; Jun LI ; Cheng GE ; De-Long SHEN ;
Microbiology 1992;0(06):-
Pesticides, especially chemistry pesticides with high toxicity, high residue, and difficult degradation are a kind of important environment pollutants and pesticide degradation by microorganisms is one of the powerful means to treat pesticide pollution. Many researchers conducted lots of studies on it. Types of pesticide degraders, construction of genetically engineered microorganisms, degrading mechanisms, degradation characteristics, influencing factors, applying effect and so on were summarized in this article. The research trend of degradation of pesticides by microorganisms and problems to be solved were also put forward.
10.Influlance of different drying methods on quality of Schisandrae Chinensis Fructus.
Kai-Long AN ; De-Kun LI ; Da-Zheng ZHOU ; Zheng-Liang YE ; Qiao-Sheng GUO
China Journal of Chinese Materia Medica 2014;39(15):2900-2906
OBJECTIVETo study the influence of different drying methods on the quality of Schisandrae Chinensis Fructus and thus provide useful reference for its proper drying methods.
METHODSchisandrae Chinensis Fructus was processed by eight drying methods including vacuum freeze drying, natural drying in the shade, drying in the sun, oven drying and vacuum drying under different temperature. The contents of the functional ingredients includes chisandrin, gomisin D, gomisin J, schisandrol B, angeloylgomisin H, angeloylgomisin Q, gomisin G, schisantherin A, deoxyschisandrin, schisandrin B, schisandrin C, 5-HMF, total aids and total sugars. The main components change after drying were analyzed by HPLC, ultraviolet spectrophotometry and potentiometric titration. Principal component analysis (PCA) was carried out by SPSS software to evaluate the quality of different processed products from Schisandrae Chinensis Fructus.
RESULTAll these results are in accordance with the requirements of Chinese Pharmacopoeia published in 2010, the contents of schisandrin and total eleven lignans were the highest using vacuum drying, and 5-HMF were the lower, oven drying made little difference but with lower schisandrin and higher 5-HMF as the heat increased.
CONCLUSIONDifferent drying methods have significant influence on the quality of Schisandrae Chinensis Fructus. Oven drying under 5°C should be adopted to substitute drying in the sun according to the China Pharmacopoeia published in 2010 for Schisandrae Chinensis Fructus by comprehensive analysis of the cost, content and practicality.
Desiccation ; methods ; Drugs, Chinese Herbal ; chemistry ; Quality Control ; Schisandra ; chemistry ; Temperature