1.Continuous and cyclic low dose oral contraceptive pills after laparoscopic oophorocystectomy and recurrence of ovarian endometriosis
Icamina Mary Karen Veronica R. ; De Guia-Fuerte Blanca
Philippine Journal of Reproductive Endocrinology and Infertility 2010;7():7-13
Conservative surgery is the treatment of choice for pelvic endometriosis. However, one of the most frustrating aspects of treating pelvic endometriosis is disease recurrence. As endometriotic tissue is hormonally sensitive, postoperative cyclic or continuous low dose monophasic oral contraceptive pills may be effective in preventing or delaying recurrence. Our results showed no statistically significant difference between the recurrence rates of patients who were cyclic or continuous OCP users. Symptom and bigger anatomic recurrences were observed among cyclic OCP users. Post operative OCP use and duration of treatment did not significantly influence time to disease recurrence. The risk of recurrence of endometriotic cyst seemed higher among cyclic OCP users. Further, statistically powered randomized controlled trials with bigger sample size, long term use and longer follow up period are necessary to better provide recommendations regarding the OCP administration regimen.
Human
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ENDOMETRIOSIS
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RECURRENCE
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PELVIC PAIN
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LAPAROSCOPY
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CONTRACEPTIVES, ORAL
2.The effect of laparoscopic ovarian cystectomy on the ovarian reserve in women admitted for endometriotic cysts at the tertiary hospital
Ranola Leedah ; Banal-Silao Maria Jesua ; De Guia-Fuerte Blanca
Philippine Journal of Reproductive Endocrinology and Infertility 2011;8(2):55-61
Objective: To compare pre-operative and post-operative ovarian reserve by measuring the follicle stimulating hormone (FSH) serum level on day 3 of the menstrual cycle following a laparoscopic ovarian cystectomy for endometriotic cyst/s.
Design: Prospective descriptive study
Setting: Tertiary referral center.
Study Population: Patients who are 18 to 34 years old with unilateral/bilateral endometriotic cyst/s were recruited in the study. All patients underwent laparoscopic ovarian cystectomy at the charity service of Reproductive Endocrinology and Infertility Section in a tertiary hospital.
Outcome Measures: Serum day 3 FSH was determined pre-operatively and 1 month post-operatively and analyzed for statistical significance.
Results: Majority of our patients aged 31-34 years old, were nulligravid and with history of infertility. The mean post-operative FSH level decreased slightly compared to the pre-operative FSH level. The size and number of endometriotic cyst did not affect significantly the ovarian reserve as well as the ovarian residual volume. Likewise, the menstrual pattern did not significantly change post-operatively.
Conclusion: The mean overall postoperative FSH level improved very slightly but is not significant. Somehow, laparoscopic ovarian cystectomy may be beneficial in improving the ovarian reserve. However, further studies and samples are needed.
Human
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Female
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Adult
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Young Adult
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FOLLICLE STIMULATING HORMONE
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LAPAROSCOPY
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ENDOMETRIAL NEOPLASMS
3.Cervical cancer screening, HPV vaccine: Knowledge and attitudes of female adolescents seeking consult at Philippine Children's Medical Center.
Marie Anne Nghua-Ramos ; Blanca De Guia- Fuerte ; Ma. Socorro Bernardino
The Philippine Children’s Medical Center Journal 2017;13(1):64-79
OBJECTIVE: This study aims to assess the knowledge and attitudes of female adolescents aged 14-19 years old seeking consult at Philippine Children's Medical Center regarding cervical cancer screening and HPV vaccine.
DESIGN: Cross-sectional survey of mid to late adolescents.
METHODOLOGY: The survey questionnaire consists of 18 items in the domain of knowledge, attitudes, practice behaviors, barriers and demographic information. Survey forms in a sealed envelope were given to adolescents 14 to 19 years old after obtaining their assent and parents/guardians' consent.
RESULTS: There were a total of 107 respondents; majority belonged to the mid adolescents (14-16 years old), high school level and non sexually active 57%, 64% and 62% respectively. Most of the respondents (60%) were in a relationship or had a boyfriend, 61% engaged in a monogamous sexual relationship with their partners, 10% had 2 partners and 15% had more than 3 partners. There were significantly more late adolescents who are sexually active compared to mid adolescents (67.4% and 14.8%). Awareness of cervical cancer screening is only 23% of the surveyed adolescents (mean age 16.36). Majority of the sexually active respondents knew that HPV infection is through vaginal intercourse, and that pap smear is necessary even if no history of cancer in the family. More respondents with high education knew that avoidance of sexual intercourse, using condom and vaccination are all effective methods of HPV infection prevention. 53% of the respondents heard about HPV vaccine. Sources of information were mostly from the mass media. Majority were willing to receive the vaccine especially if given for free.
CONCLUSION: Knowledge on HPV and Cervical cancer prevention especially through pap smear is poor. Health education and improvement of personal practices should be emphasized as necessary factors for preventing HPV infection acquisition.
Human ; Adolescent ; Uterine Cervical Neoplasms- Diagnosis ; Papanicolaou Test ; Papillomaviridae