OBJECTIVE: To discuss the positive effect of the revolutionary step in drug circulation(Trusteeship of Hospital Drugstore) on the reduction of drug costs and patients' medical expenses as well as on hospital management and development.METHODS: Based on the practice of "Trusteeship of Hospital Drugstore" in our hospital,this article analyzed and expounded the nine "possible" biased view points put forward in research paper entitled "Thoughts on 'Trusteeship of Hospital Drugstore'" published in the magazine "China Pharmacy"(Issue 13 of Vol.18,2007 May).RESULTS & CONCLUSIONS: The innovative practice of "Trusteeship of Hospital Drugstore" carried out currently in Nanjing is an attempt beneficial for drug circulation,which plays a positive and effective role in controlling the drug price over a reasonable range and alleviating patients' burden on medical expenses.