2.Role of radiosynovectomy in the treatment of rheumatoid arthritis and hemophilic arthropathies
Biomedical Imaging and Intervention Journal 2007;3(4):1-5
Radiosynovectomy is a novel method of treatment for several acute and chronic inflammatory joint disorders. A
small amount of a beta-emitting radionuclide is injected into the affected joint delivering a radiation dose of 70 to 100
Gy to the synovia. The proliferative tissue is destroyed, secretion of fluid and accumulation of inflammation causing
cellular compounds stops and the joint surfaces become fibrosed, providing long term symptom relief. The radionuclides
are injected in colloidal form so that they remain in the synovium and are not transported by lymphatic vessels causing
radiation exposure to other organs. Complete reduction of knee joint swelling has been seen in above 40% and pain
relief in 88% of patients. Wrist, elbow, shoulder, ankle and hip joints showed significant improvement in 50-60% and
restoration of normal function and long term pain relief has been achieved in about 70% of small finger joints. In
hemophilic arthropathies complete cessation of bleeding in about 60% and improved mobility in 75% of patients has
been reported.
3.Clinical and hematological study of canine Ehrlichiosis with otherhemoprotozoan parasites in Kolkata, West Bengal, India
Asian Pacific Journal of Tropical Biomedicine 2013;(11):913-915
Objective: To observe other hemoprotozoan diseases with canine ehrlichiosis and to evaluate the clinical and hematological aspects of dogs naturally infected with ehrlichiosis with other hemoprotozoan diseases.Methods:Blood was collected for hematological value and Giemsa stained blood smear was made for diagnosis of Ehrlichia sp. and other hemoprotozoan parasites from naturally infected dogs. Case history was taken from the owner and clinical signs and symptoms were noted.Results:A total of 47 cases of ehrlichiosis in dogs were reported with babesiosis (8.51%) and hepatozoonosis (6.38%) hemoprotozoan diseases. Ehrlichia canis, Ehrlichia ewingii, Brucella canis,Babesia gibsoni and Hepatozoon canis were observed under oil immersion lense of microscope in Giemsa stained peripheral blood smears. Marked anaemia and neutrophilic leukocytosis were observed.Conclusions:The results of this study stated that clinical and haematological changes occurred in canine ehrlichiosis with babesiosis and hepatozoonosis due to parasitemia. In mixed infection, the disease more severe, and also it depended on immunity of animals. Babesia gibsoni andHepatozoon canis with Ehrlichia sp. were first reported from West Bengal state of India by this study.
4.Verteporfin therapy for subfoveal choroidal neovascularisation associated with choroidal osteoma
Nazimul HUSSAIN ; Taraprasad DAS
International Eye Science 2005;5(5):838-840
· AIM: To report a case of verteporfin therapy for subfoveal choroidal neovascularisation associated with choroidal osteoma.· METHODS: A 32-year-old patient was diagnosed as subfoveal choroidal neovascularisation (CNV) associated with choroidal osteoma in the right eye, with present visual acuity (VA) of 20/80; N24. He underwent 2 sessions of photodynamic therapy (PDT) in the right eye for 12mo.· RESULTS: At the end of 12mo, the patient's VA was 20/200 with complete regression of the CNV.· CONCLUSION: PDT could be a treatment option in subfoveal CNV associated with choroidal osteoma.
5.Common laboratory tests for rheumatologicaldisorders: how do they help the diagnosis?
Malaysian Family Physician 2009;4(2 & 3):48-50
No screening test is ideal for detecting rheumatic diseases; diagnosis depends on appropriate history and thorough physical examination. Sometimes, laboratory investigations may be useful in confirming or ruling out rheumatic disease after a clinical diagnosis is considered. Once a rheumatic disease has been diagnosed, certain laboratory tests can
help in assessing prognosis or determining the extent of the disease. Laboratory tests may also help the physician
monitor certain rheumatic diseases, guide treatment or assess potential drug toxicity.
6.An Unusual Presentation of Adult Onset Still’s Disease
Anirban Ghosal ; Radha Binod Pal ; Somak Kumar Das ; Tanima Das
The Medical Journal of Malaysia 2012;67(5):532-533
Adult onset still’s disease usually presents with high grade intermittent fever, polyarthritis, salmon pink evanescent rash and hepatosplenomegaly. Pulmonary involvement in the form of pneumonitis, as a presenting feature is very rare.
We report a case of a young lady who presented with fever,
cough and respiratory distress. Chest X-ray revealed patchy
infiltration in left upper lung zone. She was subsequently
diagnosed as Adult onset Still’s disease. There was no
improvement in clinical condition despite five days of
antibiotics. On trans-bronchial lung biopsy (TBLB) proved
she had interstitial pneumonitis and responded dramatically
to steroid treatment.
7.Dihydroxy-isosteviol methyl ester of Pulsatilla nigricans extract reduces arsenic-induced DNA damage in testis cells of male mice: its toxicity, drug-DNA interaction and signaling cascades.
Samadder, Asmita ; Das, Jayeeta ; Das, Sreemanti ; Das, Durba ; De, Arnab ; Bhadra, Kakali ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2012;10(12):1433-42
To evaluate the ameliorative efficacy of dihydroxy-isosteviol methyl ester (DIME) of Pulsatilla nigricans extract in arsenic-induced DNA damage in testis cells of mice.
8.Van der Knaap syndrome, a case from West Bengal, India
Subhra Aditya ; R Das Gupta ; D Das ; MK Roy ; T Dhibar, T Das
Neurology Asia 2010;15(2):193-195
Leucodystrophies are a group of white matter diseases caused by an abnormality in the formation or
maintenance of one or more components of the myelin sheath. The devastating course of the disease
coupled with the lack of any defi nitive treatment render them potentially fatal and incurable. Van der
Knaap Syndrome, also known as megaloencephalic leucoencephalopathy with subcortical cyst, is a
relatively new and rare entity. Although reported sporadically from Europe, Asia and the Agarwal
community in India, there is practically no case report from the eastern part of India. We present a
case of van der Knaap syndrome in an adult female with some atypical features.
9.Rapid green synthesis of silver nanoparticles from silver nitrate by a homeopathic mother tincture Phytolacca Decandra.
Bhattacharyya, Soumya Sundar ; Das, Jayeeta ; Das, Sreemanti ; Samadder, Asmita ; Das, Durba ; De, Arnab ; Paul, Saili ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2012;10(5):546-54
To examine if a homeopathic mother tincture (Phytolacca Decandra) is capable of precipitating silver nanoparticles from silver nitrate (AgNO(3)) and to characterize the biosynthesized nanoparticles for evaluating their biological activities.
10.Burnt wife syndrome.
Annals of the Academy of Medicine, Singapore 1984;13(1):37-42
While the system of offering dowry to the groom by the parents of the bride at the time of the marriage is an age old one amongst the Hindus of India; during the recent past this evil custom has resulted in a large number of newly wed young housewives being either killed or tortured to end their own lives by their husbands and in-laws, for the unfulfilled demands or desire for dowry from the parents or guardians of the bride. Indeed in India today, torture of the young housewives by their husbands and in-laws for failure to bring insufficient dowry has become the order of the day all over the country. Some of them are burnt to death and others choose to die by fire; while still others are put to death by some means other than fire and disposed of by burning in order to hide the heinous offence. Hardly a day passes in the life of a forensic pathologist working in one of the states of Northern India, when he is not called upon to do an autopsy on the dead body of a burnt housewife who almost invariably is a married Hindu woman in the prime of her youth, between 15-30 years of age.
Adolescent
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Adult
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Autopsy
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Burns
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pathology
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Female
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Forensic Medicine
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methods
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Homicide
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Humans
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India
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Spouse Abuse
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legislation & jurisprudence