2.The experimental study of Senxing granule in deferring aging
Shichang MEI ; Daoshan JIN ; Mianchuan WANG ; Xu CUI
Chinese Journal of Geriatrics 2003;0(07):-
Objective To investigate whether Senxing granule is effective on deferring aging and its mechanism. Methods The assay methods for life span of fruit fly and rat antioxidation were used for the study. Level of lipoperoxide, activity of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) in whole blood and liver tissue was measured. Low dose of Senxing granules in the culture medium was decided as 0.007 % and middle dose as 0.022 %. Results Low dose of Senxing granule significantly increased the mean life span of female fly by 3.7%( P
3.Effect of Xiaokehuayu Pills on blood glucose and superoxide dismutase activity of diabetic rats
Fawei WANG ; Aizhen HAO ; Liping CHEN ; Daoshan JIN ; Dongmei DUAN
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(08):-
Objective:To explore the influence of Xiaokehuayu Pills on blood glucose,superoxide dismutase(SOD) activity and malonaldehyde(MDA) of diabetic complicating hyperlipemia rats.Methods:Diabetes rat model was established by injection of alloxan with high fat diet.After the model formed,60 rats were been divided into 6 groups:normal control group,model group,high/middle/low dose groups of Xiaokehuayu Pills and Yuquan Pills group.The blood glucose and SOD activity and MDA content was measured before and after 6 weeks treatment.Results:The blood glucose in model group was signif icantly higher than that in normal control group(P