1.Chinical analysis of 32 cases with hepatic cirrhosis and diabetes mellitus
Chengshun ZHANG ; Daonian WANG
Chinese Journal of Primary Medicine and Pharmacy 2013;20(5):680-682
Objective To explore the pathogenicity and clinic character and treatment of patients with hepatic cirrhosis and diabetes mellitus.Methods Retrospectively analyzed clinic date of 32 cases with hepatic cirrhosis and diabetes mellitus.Results Among the 136 patients with cirrhosis,there were 32 patients having hepatogenous diabetes (which accounts for 23.5%).In the 32 patients with hepatogenous diabetes we found the patients with no family history of diabetes and before patients foured out that they were diabetic.The clinical manifestation of the diabetes was not typical.The main manifestation was that the glucose was low or moderately elevated when they were in empty stomach.The effective treatments for controlling diet,improving liver function and taking hypoglycemic medicine orally or injecting insulin.Conclusion Patients with cirrhosis tend to have disorders in their metabolism of carbohydrates,which might be related to the body resistance of insulin,glucose levels and the degree of the damage of their liver function.The treatment should emphasize on protecting the liver while controlling glucose level.Most cases have good recovery.
2.Multi-groups controled study on the association of Helicobacter pylori infection with gastric cancer and stomach diseases
Yongwen JIANG ; Runtian WANG ; Tao WANG ; Jieping ZHANG ; Daonian LEI
Journal of Peking University(Health Sciences) 2001;33(2):160-163
Objective: This multi-group case control study was performed to determine whether Helicobacter pylori infection was associated with gastric cancer and stomach diseases. Methods: Gastric cancer and stomach disease patients that were diagnosed pathologically between 1994 and 1996 years were divided into several case groups and control group, all histological specimens collected in gastric cancer high risk region of Shandong Province were used to measure exposure history. Results: After variables concerning age, sex and education were adjusted, odds ratios of chronic superficial gastritis in antrum, peptic ulcer disease and active degree of inflammation associated with H. pylori infection remained significant (OR was 2.072, 2.980, 2.086 respectively). Correlation analyses showed negative relationship between degree of stomach diseases and H. pylori infection(r=-0.217). Conclusion: The results support the hypothesis of a relationship between H. pylori infection and the development of chronic superficial gastritis in antrum, peptic ulcer disease and active degree of inflammation.