1.Hepatic eosinophilic granuloma misdiagnosed as liver metastases
Xuemin LI ; Daojun GONG ; Junqiang CHEN ; Bo ZHUANG ; Zhangdong ZHENG
Chinese Journal of Digestive Surgery 2014;13(3):227-229
Hepatic eosinophilic granuloma (HEG) is a rare benign liver disease,which belongs to histocytosis.Preoperative diagnosis of HEG was difficult because its clinical manifestation was not characteristic.In this article,the clinical data of 1 patient with HEG who was treated at the Jinhua Municipal Central Hospital of Zhejiang Province in September 2012 were retrospectively analyzed,and the diagnosis,differential diagnosis and treatment for HEG were investigated.
2.Clinical features, radiological characteristics, and pathological changes in 42 patients with cerebral sparganosis
Huiqun XIE ; Yong LONG ; Yun XU ; Zhihong GONG ; Hui WAN ; Daojun HONG
Chinese Journal of Neurology 2015;48(2):108-113
Objective To investigate the clinical features,the radiological characteristics,and the pathological changes of cerebral sparganosis.Methods We retrospectively collectted and summarized the clinical data of 42 patients with cerebral sparganosis from the Iinstitute of Anti-parasitic Diseases of Jiangxi Province and the First Affiliated Hospital of Nanchang University during January 2000 to January 2014.The follow-up period of the 42 patients ranged from 4 to 96 months.Results Forty-two cases (30 males and 12 females) with cerebral sparganosis were enrolled in the study.Among the 42 patients,34 cases suffered from seizures,16 cases experienced headaches,and 14 cases had limb weakness.The brain CT scan showed the small and punctuate calcifications scattering around the lesions in 18 cases.The features of enhanced MRI included aggregating ring-like enhancement in 38 cases,tunnel lesions in 14 cases,and lesion migration in 13 cases.Twenty-four of the 42 patients were performed surgery.The brain tissues revealed multiple inflammatory tunnels,in which live or degenerated larvae were identified in 20 cases,but only eosinophilia tunnels were observed in the other 4 cases.The serum and cerebro-spiral fluid specimens from 18 patients without surgery were positive to spirometra mansoni antigen.Their cerebral lesions disappeared and got a favorable prognosis after administration of praziquantel in long term follow-ups.Conclusions There is a high incidence of cerebral sparganosis in Poyang lake basin.The clinical features of cerebral sparganosis mainly include seizure,headache and hemiparesis.The enhanced lesions show knot or tunnel signs on multi-planar MRI which are associated with the multiple inflammatory tunnels of larvae migration.A longterm administration of high dose opraziquantel can also get a good treatment prognosis without the classical surgical therapy for cerebral sparganosis.
3.Effect of probucol on plasma adiponectin levels of patients with type 2 diabetes mellitus
Qiangxiang LI ; Huiju ZHONG ; Feiyue ZHU ; Zhuo ZHANG ; Jinlian HE ; Hanren GONG ; Daojun SHEN ; Qun WU
Chinese Journal of Postgraduates of Medicine 2006;0(31):-
0.05). The blood glucose, glycosylated hemoglobin and oxidized low density lipoprotein degrade, insulin resistance were improved in probucol group after treatment, while the adiponectin level was increased(P
4.The use of the hepatoduodenal ligament tension-reduced operation in iatrogenic bile duct injury
Genjun MAO ; Xiaokang WU ; Daojun GONG ; Wei SHEN ; Jianin ZHANG ; Shian YU ; Xuemin LI ; Longtang XU ; Zhangdong ZHENG ; Wenyuan CHENG ; Zhenhua DAI ; Lixia LOU
Chinese Journal of Hepatobiliary Surgery 2011;17(9):749-751
ObjectiveTo investigate the feasibility and efficacy of using the hepatoduodenal ligament tension-reduced operation (tension-reduced operation in short) for iatrogenic bile duct injury where the bile duct was severely defective. MethodsBetween March 2006 and May 2009, the authors treated 6 patients with iatrogenic bile duct injury (Bismuth type Ⅱ : 5 patients and type Ⅲ : 1 patient). A no. 7 black silk thread was used to hold the hilar plate tissues and the seromuscular layer of the bulbous part of the duodenum closer together and knots were tied. This method brought the porta hepatis and the duodenal bulb closer together and the hepatoduodenal ligament was shortened. An end to end anastomosis could then be made between the two broken ends of the defective bile duct without tension. ResultsSix patients suffered from bile duct injury and they recovered fully after the tensionreduced operation. There was no complication on follow-up. ConclusionsThe tension-reduced operation was efficacious in the treatment of iatrogenic bile duct injury. This technique should be popularized and more widely used.
5.Surgical and micro-invasive treatment of pancreatic duct stones: an analysis of 42 patients
Liyuan WANG ; Daojun GONG ; Shian YU ; Xuemin LI ; Xiaokang WU ; Longtang XU ; Genjun MAO ; Rongjin WU ; Bin YANG ; Chi GUO ; Jiamin ZHANG ; Zhangdong ZHENG
Chinese Journal of Hepatobiliary Surgery 2018;24(2):122-123
Pancreatic duct stone is a sequel of chronic pancreatitis and may be found in the main ducts,side branches or parenchyma.These stones obstruct the pancreatic ducts and produce ductal hypertension,which leads to pain,the cardinal feature of CP.Surgical operation has been the preferred treatment of pancreatic duct stones in many domestic and external pancreatic medical centers.Lithotomy by longitudinal pancreatic duct incision and Roux-en-Y anastomosis of pancreatic duct to jejunum is the main and effective surgical procedure,while micro-surgery was also rational for the treatment of pancreatic duct stones.However,further studies with a larger sample size and longer follow-up duration are needed to improve the surgical technique and verify our initial results.