ObjectiveTo investigate the pattern of nursing management in genesiology. Methods The concrete management methods were improving nurses′ skills, arranging personnel resources reasonably, emphasizing patients′ healthy education, strengthening the management of instruments and following patients on. Results The numbers of IVF and IUI cycles increased from 781 and 185 in 1998 to 1 180 and 503 in 2004 respectively. More than 90% of patients had mastered the knowledge about their ART procedures. The time of finding an old medical history decreased from 10 minutes to 2 minutes. And the follow-up rate increased from 42% to 95%. Conclusion In order to adapt to nowadays requirements of genesiolgy, we should establish a perfect nursing management system , using personnel resources reasonably and improve the nurses′ skills continually.