1.Vesiclectomy for patients of hepatic echinococcosis in Tibet:a report of 80 cases
Zhide ZHOU ; Dangsheng LI ; Shunzhou PENG
Chinese Journal of General Surgery 2001;0(09):-
ObjectiveTo discuss problems derived from operative treatment for liver echinococcosis.MethodEighty cases of vesiclectomy with different additional procedures were reviewed with respect to their efficacy or complication. ResultsThere was no mortality in all the patients undergoing various operations. Abscess developed in 6 out of 26 cases undergoing simple vesiclectomy. Two out of 52 cases undergoing "vesiclectomy coupled with tube drainage" suffered bile leakage, while there was no complication in 2 cases undergoing "vesiclectomy plus Roux en Y type vesicajejunostomy". ConclusionVesiclectomy plus tube drainage is the procedure of choice for the treatment of liver echinococcosis.
2.The correlation of epicardial adipose tissue thickness and atrial fibrillation by echocardiography
Meiqing, ZHANG ; Yue, LI ; Qiushuang WANG ; Yanan, ZHAI ; Liqun, WEI ; Dangsheng, HUANG
Chinese Journal of Medical Ultrasound (Electronic Edition) 2017;14(3):186-192
Objective To investigate the association between atrial fibrillation (AF) and epicardial adipose tissue (EAT) by echocardiography.Methods One hundred and thirty-eight patients of AF in First Affiliated Hospital of Chinese People's Liberation Army General Hospital from March 2014 to June 2016 were divided into two groups,including paroxysmal AF group with 87 casesand persistent AF group with 51 cases,and 112 cases of sinus rhythm were chosen as control group.Epicardial adipose tissue was measured using echocardiography in all patients,and the conventional parameters were recorded.One-way analysis of variance was used to compare the thickness of EAT in patients with paroxysmal AF group,persistent AF group and sinus rhythm group,and LSD-t test was used in further comparison between two groups.Multivariable logistic regression analysis was used to analyze the risk factors of AF.The receiver-operating characteristic (ROC) cure of EAT and left atrium diameter (LAD) were drawn to predict the incidence of AF.The correlation between EAT thickness and LAD was analyzed by Pearson correlation analysis.Results The thickness of EAT in patients with persistent AF,paroxysmal AF and sinus rhythm group were (4.75± 1.83),(4.32 ± 1.76) and (1.38 ± 0.68) mm,respectively.Epicardial adipose tissue was significantly larger in paroxysmal AF and persistent AF patients compared with that of sinus rhythm group,and the differences were statistically significant (t=-9.541,11.439,both P < 0.01).Logistic regression analysis indicated that EAT thickness and LAD were independent risk factors of atrial fibrillation (odds ratio:3.17,95% confidence interval:1.31-7.68,P < 0.01;odds ratio:2.65,95% confidence interval 1.69-4.15,P < 0.05).The area under the curve (AUC) of EAT and LAD to predict presence of AF were 0.784 and 0.865,and the best threshold value were 4.45 mm and 40.00 mm,respectively.Pearson correlation analysis showed that the EAT thickness and LAD had significantly positive correlation (r=0.512,P < 0.01).Conclusions The increase of EAT thickness is significantly correlated with the incidence of AF and is independent to traditional risk factors.Therefore,the increase of EAT thickness has certain clinical value to predict AF.
3.Clinical and coronary angiographic features of non-Q wave myocardial infarction in the elderly
Yunfeng XIA ; Beijie LUO ; Runmei LIU ; Hongxia ZHAI ; Yaxi YIN ; Dangsheng HUANG ; Pingsheng LI
Chinese Journal of Geriatrics 2000;0(06):-
Objective To evaluate the clinical and coronary angiographic features of non-Q wave and Q wave myocardial infarction in the elderly. Methods The clinical history(including hypertension and diabetes), complication and in-hospital mortality, blood lipid, serum CK-Mb, LVEF, and the record of the coronary stenosis by angiography 3-4 weeks after infarction were investigated in non-Q wave and Q wave myocardial infarction patients. Results The clinical history and blood lipid did not differ significantly between the NQMI and QMI patients. NQMI patients had a significantly lower maximal peak 〔(68.7?18.6) mmol/L vs (108.6?17.3)mmol/L, P0.05), but occlusion rate of infarct-related vessels in NQMI patients were lower. Conclusions Prognosis of NQMI patients is better than that of QMI patients in acute-phase, and the occlusion rate of infarct-related vessels in NQMI patients were lower.
4.Quality control and quality assurance of single photon emission computed tomography/computed tomography ( SPECT/CT) system
Yihua LIANG ; Weiwu QIN ; Jian YE ; Dangsheng LI ; Zhangwei LUO ; Liyan DENG ; Miao HUANG
Chinese Journal of Primary Medicine and Pharmacy 2010;17(19):2600-2602
Objective To investigate the quality control and quality assurance of the SPECT/CT system.Methods The energy peak,energy resolution capacity and the intrinsic uniformity of the device's detector were regularly examined, and the quality control was performed. Results The daily hardware maintain could reduce the rate of system's trouble. The device's energy peak,energy resolution capacity were consistent during half year's observation period. The two detector's intrinsic uniformity were better after calibration than before. [ detector Ⅰ: ( 2.71 ± 0.28 ) vs (2.37±0.11)(t=2.489,P<0. 05);detector Ⅱ:(2.68 ±0.12)vs(2.38 ±0. 19)(t =6.421,P <0.01) ] .Conclusion Regular quality control and maintain could keep the function stabilization,enhance the availability rate of the SPECT/CT system.
5.Tibetan patients with essential hypertension caused by underlying oxidative metabolism dysfunction and depressed nitric oxide synthesis.
Dangsheng LI ; Xiongwei WANG ; Zhongming FU ; Jun YU ; Wenli DA ; Shunzhou PENG ; Xiangui WANG
Chinese Medical Journal 2003;116(2):309-311
OBJECTIVETo assess the role of oxidative metabolism and nitric oxide synthesis for elucidating their pathophysiological mechanisms in a Tibetan patient with essential hypertension.
METHODSThe serum levels of total superoxide dismutase (T-SOD), malondialdehyde (MDA), total antioxidant capacity (T-AOC), nitric oxide (NO) and nitric oxide synthase (NOS) were assayed in sixty native Tibetans (thirty hypertensive patients and thirty healthy volunteers as control).
RESULTSThe levels of T-SOD, T-AOC, NO and NOS were significantly lower in the patient group than in the control group (P < 0.01); MDA was significantly higher in the patient group than in the control group (P < 0.01). The level of MDA had a strong negative correlation with T-SOD, T-AOC, NO and NOS (r = -0.82, -0.76, -0.79, -0.73, respectively, P < 0.001 for all).
CONCLUSIONTibetan patients with essential hypertension (EH) may have underlying oxidative metabolism dysfunction and depressed NO synthesis, both responsible for the hypertensive process.
Adult ; Altitude ; Endothelium, Vascular ; physiology ; Female ; Humans ; Hypertension ; etiology ; Male ; Middle Aged ; Nitric Oxide ; biosynthesis ; Oxidation-Reduction ; Tibet
6.Diagnostic value of whole body bone scintigraphy combined with tumor markers for bone metastases of non-small cell lung cancer
Hua CHAI ; Linlin WEI ; Zhi YANG ; Ning LI ; Guangxing LIAO ; Hongyu YANG ; Dangsheng LI ; Guoyou XIAO
Chinese Journal of Clinical Oncology 2018;45(12):628-632
Objective: To explore the diagnostic value and efficiency of using whole body bone scintigraphy (WBS) combined with the levels of tumor markers to evaluate non-small cell lung cancer (NSCLC) patients with bone metastases. Methods: One-hundred and eighty-five cases of NSCLC, confirmed by pathology or cytological examination from January 2014 to June 2016, were emrolled from the Affiliated Tumor Hospital of Guangxi Medical University. WBS and test results of tumor markers, such as serum carcinoembryonic antigen (CEA), serum carbohydrate antigen (CA125), and cytokeratin CK19 (CYFRA21-1), were analyzed. WBS results were assessed by the Soloway classification criteria and divided into four grades: Correlations between WBS classification and the levels of tumor mark-ers were determined with Spearman correlation analyses. Results: Seventy-eight of the 185 NSCLC patients had bone metastases (a rate of 42.16%). The sensitivity and specificity of WBS were 91.02%(71/78) and 85.98%(92/107), respectively. The CEA, CA125, and CYFRA21-1 levels in bone metastases patients were higher than those in NSCLC patients without bone metastases (P<0.05). In the 78 patients with bone metastases, there were seven cases of EOD0 (8.98%), 39 cases of EOD1 (50%), 17 cases of EOD2 (21.8%), and 15 cases of EOD3 (19.2%). The correlations between WBS grade and CEA, CA125, and CYFRA21-1 levels were: rs=0.579, 0.274, and 0.327, respectively (P<0.05). The combined WBS and tumor marker diagnostic performance was significantly better than either alone (AUC=0.922), and their sensitivity and specificity increased (92.3%and 86.0%, respectively). Conclusions: WBS shows high clinical efficacy in the diagnosis of NSCLC with bone metastases. Furthermore, it can be used as a screening test for bone metastases of NSCLC, which has important clinical implications. WBS combined with CEA, CA125, and CYFRA21-1 examination improves the detection rate of NSCLC bone metastases, thereby enhancing its clinical utility.