Objective:In order to discuss the influence of processed methods to the contents of total saponins and asperosaponin Ⅵ in Dipsacus asperoids,the content alternation of total saponins and asperosaponin Ⅵ in crude and processed Dipsacus asperoids was investigated.Methods:The content of total saponins was determined by spectrophotometry using vanillin-acetic acid-perchloric acid as the chromogenic reagent.The content of asperosaponin Ⅵ in crude and processed Dipsacus asperoids was determined by HPLC.Results: Contracted to the crude Dipsacus asperoids,the content of total saponins in the processed is higher.The content of asperosaponin Ⅵ in the processed Dipsacus asperoids is higher than that in the crude significantly.Conclusion:Different processed mothods affected the content alternation of asperosaponin Ⅵ in Dipsacus asperoids.The processing of Dipsacus asperoids is reasonable.

Objective To accesse the psychological situation of Gastroscopiers. Methods Questional investigation face to face had been done to some gastroscopiers by using SCL-90 chart and the results were comapred to the common model. Results There were no obviously diaappiontment between the results of the gastroscopiers’and the common model. In total fraction , total average fraction and all kinds of elements which proved the normal psychological health of these people. That was to say that it’s not the gastroscopyical check who has caused the supper stimulaion or substaintial passive emotion although more bitterness. Conclutions The psychological situation of Gastroscopiers is basical normal.

Objective: To find an effect approach to solve the problem on the management of clinic charge bill. Methods:According to the actual working conditions, it suggests we should enhance the management of clinic charge bill form the attitude, system and measures. Results:According to the method and the microcomputer management referred by this article, the management of outpatient charges and bills will be more effective. Conclusion:The management of outpatient charges and bills should be regarded as an important part of the hospital management, and the microcomputer monitoring management should be used to strengthen and improve the management level.

Pediatric knowledge was not fully learned by seven-year program medical students of pediatrics major in first five years,so two years of postgraduate was the key period for culturing their pediatric specialty.Students of seven-year program were characterized by strong theoretical knowledge but poor pediatric clinic knowledge,therefore,pediatric clinic teaching should emphasize on basic knowledge and skills,avoid dwelling on specific details at early stage,pay attention to their communicative ability with children and their relatives,combine theory with clinic practice and teach from surface to point.Meanwhile,we aimed at changing them into pediatric doctor through cultivating their clinic skills and scientific research ability.

Under the high pressure of employment, traditional teaching method that is based on inculcating the knowledge to students does not adjust current condition any more. So, we start to looking for a new, more suitable way of teaching.--Project Based-on Learning, and have analyzed the advantages in health information technology teaching by construction doctrine in combination with the concept and principle in wedlock construction. At the same time we introduce project Based-on Learning in concrete application to find a way to put the theory into practice.

Objective: To improve the standardization method for ethanol potassium hydroxide volumetric solution. Methods: A new potentiometric titration method was established and compared with the indicator method described in Chinese Pharmacopeia (2010 edition) . Results:There was no significant difference between the results of the potentiometric method and the indicator method( P>0. 05). Furthermore, the potentiometric titration had significant jump range, good precision and high reliability. Conclusion:The po-tentiometric method can be used in the standardization of ethanol potassium hydroxide volumetric solution.

AIM: To investigate the protective mechanism of Danggui Buxue Decoction(Radix Astragali,Radix Angelieae Sinensis) on the kidney of diabetic rats. METHODS: The diabetic animal model was made by a single intraperitoneal injection of 60 mg/kg streptozotocin(STZ) and treated with Danggui Buxue Decoction(DBD) or Benazepril. Renal weight/body weight ratio, blood glucose and lipid, urinary albumin and ? 2-microglobin were measured. The renal pathological lesions were also investigated. The expression of TGF-? 1 mRNA in renal cortex as well as Angiotensin Ⅱ(AngⅡ) concentration of plasma and kidney tissue were determined by In situ hybridization and radioimmunoassay after 4,8 weeks of treatment. RESULTS:DBD had equivalent effects with Benazepril in protecting renal function and alleviating pathologic lesions. By means of inhibiting the expression of of TGF-? 1 mRNA. DBD had no effect on renal and plasmaAngⅡ. CONCLUSION:Danggui Buxue Decoction may alleviate kidney lesion and slow down the progression of DN by decreasing the renal expression of TGF-? 1 mRNA.

Pemetrexed is a multitargeted anti-metabolite.Pemetrexed has been approved as first-line treatment in malignant pleural mesothelioma(MPM)and second-line treatment in non-small cell lung cancer(NSCLC).A lot of experimental and clinical trials on pemetrexed have been conducted for the treatment of several kinds of cancer now.This paper summarizes the current developments in experimental and clinical research.

Lentinan could enhance the proliferative response of the mouse spleen lymphocytes to FHA, LPS ( Lipopolysaccharides ) and MLR ( Mixed Lymphocyte Reaction ) in vitro in a concentration-dependent manner. At the concentration of 25M-g/ml, it had the most prominent effects and the enhancing rates were 42.1%, 24.1% and 27.1% respectively. At much higher or lower concentrations, however, it had almost no effects. But lentinan at 25H-g/ml could inhibit the prolifera-tire response to Con A ( Concanavalin A ) and the inhibitory action increased with the increase in the concentration. At the concentration of 200 p-g/ml, the inhibition rate was 52.2%.

It has been reported that bimolane can inhibit either humoral or cell-mediated immunological responses in vivo in mice & the inhibition of humoral immunity (by bimolane) is stronger than that of cellular immunity. Author investigated the influence of bimolane on the mitogen-induced mouse lymphocyte proliferation. Bimolane inhibited the lymphocyte proliferation induced by Con A(concana-valin A), PHA ( phy tohemagglutinin ) or LPS(lipopoiysaccharide) . Bimolane dose-dependently inhibited LPS-induced lymphocyte proliferation with remarkable inhibition at 1.56 mg/L bimolane. The inhibition of Con A-induced or PHA-induced lymphocyte proliferation by bimolane, however, began to appear at above 6.25 mg/L bimolane. The bimolane-mediated inhibition of the proliferation of the lymphocytes was not due to a nonspecific toxicity, because the preincubation of spleen cells with 25 mg/L bimolane for 24h did not make the cells died tested by trypanblau exclusion method.The data suggest that B lymphocytes are more sensitive to the bimolane-mediated inhibition than T lymphocytes.