Teaching quality is the basis of higher education.This article compared the results of teaching supervision and evaluation between campus and affiliated hospitals of Qiqihar Medical University in 2011.Differences were found out and corresponding strategies were proposed in order to improve the teaching quality and train high-quality talents.

Objective To evaluate the difference of the level of erythropoietin (EPO) in primary open-angle glaucoma (POAG),pseudo exfoliative glaucoma (PXFG),and neovascular glaucoma (NVG).Methods One hundred glaucoma patients and 30 single cataract patients (control group) without other ocular region disease and systemic disease were enrolled in this study.In glaucoma patients,POAG was 40 patients (POAG group),PXFG was 30 patients (PXFG group),NVG was 30 patients (NVG group).The level of EPO in aqueous humor was measured by double antibody sandwich enzyme-linked immunosorbent assay.Results The level of EPO in POAG group,PXFG group,NVG group,control group was (19.1 ±5.6),(18.8 ± 6.5),(142.7 ± 20.6),(0.9 ± 0.5) U/L.The level of EPO in POAG group,PXFG group,NVG group was significantly higher than that in control group,the level of EPO in NVG group was significantly higher than that in POAG group and PXFG group (P＜ 0.01).But the level of EPO between POAG group and PXFG group had no significant difference (P ＞ 0.05).The level of EPO in PXFG group with intraocular pressure control patients was lower than that in POAG group with intraocular pressure control patients [(14.6 ± 1.4) U/L vs.(18.5 ± 6.2) U/L],the level of EPO in PXFG group with intraocular pressure nocontrol patients was higher than that in POAG group with intraocular pressure no-control patients [(28.5 ±10.7) U/L vs.(19.2 ± 6.4) U/L],there was significant difference (P ＜ 0.05).In PXFG group,the level of EPO had positive relationship with intraocular pressure (P ＜ 0.05).The level of EPO in NVG group with intraocular pressure control and no-control patients was higher than that in POAG group and PXFG group with intraocular pressure control and no-control patients,there was significant difference (P ＜ 0.05).Single factor analysis showed that intraocular pressure,type of glaucoma had correlation with the level of EPO (P ＜0.01).Multiple factors analysis showed that type of glaucoma was the main effective factor of the level of EPO (P ＜ 0.01).Conclusions The level of EPO in POAG,PXFG and NVG patients is higher than that in single cataract patients.The associativity between the level of EPO and intraocular pressure in PXFG patients is higher than that in POAG and NVG patients.

Objective Working memory (WM) is one of important cognitive functions.The aim of this study was to investigate spatial distributions of electroencephalographs (EEGs) power during visual WM task,which may provide support for studying the principal frequency band and critical region related to WM.Methods 32-channel EEGs were recorded from 16 healthy subjects while they perform visual WM task.The data came from 240 trials and the original EEGs were preprocessed.Fourier transform was applied to calculate spatial distributions of EEGs power in the δ,θ,α,β,γfrequency bands and the percentage of each band in the total power.Results The percentages of δ,θ,α,β,γbands in the total power were (22.44±0.86)％,(31.88±0.55)％,(24.66±1.43)％,(13.54±0.64)％,(7.47±0.48)％,respectively.The power in the θ band was significantly higher than those in the other bands (paired t-test,P＜0.001).The θ power was focused in the frontal midline region.Conclusions The principal frequency band related to WM was the θ band and the critical region was the frontal region.

Abstract?AlM:To investigate effect and safety of the limbal stem cell transplantation combined with low concentrations of mitomycin C for pterygium patients with type 2 diabetes mellitus (T2DM).? METHODS: Eighty patients of 96 pterygium eyes admitted to hospital were divided into groups of high concentration, low concentration group and the control group, and 3 groups were given pterygium excision combined with limbal stem cell transplantation. The high concentration group, the low concentration groups were given prior to stem cell transplantation 0. 2, 0. 1mg/mL mitomycin C coverage. The cure rate and recurrence rate in three groups of patients, as well as visual acuity before and after treatment were compared.?RESULTS: Three groups patients' visual acuity were significantly improved after treatment (P<0. 05), there was no significant difference before treatment in visual acuity (P>0. 05);epithelial healing time of high concentration group was significantly higher than low concentration group and the control group (P<0. 05), there was no significant difference between low concentration and control groups of epithelial healing time (P>0. 05); cure rates of low concentration group was higher than high dose group, the recurrence rate in low concentration group was lower than the high dose group.? CONCLUSlON: Pterygium excision combined with limbal stem cell transplantation has significant efficacy for pterygium, and mitomycin C can effectively reduce the relapse rate, but for the patients with T2DM concentration of mitomycin C should be reduced.

Objective To investigate the expression of insulin-like growth factor-binding protein-5( IGFBP-5) in full-term rats with hyperoxia-induced chronic lung diseases(CLD) and its mechanism.Methods Ninety-six full-term rats were randomly exposed to hyperoxia (hyperoxia group)and room air(room air group).CLD was induced by hyperoxia exposure.RT-PCR and immunohistochemical metho -ds were used to detect the expression of IGFBP-5 at 1,3,7,10 ,14 and 21 days after exposure.Results The expression of IGFBP -5 was dynamic, the expression of IGFBP-5 increased significantly in hyperoxia group compared with room air group at 3 d to 10 d after hyperoxia exposure (P

Objective: Crude Leonuri Fructus (CLF), the fruits of the Leonurus japonicus Houtt, and processed Leonuri Fructus (PLF) by stir-baking as the important Chinese herbal medicines, have been used in China and other Asian countries for thousands of years. The objective of this research is to reveal the difference between CLF and PLF. Methods: The sensory technologies of the colorimetry, sensitive and validated HPLC-ELSD and GC combined with flame ionization detector (GC-FID) were employed to discriminate CLF and its processed product PLF. The color parameters of the samples were determined by colorimetric instrument CR-410. Moreover, the content of stachydrine and six fatty acids were determined by HPLC and GC. Subsequently, analysis of variance (ANOVA), principal components analysis (PCA), hierarchical cluster analysis (HCA), and Kendall's correlation test were performed for data analysis. Results: The CLF and PLF were divided into two categories by PCA and HCA in terms of their component content and color. The results distinctly demonstrated significant changes in color and the content of indicative components between CLF and PLF. Conclusion: The study revealed that HPLC, GC, and colorimetric method in combination with chemometric method could be used as comprehensive quality evaluation for CLF and PLF.

Synovial sarcoma is a rare tumour found in soft tissue; it is a mesenchymal spindle cell tumour that is not related to the synovial membrane. This tumour has a low incidence, and the most frequent place of occurrence is the lower extremities in young adults. Synovial sarcoma of the head and neck accounts for 3%-5% of sarcomas in this anatomical region. The tumor in the nasal cavity is less than 1%. The treatment of choice for synovial sarcoma of the head and neck is complete surgical excision of the tumour mass followed by adjuvant radiotherapy.
Humans ; Nasal Cavity ; pathology ; Nose Neoplasms ; diagnosis ; radiotherapy ; surgery ; Paranasal Sinuses ; pathology ; Radiotherapy, Adjuvant ; Sarcoma, Synovial ; diagnosis ; radiotherapy ; surgery

OBJECTIVE: To investigate the characteristics and causes of adverse drug reactions (ADR) in Jiangxi region in order to improve the rational use of drug in clinic. METHODS: A total of 10 033 cases of ADR reports collected in Jiangxi region in 2008 were classified and analyzed statistically. RESULTS: The ADR were predominantly induced by antimicrobial drugs (53.76%), followed by TCM preparation (16.68%). Intravenous administration was the main cause of ADR(65.45%). 225 case of severe ADR reports accounted for 2.24% and 412 cases of new ADR reports 4.11%. 99 cases of severe ADR were characterized by the systematic damages.12 death cases and 12 sequelae cases were involved in 225 cases of severe ADR reports. CONCLUSION: Great importance should be attached to ADR monitoring, reporting and publicizing to promote rational use of drug in clinic.

Objective To observe the clinical efficacy of scalp acupuncture plus acupuncture at Jiaji points (EX-B 2) in treating chronic fatigue syndrome (CFS).Method Seventy CFS patients were randomized into a treatment group and a control group, 35 cases in each group. The treatment group was intervened by scalp acupuncture plus acupuncture at Jiaji points (EX-B 2), while the control group was by ordinary acupuncture. The Fatigue Scale (FS)-14 was observed before and after treatment, and the clinical efficacies were compared.Result The FS-14 scores were significantly changed after treatment in both groups (P<0.01). After treatment, the FS-14 score of the treatment group was significantly different from that of the control group (P<0.05). The total effective rate and recovery-markedly-effective rate were respectively 91.4% and 71.4% in the treatment group, versus 82.9% and 45.7% in the control group. There was a significant difference in comparing the recovery-markedly-effective rate between the two groups (P<0.05).Conclusion Scalp acupuncture plus acupuncture at Jiaji points (EX-B 2) is an effective method in treating CFS.

Objective To observe the effects of exercise training on the expression of glycogen synthase ki-nase-3 (GSK-3) in the skeletal muscles of rats with insulin resistance induced by a high-fat and high sucrose diet. Methods Thirty Wistar rats were randomly divided into three groups: a control group, a model group and an exercise group. Rats in the model and exercise groups were fed with a high-fat and sucrose diet (20% sucrose, 10% lard, 2.5% cholesterol, 1% cholic acid) for 4 weeks, and then the rats in the exercise group were trained by swimming 5 d every week for 6 weeks. After treatment, the concentration of GSK-3 protein in their muscles was detected by Western blot analysis, while their weights, serum triglyceride and total cholesterol, and their concentrations of fasting plasma glucose and fasting plasma insulin were measured periodically and their insulin sensitivity index was calculated. Results Compared with the controls, the expression of GSK-3 in the skeletal muscles of the rats in the model group increased by 70. 20% (P