Objective To compare the effects of two different approaches of insulin delivery on hyperglycemia.Methods 26 poorly controlled diabetic patients were studied by two methods of intensive insulin delivery.⑴Continuous subcutaneous insulin infusion(CSⅡ) group(n=6),including 4 cases of type 1 DM,2cases of type 2 DM;⑵Multiple subcutaneous insulin injection(MSⅡ) group(n=20),including 3 cases of type 2 DM,17 cases of type 2 DM.The target BGs for both groups were premeal and bedtime BG3≥3 6mmol/L ≤7 2mmol/L for at least 3 days.Results Both groups had reached the target BGs,the CSⅡ groups more close to normal level.The average durations of treatment were significantly different;CSⅡ(8 3?1 3)d,MSⅡ(13 6?2 4)d for the two groups (t=5 136,P0 05).The hypoglycemia incidence in CSⅡ was(0 67?1 3)time/case,in MSⅡ(2 15?1 4)time/case(t=2 305,P