1.Decomposition of Air Organic Pollutants by Nano-materials:a review
Journal of Environment and Health 2007;0(09):-
The organic pollutants in the air is so harmful to human health and is difficult to be degraded.However,to degrade the organic pollutants with nano-materials by photocatalysis reaction can get a good effect.The basic principle of photocatalysis reaction of the nano-materials was explained and the different degradation effects for organic pollutants were compared in this paper.The application of nanosize TiO_2 was briefly described and meanwhile the affecting factors and the methods to improve the catalysis efficiency were discussed.
2.Application of dental operative microscope in detecting the mesiobuccal root canal orifice of the maxillary first permanent molar
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(04):-
Objective To observe the effect of the dental operative microscope(DOM) and the ultrasonic apparatus in detecting the mesiobuccal root canal orifice of the maxillary first permanent molar(MFPM). Methods According to traditional method,the pulp chamber was opened and the second mesiobuccal root canals(MB2) were explored in 76 MFPM teeth.If MB2 was not found,then we modified the shapes of the pulp chambers and detected the orifices.At last,MB2,not found under naked eyes,was explored with DOM and ultrasonic technique. Results The detection rate of the second mesiobuccal orifice of MFPM was 81.6%.The rate was only 31.6% when using traditional method,while after modifying the shapes of the pulp chambers there was an increase of 30.2% under naked eyes and then another 19.7% increase was obtained by using DOM and ultrasonic apparatus.The distance between two mesiobuccal root canal orifices was(1.42?0.51) mm. Conclusion It is helpful to find some invisible orifice of MB2 by using DOM and ultrasonic technique,and it would be beneficial to improve the root canal therapy.
3.Content Determination of Paeoniflorin and Liquoritin in Jiawei Xiaoyao Pills by HPLC
China Pharmacy 2015;(18):2571-2572
OBJECTIVE:To establish the HPLC method for the content determination of paeoniflorin and liquoritin in Jiawei xiaoyao pills. METHODS:It was performed on Hypersil-ODS C18 with the mobile phase of acetonitrile-water(14∶86,V/V)at the flow rate of 1.0 ml/min,the detection wavelength was 230 nm,the column temperature was room temperature and the volume was 10 μl. RESULTS:The linear range was 16.12-80.6 μg/ml for paeoniflorin(r=0.999 6)and 6.08-30.4 μg/ml for liquoritin(r=0.999 8);the RSDs of precision,repeatability and stability tests were all less than 2.0%;the average recovery was respectively 98.51%(RSD=1.94%,n=6)and 98.08%(RSD=1.29%,n=6). CONCLUSIONS:The method is simple,accurate and reliable, and can be used for the content determination of paeoniflorin and liquoritin in Jiawei xiaoyao pills.
4.Analysis of Antiepileptic Drugs in6Children's Hospitals in the Yangtze Valley during the Period of2002~2004
China Pharmacy 2001;0(11):-
OBJECTIVE:To evaluate the status quo and the tendency of antiepileptic drugs used in6Children's Hospitals in the Yangtze Valley.METHODS:Data on drug variety,sales volume,manufacturers of antiepileptic drugs used in6Chil?dren's Hospitals in the Yangtze Valley during2002~2004were analyzed statistically.RESULTS:Sodium valproate and topi?ramate took a bigger share in the market with the proportion of both to the antiepileptic drugs in sales volume at about40%.The old variety still took the lead in the clinical drug consumption while the momentum for the consumption of new one was quite fine.CONCLUSION:There are only a few varieties of antiepileptics now yet the sales volume of which is on the rise,therefore,of which there is still prospect of development.
5.Study on Bioequivalence of Domestic Oxcarbazepine Dispersible Tablets
China Pharmacy 2005;0(18):-
OBJECTIVE: To study the bioequivalence of domestic oxcarbazepine dispersible tablets. METHODS: 20 healthy male volunteers were randomly given oxcarbazepine dispersible tablets (test tablet) and oxcarbazepine tablets (reference tablet) via p.o. The plasma concentration of active metabolite (MHD) of oxcarbazepine were determined by HPLC. 3p97 software was used to calculate pharmacokinetic parameters and the bioequivalence of oxcarbazepine were evaluated. RESULTS: After treatment main pharmacokinetic parameters of test tablet vs. reference tablet were as follows: Cmax(4.231?0.841) ?g?mL-1 vs. (4.350?0.861) ?g?mL-1; tmax(4.13?0.43) h vs. (4.28?0.44) h; t1/2(14.17?2.66) h vs. (14.44?2.09) h; AUC0~60 (113.00?22.25) mg?h?L-1 vs. (118.11?14.20) mg?h?L-1; AUC0~∞(126.35?20.94) mg?h?L-1 vs. (130.54?16.17) mg?h?L-1. The relative bioavailability of test tablet to reference tablet was (95.67?12.80)%. CONCLUSION: Two kinds of tablets were bioequivalent.
6.Choroidal hypoperfusion associated with photodynamic therapy for choroidal neovascularization
Chinese Journal of Experimental Ophthalmology 2013;31(8):788-791
Choroidal neovascularization (CNV) ithe leading cause of vision disordecaused by variouretinal diseases.Apresent,many therapeutimethodare employed clinically,such aphotodynamitherapy (PDT),anti-vasculaendothelial growth facto(anti-VEGF) and transpupillary thermotherapy (TTT).However,none of them can cure CNV thoroughly and repeated treatmenirequired usually.The reason forecurrenCNV istill unclear.Choroidal hypoperfusion associated with Pdmay be one of the reasons.The purpose of thireview ito discusthe problem of choroidal hypoperfusion associated with PDfoCNV awell aitimpacon the eye and possible solutions.Thipapepresentevidenceof choroidal hypoperfusion aftePDand itrelationship with clinical outcomes.Meanwhile,the effecof combination therapy iassessed.Finally,low-fluence Pdirecommended apotential method to reduce choroidal hypoperfusion.
7.Effect of safflower on renal interstitial fibrosis and renal function in rats
Rong-TANG ; Shen-Hua DU ;
Chinese Journal of Clinical Pharmacology and Therapeutics 2000;0(03):-
AIM:To research the effect of safflower in renal intertistial fibrosis by GFR and renal biopsypathology with Sprague-Dnwley(SD) rat model.METHODS:All rats were distributed into 6 groups.Group A was normal control,group B received sham operation,group C was vehicle control,group D received vehicle,group E received safflower(10(g?kg~(-1)) body(wt?d~(-1))),and group F received enalapril((12.5)(mg?kg~(-1)) body(wt?d~(-1))).Rats underwent reversible left renal vein obstruction for 6 d,after which the obstruction was relieved.Renal function was determined by measuring GFR with inulin clearances.Both renal tubular epithelial cells(RTECs) and fibronection deposition for renal interstitial fibrosis were identified by immunohistochemistry.The positive and negative areas of per slice was determined by a motic medical 6.0 graphical analytical system.Atrophic tubules were determined by measuring the tubule diameter.10 fields per slice were analyzed at ?400 magnification.RESULTS:Return of glomerular filtration rate(GFR) was seen in group E and goup F,which was significantly better than group D(P
9.Influence of Optimized Nursing Process on the Clinical Effect and Quality of Life of Patients with Cerebral Infarction Received Intravenous Thrombolysis
Bizhi XU ; Rong DU ; Xiaocui WU
Journal of Kunming Medical University 2016;37(12):144-147
Objective To observe the influence of optimized nursing process on the clinical effect and quality of life of patients with cerebral infarction received intravenous thrombolysis.Methods Sixty-two cerebral infarction patients with thrombolytic therapy in Panzhihua Central Hospital were treated as control group from January 2013 to June 2014,74 cases cerebral infarction patients with thrombolytic therapy as the observation group from July 2014 to October 2015.The control group received routine nursing,the observation group were given optimized nursing process on the basis of routine nursing.The clinical effect and quality of life were compared between the two groups.Results The triage time,referral time and hospital stay time of the observation group were significantly shorter than the control group,the differences were statistically significant (P <0.05).The effective rate in the control group was 70.97%,that of the observation group was 87.84%,the effective rate in observation group was significantly better than that of the control group,the difference was statistically significant (P <0.05).Compared with before treatment,the life quality of two groups were significantly improved after treatment,the difference was statistically significant (P<0.05);after treatment,the quality of life in observation groups were better than that of the control groups,the difference is statistically significant (P<0.05).Conclusion Nursing process optimization can effectively improve the therapeutic effect for the patients with cerebral infarction intravenous thrombolytic therapy,shorten the treatment time and hospitalization time,and can significantly improve the patient' s quality of life.It is valuable for clinical application.
10.Comparative Analysis on Contents of Phenolic Acids in the Decoction of Xanthii Fructus before and after Frying
Rong DU ; Li REN ; Mengyou ZHANG
China Pharmacist 2016;19(2):247-250
Objective:To examine the content changes of neochlorogenic acid, chlorogenic acid, 1, 5- dicaffeoylquinic acid and total phenolic acids in the water extract from raw and fried Xanthii Fructus. Methods:The stir-frying method was used to process fried Xanthii Fructus from different habitats. The contents of neochlorogenic acid, chlorogenic acid and 1,5-dicaffeoylquinic acid in the wa-ter extract were determined by HPLC, the total phenolic acids content was determined by UV. Results:The contents of neochlorogenic acid, chlorogenic acid, 1,5-dicaffeoylquinic acid and total phenolic acids in the water extract from fried Xanthii Fructus were all in-creased. Conclusion:Fried Xanthii Fructus can increase the contents of effective ingredients in the decoction resulting in the enhanc-ment of clinical curative effect.