Objective:To investigate the relationship between microalbuminuria(MAU)and obesity in Chongqing natives.Methods: Four hundred and seventy eight subjects over 30 years old were selected at random from health examination population.They were divided into 3 groups according to the Body Mass Index(BMI)diagnostic standard of〈The Guide of control and prevention of overweight and obesity in Chinese aduhs〉,control group(Con group),over weight group(Ow group)and obesity group(Oh group).MAU were tested in all groups and invested with every item in Ob group.Results:The prevalences of over weight and obesity in the present study were 40.0% and 7.3% respectively.The MAU in Ob group was more than that in Con group (P

Objective To explore the clinical curative effect of central venous catheter drainage in treating pleural effusion.Methods 100 cases with pleural effusion were treated by the central venous catheter drainage.The curative effect,complications and adverse reactions were observed.Results Ater treatment for 12 ～ 28d,catheter drainage of 100 patients were all successful at the first time.The clinical effect:completely relieve 40 cases(40.0％),clinical partial remission 47 cases(47.0％),inefficient 13 cases (13.0％),and the total effective rate was 87.0％.There were some complications:pneumothorax 1 case,hemorrhage 2 cases,infection 1 case,pleural reaction 3 cases,pain 3 cases,subcutaneous emphysema 2 cases and take off the tube 1 case,the incidence rate of complications was 13.0％.Conclusion Central venous catheter drainage in t.reating pleural effusion has significant curative effect,which is worthy of clinical application.

Objective To make a method to determine trace iron (FeⅢ)in human hair. Methods Based on the coloured reaction between XO and Fe(Ⅲ)in the medium of HAc-NaAc(pH=3.2)with the presence of OP, FeⅢ was determined by spetrophotometry. Results It was found that when pH=3.2 and in the presence of OP, iron(Ⅲ) reacted with XO to form a stationary complex. The maximum absorption wave of Fe(Ⅲ)-XO was 570 nm, as OP was added, it moved to 590 nm, and the sensitivity was increased obviously when the molar absorptivity of the complex reached 3.67?105 L/(mol?cm) from 3.04?104 L/(mol?cm), the linear range for the content of Fe(Ⅲ)was 0.0～0.8 ?g/ml(0.0～20.0 ?g/25 ml), the regression equation of calibration graph was A=0.00236+0.542c(?g/25 ml)with a correlation coefficient of 0.997 6, detection limit was 6.09?10-6 g/L, RSD=0.97% and rate of recovery was 96%-99%. Conclusion The method can be used for the determination of trace iron(Ⅲ)in human hair samples.

OObjective] To explore the version and academic achievements of“Yan Hou Lun”. [Method] Finding of the bibliography of books about the version, one by one to check. And analyse the content of the book, summarize the academic achievement.[Result] There are three versions. This book has written tonsillitis, and other common diseases of throat. Diagnosis of disease, according to the lesion site and colour and lustre. It promotes the use of external power.[Conclusion]It can be divided into two versions of the system. It is a throat book appearing earlier, has a certain clinical practicability.

Multiple myeloma (MM) is the second most common hematological malignancy.In the 56th American Society of Hematology (ASH) annual meeting,there are mainly five hot and key topics focusing on development of MM treatment,including when is the opportunity of transplant-eligible patients in the era of novel therapy? Should continuous therapy be the standard therapeutic approach in MM? What is a practical approach to relapsed MM? How should the recurrence/refractory MM patients be managed and treated? And what are the approved agents and novel agents?

Multiple myeloma (MM) is a genetically complex disease that is becoming more common in today' s aging population.In the 18th European Hematology Association (EHA) annual meeting,there were a number of key topics focusing on the development of MM from intraclonal heterogeneity,novel therapeutic agents,and relapse and refractory MM therapy,etc.

Multiple myeloma is the second most common hematological malignancy.In the 19th European Hematology Association (EHA) conference,there are a number of hot and key topics focused on developing of MM diagnosis criteria,response evaluation,treatment strategy for elderly and relapse/refractory myeloma patients,and maintenance therapy etc.

Primary nephrotic syndrome (PNS) is one of the most common forms of glomerular disorder in chil dren.It is reported that over 90％ of patients are due to minimal change disease and most respond to glucocorticoid (GC) therapy.However,76％-93％ cases have relapses and 40％-50％ frequently relapses nephritic syndrome or steroid dependent nephritic syndrome when steroid is tapered.Long-term courses of GC and immunosuppressant will place them at increased risk for severe side effects.Not all patients do respond to therapy.Although most reports on rituximab use in pediatric patients have not recognized significant side effects,the long-term adverse events of rituximab are not known.Thus,controlled long-term studies are required to be done to assess the risk-benefit profile of rituximab in childhood nephrotic syndrome.

Automated body fluid cytology analysis has been accepted by clinical laboratories gradually.The improvement of efficacy and analytical precision can overcome some defects of traditional manual method,such as time-consuming and poor repeatability.To make use of the advantages of automated fluid cell analysis technology,the automated method and microscopic method must be combined by setting review rules.Meanwhile,more attentions must be paied to sample collection and specimen preservation at pre-analytical stage,verification of instrument performance at analytical stage and necessary clinical communication at post-analytical stage.Only if a complete system of quality management,standardization of procedures,result validation and interpretation is implemented in the routine work,the clinical significance of body fluid cytological analysis can be recognized in clinical practice.

Objective To explore the current therapeutic strategy for community acquired pneumonia(CAP) in the tertiary hospitals in Beijing district,and provide the evidence-based medicine for recommending application of Chinese community acquired pneumonia(CAP) guideline in our country widely.Methods The data of 225 hospitalized CAP patients from July 1st,2002 to June 30,2004 was documented retrospectively. The patient's situation was scored by either Chinese CAP guideline or Fine's risk classification.The data was analyzed with SPSS 10.0 to identify the correlation between the results evaluated by the two guidelines,and the differences of the combining use of antibiotics and antibiotic selection between group 1 and group 2 classified by Chinese CAP guideline.Results There was a significantly statistical correlation between the two guidelines(P=0.0000).There was a significantly statistical difference both in alternative administration of single or combining antibiotics(P=0.0290) and alternative application of penicillin or the third generation of cephalosporins(P=0.0001,P=0.005,respectively) between hospitalized criteria mismatched and matched groups classified by Chinese CAP guideline.The ratio of using fluroquinolone in above two groups was significantly high compared with other reagents,and there was no significant difference between them(P=0.182).Conclusion There is significant correlation between Chinese CAP guideline and Fine's risk classification.Chinese CAP guideline can be used to distinguish CAP from different risk levels.It is necessary to enforce and standardize the CAP diagnosis and treatment guideline widely.