1.Non-Hodgkin’s Lymphoma Masquerading as Psoas Abscess: A Case Report
WM Ng ; TC Ong ; MK Kwan ; CY Cheok
Malaysian Orthopaedic Journal 2008;2(1):49-51
We report here a rare presentation of an extra-nodal non-
Hodgkin’s lymphoma. Both clinical presentation radiological
findings were suggestive of psoas abscess. Surgical
debridement was performed and histopathological
examination of the tissue sample revealed the diagnosis of
non-Hodgkin’s lymphoma. It is therefore important to note
that non-Hodgkin’s lymphoma can mimic psoas abscess and
that psoas lesion with vertebral involvement does not
necessarily indicate infection. It is always advisable to obtain needle biopsy to establish diagnosis before embarking on surgical intervention. The practice to send any suspicious tissue obtained intra-operatively for histopathological examination is also warranted.
2.Cyclopiazonic acid enhanced the Ca~(2+)-dependent outward K~+ currents in cultural aortic smooth muscle cells from SHR and WKY
Yongyuan GUAN ; Zhang JOHN ; Rkw LEE ; Cy KWAN ; Ee DANIEL
Chinese Pharmacological Bulletin 1986;0(04):-
ABSTRACT The effects of cyclopiazonic acid (CPA) on the Ca2+ -dependent ourward K+-cur-rent [IK(ca)] were studied using whole-cell and single-channel patch-clamp techniques. Depolarization (pipette potential range from - 20 to - 120 mV)induced a outward Ik(ca) with a conductance of about 40 pS in the cultural aortic smooth muscle cells from SHR and WKY. 10 ?mol ? L-1 CPA significantly enhanced these currents and prolonged the mean open time of the channels. This effect of CPA was completely blocked by glybenclamide, a K+-channel block-er. In the whole cell recording experiments, CPA increased the amplitude of outward K+-current. This effect of CPA was Ca2+-dependent and completely blocked by glybenclamide. There was no any significant difference between the effects of CPA in SHR and in WKY. These results suggest that the functional change of vascular smooth muscle in SHR doesn't appear to be related to Ik(ca).