1.Value of ~(99m)Tc MIBI scintimammography in the differential diagnosis betwwen benign breast tumor,breast cancer and lymph node involvement
Dasi GUO ; Yuetao WANG ; Cunzhi LU ;
China Oncology 2000;0(06):-
Purpose:To sutdy the clinical value of 99m Tc MIBI scintimammography in the differential diagnosis between breast cancer and benign breast tumor and lymph node involvement. Methods:68 female patients with breast masses underwent 99m Tc MIBI breast scintigraphy. The images were acquired 10 min after injection of 740 MBq 99m Tc MIBI intravenously. The intravenous injection was performed into an antecubital vein in the arm on the side opposite to the breast mass. Results:38 of 68 patients were breast carcinoma, among them 34 were detected using 99m Tc MIBI scintimammography. Of 30 patients with benign lesions, 3 were positive. The sensitivity and specificity of 99m Tc MIBI scintimammography in detecting breast cancer was 89.5% and 90% respectively. 6 of 8 with pathologically proven metastatic lymph node involvement were detected. Conclusions: 99m Tc MIBI scintimammography is a highly sensitive method in the detection of breast cancer. This study also show the potential value of the procedure to detect lymph node mvolvement.
2.Cumulative Analgesic Effect of Electroacupuncture at Sanyinjiao (SP6), Xuanzhong (GB39) and Non-acupoint for Primary Dysmenorrhea:A Comparative Study
Jiashan SONG ; Yuqi LIU ; Cunzhi LIU ; Yanfen SHE ; Jieping XIE ; Yinying CHEN ; Mengmeng WU ; Guangxia SHI ; Yali WEN ; Jingdao LI ; Yuxia MA ; Kun LU ; Linpeng WANG ; Wei ZHOU ; Jingxian HAN ; Shuzhong GAO ; Jiping ZHAO ; Shiliang LI ; Liangxiao MA ; Jianmin XING ; Huijuan CAO ; Jianping LIU ; Jiang ZHU
Shanghai Journal of Acupuncture and Moxibustion 2015;(6):487-492
Objective To compare the cumulative analgesic effects of electroacupuncture at Sanyinjiao (SP6), Xuanzhong (GB39) and non-acupoint in treating primary dysmenorrhea. Method By adopting a multi-centered randomized controlled study method, 501 patients recruited from Dongzhimen Hospital of Beijing University of Chinese Medicine, China-Japan Friendship Hospital, Beijing Hospital of Traditional Chinese Medicine of Capital Medical University, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Huguosi Hospital of Chinese Medicine of Beijing University of Chinese Medicine and the Outpatient of Shandong University of Traditional Chinese Medicine were randomized into a Sanyinjiao group, a Xuanzhong group, and a non-acupoint group, 167 subjects in each group. The electroacupuncture intervention was applied when dysmenorrhea flared up and the Visual Analogue Scale (VAS) ≥40 mm, with frequency at 2/100 Hz and intensity during patient’s endurance, 30 min each time, once a day, and for successive 3 d. Before the first treatment, 30 min after the first treatment, and respectively prior to the second and third treatment, VAS was used to measure the pain intensity. Meanwhile, the Retrospective Symptom Scale (RSS-COX 2) was investigated before the first treatment, right after the removal of needles for the first treatment, before the second and third treatment. Result The decrease of VAS in Sanyinjiao group was more significant than that in Xuanzhong group and non-acupoint group (MD=﹣2.92 mm, P=0.028; MD=﹣3.47 mm, P=0.009), while there was no significant difference between Xuanzhong group and non-acupoint group (MD=﹣0.56 mm, P=0.674); there were no significant differences in comparing the RSS-COX2 total score among the three groups (P=0.086). Conclusion Sanyinjiao (SP6) can produce a more significant cumulative analgesic effect for primary dysmenorrhea patient than Xuanzhong and non-acupoint, and the effects of Xuanzhong and non-acupoit are equivalent.
3.Research progress in molecular mechanism of blast lung injury
Hong WANG ; Junhong GAO ; Wenjuan ZHANG ; Jinren LIU ; Xiaolin FAN ; Cunzhi LI ; Qing LU ; Qingbo KONG ; Airong QIAN
Chinese Journal of Trauma 2020;36(8):749-754
Lung is one of the most sensitive target organs of human beings under the shock waves. Due to its serious injury, rapid development and high mortality, blast lung injury has been a widely concerned research topic in the field of military medicine. In the normal physiological state, the body is in a dynamic balance between pro-inflammaton and anti-inflammation, oxidation and anti-oxidation, promoting apoptosis and inhibiting apoptosis. While blast lung injury breaks the balance and causes physiological, biochemical and pathological changes in the body, seriously leading to acute respiratory distress syndrome and multiple organ dysfunction syndrome, and eventually the mortality. So far, the researches on blast lung injury mainly involve damage model, pathogenesis, pathological changes, intervention treatment and so on, which has achieved great research findings. In the review, the authors summarize the progress of molecular mechanism for blast lung injury from the perspective of inflammatory reaction, oxidative stress, apoptosis and so on, which may promote the discovery of new targets for the diagnosis, treatment and rehabilitation intervention of blast lung injury.