Objective To investigate the effect of Scutellaria baicalensis stem-leaf total flavonoids(SSTF)on lipid metabolism in hyperlipidemia rats.Methods On the basis of establishing hyperlipidemia rat model,blood and liver lipids,lipid metabolic enzyme,and the amount of fecal bile acids were investigated after feeding of fatty emulsion for 30 days.Results Compared to the model group,SSTF significantly reduced the serum levels of total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),and increased high density lipoprotein cholesterol(HDL-C),increased the activity of lecithin cholesterol acyltransferase(LCAT).SSTF also showed the effect on decreasing liver TC,TG and increasing the amount of fecal bile acids.Conclusion SSTF have an effect on decreasing lipid metabolism in hyperlipidemia rats,and the possible mechanism is associated to the increase of LCAT activity and fecal bile acids excretion.

[Abstrcat] Objective To study the effects of acute alcoholism on blood gas analysis in rabbits. Methods Forty New Zelanian big-ear rabbits were divided into four groups randomly. The control group (Group A), the hemorrhagic shock group (Group B), the acute alcoholism group (Group C)and the acute alcoholism and hemorrhagic shock combination group (Group D). Results The volume of blood of Group D was less than Group B. The volume of lipid of Group D needed more. pH and PaO2 of Group D and Group B were decreased than Group A, PaCO2 and lactic acid were risen in the shock and recovered. pH and PaO2 of D Group were decreased than B Group, PaCO2 and lactic acid of D Group were risen than Group B. pH, PaO2, PaCO2 and lactic acid for different time and different group weren’t statistically significant. There was no interaction of pH, PaO2, PaCO2 and lactic acid in different time and different group. Conclusion It will achieved acidosis and decrease in partial pressure of oxygen after hemorrhagic shock. Acute alcoholism can aggravate them.

Objective:To investigate the correlation between serum calcitonin gene-related peptide (CGRP) and the culture outcome of in vitro fertilization embryo in male patients with infertility.Methods:In this study, the randomized samples from 25 male patients who received in vitro fertilization-embryo transfer (IVF-ET) in the 1st Affiliated Hospital of Fujian Medical University from June 2019 to October 2019 were analyzed by multiple linear stepwise regression, with some important clinical outcomes, such as the logarithmic conversion index of serum CGRP, fertilization method, masturbation difficulty, age, infertility duration, and prolactin, as independent variables, while total fertilization rate, normal fertilization rate, high quality embryo rate at day 3, blastocyst formation rate as dependent variables.Results:The Pearson correlation analysis showed that the D3 high-quality embryo rate was related to the normal sperm morphology rate in the primary infertility group ( r=0.537, P=0.048), the blastocyst formation rate was correlated with sperm density ( r=0.760, P=0.002), the CGRP logarithm was correlated with the total fertilization rate ( r=0.693, P=0.006). The logarithmic conversion index of serum CGRP was related to the total fertilization rate and normal fertilization rate in the secondary infertility group ( r=0.614, P=0.042 and r=0.611, P=0.046). In the secondary infertility group, there was a linear relationship between normal fertilization rate and total sperm count, serum CGRP log conversion, and sperm normal morphology rate, with standardized regression coefficients of 0.2, -0.729, and 6.8, respectively. Conclusion:Serum CGRP level, together with total sperm count and normal sperm morphology rate may affects normal fertilization rate in male patients with infertility.