Objective: To observe the effect of ATENS on distance and near vision and stereopsis in amblyopic children patients.Methods: 80 eyes from 70 patients with amblyopia were randomly divided into two groups: the group of ATENS and the group of western medicine.The difference of distance,near vision and stereopsis before and after treatment and between two groups after treatment were observed.Results: Distance and near vision improved and stereopsis diminished significantly after treatment in the TENS group and the western medicine group(P0.05).The curative effect and improving stereopsis in the western medicine group were better than that in the TENS group(P

Medical Picture Archiving & Communication System (PACS) and Radiology Information System (RIS) are the two embranchments of medical informatics developing most rapidly. The correlative legal issues of medical PACS and RIS should be paid attention to.

Objective To study the variations of the contents of trace elements in first section of tap water stagnating in pipe over night. Methods The first and middle sections of tap water stagnating in galvanized iron pipe for water supply over night for about 10 hours flowing through an iron tap and a chromed tap were sampled and determined for the contents of copper, manganese, iron and zinc by atomic spectrophotometry. The relationship between the variations of contents of four elements and the flow capacity was analyzed also. Results The contents of copper and manganese in the first section and middle section of tap water stagnating in pipe over night accorded with the sanitary standard for drinking water (SSDW), and revealed no significant differences between the first and middle section of tap water. The contents of iron in first section of tap water flowing through an iron tap and the contents of zinc in first section of tap water flowing through a chromed tap both exceeded the SSDW and revealed higher levels respectively compared with those in the related middle section of tap water. The levels of iron and zinc negatively correlated with the flow capacity (r Zn=-0.938,P

0.05) respectively. Conclusion: The SY 1 silicon elastomer have suitable physical, mechanical and anti ozone aging properties.

The effect of Ultraviolet (UV) rays on the activity of parasporal crystal of Bacillus thuringiensis, var. Kurstaki HD-1 strain was studied by SEM, SDS-PAGE, bioassay and other methods. It was found that the morphology and surface structure of PC were damaged ,and its solubility in alkaline solution or silkworm gut juice was decreased after being irradiated by UV, the solubility was lost completely after a long time irradiation over 5 hours, so the processed PC could not be degraded into protoxin with insecticidal activity and was denatured.

Objective:To study the effects of ozone aging on the color stability of the SY-1 silicone elastomer. Methods :40 SY-1 silicone elastomer samples were prepared and grouped into 4 with 10 in each group. The samples in each group were painted with gouache color, oil pigment and inorganic salt respectively, one group was used as the control. Then the samples were treated with ?=10 -4 % ozone at 10～16 mm/s for 72 h. The color of the samples were measured by 1976 CIE L *a *b * standards of chromatic aberration before and after ozone treatment. The chromatic aberration was expressed as △E=〔△L *)2+(△a *)2+(△b *)2〕 1/2. Results :After 72 hours of ozone aging, △E of the samples in the groups of control, gouache color, oil pigment and inorganic salt was 0.55?0.11, 3.55 ? 0.09, 1.40 ? 0.11 and 1.57 ? 0.07 respectively ;Conclusion:Under the ozone aging condition, the SY-1 silicone elastomers stained with oil pigment and inorganic salt may have better color stability than that with gouache color.

Neuropathy pain, or neuropathic pain (NP), which pathogenesis is complex and is lack of effective treatment, is one of common chronic pain in clinic. Studies of traditional Chinese medicine (TCM) in treating NP were increased in recent years. In the review, studies of treatments of TCM compound and monomer in NP during last decade were collected and analyzed to find out possible mechanisms, and some existing problems.

ObjectiveTo explore the relationship between plasma homocysteine (Hcy), polymorphism in 5,10-methylenetetrahydrofolate reductase (MTHFR) and cystathionine-β-synthase (CBS), and cerebral thrombosis.Methods87 subjects with first-ever acute cerebral thrombosis and 80 controls were studied. The plasma Hcy levels were measured using high-performance liquid chromatography-fluorescence detection (HPLC-FD). The polymorphism in MTHFR was determined by a polymerase chain reaction (PCR) assay and subsequent restriction enzyme digestion and that in CBS was determined by amplification refractory mutation system (ARMS).ResultsThe fast plasma Hcy level in the patient group was (15.28±4.33)μmol/L significantly higher than that ( 11.32 ±3.86)μmol/L in the control group (P<0.001). Different genotype had different influence on the plasma Hcy levels. There were no differences in genotype frequencies or allele frequencies between the patient group and control group (P>0.05).ConclusionCommon mutations in MTHFR, CBS G919A and CBS T833C lead to hyperhomocysteinemia. Hyperhomocysteinemia, but not common mutations in MTHFR and CBS is associated with the increased incidence of cerebral thrombosis.

OBJECTIVETo study the effect of aqueous extract of Taxus chinensis var. mairei (AETC) combined Erlotnib on the growth of A549 xenograft in nude mice and its mechanism.

METHODSThe xenograft model in nude mice was established by inoculating A549 cells subcutaneously. BALB/c nude mice bearing A549 xenograft were randomly divided into six groups, i.e., the low dose Erlotinib group (A) , the standard dose Erlotnib group (B) , the low dose Erlotinib combined AETC group (C), the standard dose Erlotnib combined AETC group (D), the AETC group (E), the control group (F), 12 in each group. Different medication was performed for 7 successive weeks after 24 h. One mL blood was withdrawn and tumor tissues taken. The tumor inhibition rate was calculated. The combined effect was analyzed by Jin's Formula [Q = Ea + b/(Ea + Eb-Ea x Eb) ]. mRNA and protein expression levels of epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), and B cell lymphoma-2 (Bcl-2) in xenografts were detected using real-time RT-PCR and ELISA.

RESULTSCompared with Group F, the xenograft weight was obviously lowered in Group B-E (P < 0.05, P < 0.01). The q value was 0.92 in Group C and 0.96 in Group D, which was obtained by simple adding of the two drugs. Compared with Group F, EG- FR mRNA expression in Group D and E, COX-2 mRNA expression in Group A-E; Bcl-2 mRNA expression in Group B-D; COX-2 protein expression in Group B-E; Bcl-2 protein expression in Group C and D were obviously lowered with statistical difference (P < 0.05, P < 0.01).

CONCLUSIONSAETC combined low dose and standard dose Erlotinib had synergistic effect on tumor inhibition. Its mechanism might be associated with down-regulating mRNA and protein expression levels of COX-2 and Bcl-2.

Animals ; Antineoplastic Agents ; pharmacology ; Antineoplastic Combined Chemotherapy Protocols ; pharmacology ; Cell Line, Tumor ; Cyclooxygenase 2 ; metabolism ; Drugs, Chinese Herbal ; pharmacology ; Enzyme Inhibitors ; pharmacology ; Erlotinib Hydrochloride ; pharmacology ; Heterografts ; Lung Neoplasms ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Receptor, Epidermal Growth Factor ; metabolism ; Taxus ; Transplantation, Heterologous

Objective To explore the influence of continued case nursing on medicine compliance and disease relapse of patients with schizophrenia.Methods Eighty patients with schizophrenia were divided into experiment group and control group according to admission sequence and random digit table,with 40 in each group. Both groups received case management. The control group received routine outpatient visit.The experiment group received continued nursing of primary nurse’s case management based on traditional method for a year.The two groups were compared in terms of the medicine compliance and disease relapse.Result The medicine compliance of the experiment group was higher than that of control group and the disease relapse of the experiment group was lower than that of control group(P<0.05).Conclusion The continued case nursing to patients with schizophrenia can increase medical compliance and reduce incidence of disease relapse,which is an effective hospital-community management mode.