The long-year program for medical education is the major way to train the high level medical professionals.This paper colleeted the research papers on this topic published in Chinese journals in recent years,extracted their key words and counted the high frequent key words According to the co-occurrence of a pair of key words in one paper.these high frequent keywords were clustered into groups.The research structure and main directions of the long-year program were outlined as the study of macro-planning of long-year program,the study of teaching models and teaching system,study of teaching practice.These results could be a useful reference for the medical educational researchers and managers.

Objective To analyze multislice CT characteristics of intestinal obstruction transition zone caused by different patholo-gy.Methods 67 cases of intestinal obstruction were collected in our hospital.Multislice spiral CT scan combined with multi-plane re-organization (MPR)of the bowl obstruction transitional zone were analysed.Results Among 67 cases of intestinal obstruction,there were 28 cases of simple mechanical intestinal obstruction,1 7 cases adhesion intestinal obstruction,5 cases paralytic intestinal obstruc-tion,4 cases internal hernias and 4 cases mixed intestinal obstruction.Conclusion Intestinal canal transitional zone and arounding tis-sues of intestinal obstruction have certain characteristics for the same pathology which can be clearly displayed by multislice CT scan combined with MPR.

Objective To find a new method of tangential view of patello femoral joint. Methods 62 cases of lateral knee radiographs were studied. The knee flexion angles, patello femoral angles, patello tibial angles and frontal patello tibial angles were measured and their relationships analyzed. The knee flexion angles and the patello femoral angles had linear relationship with a linear equation = 2 + 0.8x . The angles of posterior patellar line with tibial long axis and frontal tibial line were 3.3? and 12.7?respectively. According to the measurement results, an accessary positoning table was designed. The patients′ patello femoral joints were examined with the knee flexed at an angle of 30?. The patients were in supine position and the central X ray was angled at 73?vertically toward the film. Results 58 patello femoral joints of 40 patients were radiographically studied (10 males, 30 females) .All radiographs were classified into 4 degrees as Grade A, B, C and D. Eighteen cases were Grade A (31%), 30 cases were Grade B(52%), 8 cases were Grade C(18%)and 2 Grade D(3%).The reason for Grade D was due to small or negtive anterior patellotibial angles. Conclusion This new method of tangential view of patello femoral joint is accurate, comfortable and simple and could be used as routine examination for patello femoral joint diseases.

Objective:To compare the visual quality of patients with astigmatic multifocus intraocular lens (ART IOL) and astigmatic monofocus IOL (Toric IOL) after implantation.Methods:A prospective, non-randomized, controlled study was conducted to include 72 eyes of 72 cataract patients with corneal astigmatism (1.0-2.5 D) who were scheduled to receive phacoemulsification combined with IOL implantation in Chaoju Eye Hospital of Inner Mongolia from July 2017 to October 2018.Patients were divided into ART IOL group (37 eyes) and Toric IOL group (35 eyes) according to different IOLs implanted.All patients were followed up for 1 year after surgery.The main and secondary outcome indicators were compared.The main outcome indicators included distance (5 m), intermediate (80 cm), and near (40 cm) uncorrected visual acuity and best corrected visual acuity, defocus curve, contrast sensitivity, postoperative IOL rotation and residual astigmatism, while the secondary outcome indicators included visual subjective symptoms and spectacle independence rate.The above outcome indicators were compared between the two groups.This study followed the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of Chaoju Eye Hospital of Inner Mongolia (No.CJYKLL202012).Written informed consent was obtained from each patient before surgery.Results:There was no statistically significant difference between the two groups in average uncorrected distance visual acuity and best corrected distance, intermediate and near visual acuity (all at P>0.05).The average intermediate and near visual acuity in the ART IOL group was significantly higher than that in the Toric IOL group, showing statistically significant differences (both at P<0.05).The defocus curve of the ART IOL group presented a double peak, which reached the peak at the far focus (0.0 D) and near focus (-2.5 D), respectively.The visual acuity range from 1.5 to-3.0 D was above 0.2 logarithm of the minimum angle of resolution (LogMAR), and the focus depth range was 4.5 D (1.5 to -3.0 D).The defocus curve of the Toric IOL group had only one crest, which was located at best corrected visual acuity (0.0 D).The visual acuity reached 0.2 LogMAR or above were from 1.0 to -1.0 D, and the focal depth range was 2.0 D (1.0 to -1.0 D).There was no statistically significant difference in contrast sensitivity at different spatial frequencies between the two groups in bright light, bright flashing light and dark light (all at P>0.05), while the contrast sensitivity of the ART IOL group at high dark flashing light frequency was lower than that of the Toric IOL group, showing statistically significant difference ( P<0.05).In the ART IOL group and the Toric IOL group, the average residual astigmatism after surgery was (-0.47±0.51)D and (-0.49±0.42)D, respectively, with no statistically significant difference ( t=0.408, P>0.05).There was no significant difference in postoperative IOL rotation between the two groups ( t=1.906, P>0.05).The total postoperative spectacle independence rate in the ART IOL group was 97.30%(36/37), which was higher than that in the Toric IOL group (17.14%, 6/35), showing statistically significant difference ( χ2=15.320, P<0.05). Conclusions:Both Toric IOL and ART IOL can better correct corneal astigmatism and improve patients' distance visual acuity, but ART IOL implantation can provide better distance, intermediate and near visual acuity, and higher spectacle independence rate.

Objective To explore the effects of focused settlement mode applied in caring the acute paraquat poisoning patients.Methods 106 hospitalized patients with acute paraquat poisoning were randomly divided into the control group and the experimental group.All patients in the control group were performed conventional nursing instruction and the experimental group was nursed with focused settlement mode on the basis of conventional nursing instruction.The efficacy of nursing was evaluated when they were discharged from hospital.Results The self-care skills and knowledge,consciously following the medical behavior,satisfaction degree with clinical service of the experimental group were significandy better than the control group,while the hospitalization days were shorter than the control group.Conclusions Focused settlement mode can improve the effect of nursing care for patients with acute paraquat poisoning.

Objective:It is verified whether JJF1308-2011 standard is scientific and reasonable, whether it is easy to operate and achieve the technical requirements of the testing medical sterilizer temperature by analyzing and evaluation the uncertainty of experimental. Methods:The temperature detection device is used to obtain experimental data in the condition of no-load. The result is concluded after analysis and evaluation of uncertainty. Results:The specification is verified to reach the feasibility and rationality through the no-load test and analysis and evaluation of uncertainty of the results. Conclusion:It is proved that the specification is easy to operate through the experiment. It can meet the requirement of testing the quality and safety of sterilizer.

Wnt signaling pathway is one of canonical pathways that can regulate diverse processes such as cell proliferation,differentiation,migration.Interaction between Wnt ligands and Wnt receptors results in an activation ofdifferent intracellular signaling pathways,and Wnt/β-catenin signaling pathway has been proved to have a close relationship with pancreatic cancer.This review presents a brief overview of Wnt/β-catenin signaling pathway in the mechanism of the tumorigenesis of the pancreatic cancer at deregulation of cell cycle,apoptosis,cancer stem cells and angiogenesis.

Objective:To develop a compound erythromycin nose drops,according to the pathology of rhinitis and characteristics of medicines.　Methods:This compound consists of two components:a solid component (capsule containing pulvis of erythromycin lactobionat) and a liquid component (the water solution of diphenhydramine hydrochloride and ephedrine hydrochloride). When using,you have only to put the collocystis to the liquid and sway to achieve thixotropy.　Results:This compound medicine mainly apply to acute and chronic as well as allergic rhinitis. A clinical observation of 180 cases showed an effective rate of 91.11% and a cure rate of 68.33% using this compound we developed. When observing another group of patients (totally 169 cases),an effective rate of 57.99% and a cure rate of 30.77% were achieved by using chloramphenicol and ephedrine nasal drops. The difference between this two medicines is notable.　Conclusion:The technique for preparing this compound medicine is simple and easy,the raw materials easy to get,and the price cheap. This preparation is effective in the treatment of rhinitis and worth popularizing.

Breast milk is the normative standard for infant nutrition and contains a wide variety of proteins that contribute to its unique qualities.Bile salt-stimulated lipase and amylase assist in the digestion and utilization of micronutrients and macronutrients from the milk.Several proteins with antimicrobial activity,such as immunoglobulins,lactoferrin,k-casein,lysozyme and lactoperoxidase,are relatively resistant against proteolysis in the gastrointestinal tract and may,in intact or partially digested form,contribute to the defense of breastfed infants against pathogenic bacteria and viruses.Cytokines,colony stimulating factor and chemokine have immunomodulatory activities,whereas insulin-like growth factor,epidermal growth factor and peptides from caseins are likely to be involved in the development of the intestinal mucosa and other organs of newborns.In combination,breast-milk proteins assist in providing adequate nutrition to breastfed infants while simultaneously aiding in the defense against infection and facilitating optimal development of important physiologic functions in newborns.

Objective To observe the effect of Juanbi granulae on rheumatoid arthritis belonging to cold dampness obstruction and kidney yang qi deficiency syndrome.Methods All 120 RA patients in accordance with the inclusion criteria were divided into a 80 cases of study group,and a 40 cases of control group,by random table method.Methotrexate,10mg once a week,was given orally,as a basis for treatment.The treatment group given Juanbi granulae,15g for each time,3 times a day; while the control group was Zhenqingfengtongning sustained-release tablets,60mg for each time,twice daily.Both groups have adopted a one-month course of treatment.Statistics effect was evaluated after 4-week course of treatment.Results ①There was significant difference between the two group in terms of therapeutic effects and symptom effects after the treatment (the total effective rate of study group and control group was 100.0％,86.7％,U value was-4.071,-3.232 respectively,P＜0.05).② The treatment effects and the symptom effect of the cold dampness syndrome and the kidney yang qi deficiency syndrome in the same group showed statistical difference after the treatment (the total effective rate of study group and control group was 88.0％,80.0％,The U value of treatment effect was-5.50,-3.67 respectively,P＜0.01 or P＜0.05).(U value of syndrome effect was-2.909,-3.992 respectively,P＜0.05).③ Study group of after treatment ESR (17.05±7.15) mm/h,RF (32.46± 14.22) U/L,compared with the control group of after treatment,the difference was statistically significant (P＜0.05).Conclusion Juanbi granulae was effective in treating rheumatoid arthritis of both kidney yang qi deficiency syndrome and cold dampness obstruction syndrome,the effects were especially better for cold dampness obstruction syndrome.