The effects of dauricine on tolerance to anoxia in mice and on experimental myocardial ischemia and infarct in rats were investigated .Dauricine was found to be capable of increasing the tolerance of mice to anoxia and prolonging life and decreasing oxygen consump-sion.Dauricine improved the ECG L-Ⅱ "J" point change induced by pituitrin and LAD ligation, and reduced the rate of the development of pathologic Q wave and the infarct size induced by LAD ligation as indicated by N-BT staining in rats. The results suggest that dauricine offered beneficial effect on the experimental ischemia and infarct. Dauricine; Propranolol; Verapamil; Nifedipine; Pituitrin; ECG; Myocardial infarct

Objective     To identify the risk factors for postoperative recurrence of peripheral solid small-nodule lung cancer (PSSNLC) (T≤2 cm), and to explore the effects of surgery types on prognosis. Methods     We extracted data from Western China Lung Cancer Database (WCLCD), a prospectively maintained database at the Department of Thoracic Surgery, West China Hospital, Sichuan University, and Surveillance, Epidemiology, and End Results (SEER)  database for peripheral solid small-nodule lung cancer patients (T≤2 cm N0M0, stageⅠ) who underwent surgery between 2005 and 2016. We used univariable and multivariable logistic regression to analyze risk factors for recurrence of PSSNLC. We applied propensity-score matching to compare the long-term results of segmentectomy and lobectomy, as well as the survival of patients from WCLCD and SEER. We finally included 4 800 patients with PSSNLC (T≤2 cm N0M0)(WCLCD: SEER=354∶4 446). We matched 103 segmentectomies and 350 lobectomies in T≤1 cm, and 280 segmentectomies and 1 067 lobectomies in 1 cm