Objective To observe the clinical curative effect of the FUFANGDANSHENDIWAN on the acute myocardial infarction patients. Methods 75 acute myocardial infarction patients were randomly divided into two groups,the curative group( A group) 45patients, and the control group( B group)30 patients, patients inTwo groups were treated wigh thrombolytic intravenous drip urokinas, A groupe patients oral admnistered the FUFANGDANSH-ENDIWAN,B group patients oral administered aspirin,the course ti treatmant is two weeks. The change tithe level of blood theology, the record points of QRS wave of the electrocardiogram, and the square of myocardial infarction were observed. Results The change of the level of blood rheology, the record points of QRS wave of the electrocardiogram (4.45±0.82),and the square of myocardial infarction(25.20±3.40),of A group compared with B group,the difference is significant. ( P<0.05 orP<0.01 ). Conclusion The FUFANGDANSHENDIWAN had effect on the a-cute myocardial infarction.

From October 1997 to December 1998, 64 patients with defect of skull vault bone were divided into 2 groups. The 1st group of 33 patients underwent an orthopedic surgery to recreate the defect using their self exploited bone and the 2nd using the carbone composite flap. The technique of use of carbone composite was not complicated and can be applied in any surgical institution which had used to conduct emergency surgery of skull and brain. The priorities in indication must be given to large and very large defect.
Surgery, Plastic ; Therapeutics ; Bone and Bones ; Skull ; Orthopedics

From Oct. 1997 to Oct. 1999 in Neurosurgery Department of St Paul Hospital, Ha Noi, 42 patients ≥ 4 years old underwent a cranioplasty for skull lacuna using carbon composite "intost-2". The pathologic postoperative conditions were 14.29% with extradural hematomas, 30.95% subdural hematomas, 54.76% cerebral wounds; located on frontal sited 40.48%, temporal 33.33%, parietal 21.43%, occipital 4.76%. Surgical produres were scar removal and cranioplasty 78.58%, scar removal and meningoplasty and skull repair 21.43%. These 42 cases were carried out succesfully with 7-10 hospital days, symptoms caused by skull lacuna were improved, only 1 case of failure
Skull ; Pain, Postoperative ; carbon

Assessment the efficacy of cranioplasty with frozen self-cranial bone on 47 patients at the Department of neurosurgery, Saint Paul hospital between May 2002 and March 2005. The patients consisted of 37 males and 10 females, the mean age was 28 (16 to 63 years old). In all patients, cranioplasty had been performed to repair bone defects secondary to severe brain injury. 38/47 patients (80.85%) had fronto-temporal defect while 27 patients had very large defect (> 80 cm2). Results: the operation successful rate was 90.24% (37/41 patients) and no complications. 4 cases need secondary cranioplasty while 2 patients were done with carbon composite.
Bone and Bones ; Skull

Based on the connotation of ISO15189 and philosophy of current laboratory medicine,this article discussed about the important significance and role of quality management in diagnosing and curing of patients during post-analytic phase.This article also expounded the attention to these questions of examination results verification,procedure of reviewing and reporting examination results,establishment of principle for reserving samples after examination,range of consulting service and methods of handling complaint,the relationship between the whole quality management and information exchange of laboratory and clinical department.

In order to implement the spirit of the document awarded by the three ministries,promote the medical reform process of public hospital,promote the heahhy development of the laboratory medicine,this paper expounds the significance of the study and implementation of the file,and puts forward several ideas.

Objective To explore which scoring methods can prevent the ischemic stroke better.Methods 80 padents with atrial fibrillation were randomly divided into two groups,the patients in A group took anticoagulant therapy using CHADS2 score;the patients in B group took anticoagulant therapy using CHADS2-VAS score;follow-up the ischemic stnoke,death and major bleeding event rate.Results 7 cases of ischemic stroke in A group,1 case in B group,the difference was statistically significant ( P ＜ 0.05 ).Conclusion According to CHA2DS2-VAS score for risk stratification,anticoagulant therapy was safe and effective,and did not increase bleeding event rate.

According to The National Comprehensive Cancer Network or St. Gallen criteria, many node-negative breast cancer patients are advised to receive chemotherapy, however, research has not demon-stinted that chemotherapy benefits all of them equally. Multigene assays, based on analysis about the genetic in-formation of tumors, are likely to provide doctors with a better understanding of the aggressiveness of individual tumors, and a better assessment of a patient's likely benefit from chemotherapy. Great progress has been made on the research of 21, 76, 70, 28 multigene assays. Among them, 21 gene assay is the most prospective,which has been recommended by The National Comprehensive Cancer Network in 2008 to use in the systemic adjuvant treatment decision in certain indications.

Traced back to the one decade's development of research ethics in China,the author summarizes the current issues,such as: not sufficient implementing of informed consent,relatively loose review of IRB,IRBs lack ability to improve the review level and not provide much education opportunities to researchers,and not yet take account into the continuous review to the protocols approved before.By comparing the current issues of China and the conditions of U.S.in 1998,we can find some similarities exist,so we can learn from the lessons and experiences of the development of research ethics in the United and the other country,such as adding the model of region ethical review committee,instead of only institutional IRB.The author aims to point out some general ideas about research ethics capacity building,enforce training continuously,government pay much attention to IRB regulation and consider much on cultural elements,which are all bases for the road of sustainable development of research ethics in China.

Seven cellular parameters in adenomatous hyperplasia of the liver (AHL), compared with normal liver cells (NLC) and hepatocellular carcinoma (HCC), were analyzed quantitatively by measuring the seven parameters of the cell nuclei, the area (AREA), perimeter (PERIM), maximum diameter (DMAX), minimum diameter (DMIN), the equivalent circle diameter (DCIRCLE), circularity shape factor (FCIRCLE) and shape factor (FSHAPE) using computerized image analyzer. The main results were: (1) All the above seven nuclear parameters in AHL were significantly different from those in NLC, three parameters (DMAX, DMIN and FSHAPE) in AHL were not obviously different from those in HCC, indicating that AHL and NLC were not of the same cellular population, and AHL had a tendency of approaching HCC in the nuclear features; (2) Not alike NLC and HCC, the scattered distribution between nuclear FCIRCLE and DCIRCLE in AHL presented a highly dispersed distribution, overlapping the areas of NLC and the greater part of HCC, suggesting that AHL being an abnormal cellular population composed of cells in different proliferative status between NLC and HCC; (3) All of five resected AHL in the present study showed early malignant transformation. We conclude that AHL possesses the general features of precancerous lesion, and should be considered as the important precancerous lesion of HCC.