Background: Atrial Septal Defect (ASD) is a common congenital cardiac disease, accounting for 10% of congenital heart diseases and 1/3 congenital heart defect in adults. Closure of ASD is often used as a treatment method. However, there is controversial opinions about ASD closure in adult >=40. Objective: To study the outcomes of ASD closure of in adults >= 40 years. Subject and Method: 40 patients (27 female and 13 male) of ASD ostium secundum with an age average of 48.85 +/-5.91 (40 \u2013 62 years) and the mean ASD sizeof 27.53 +/-8.37 mm, mean Qp/Qs of 2.97 +/-1.59 had indications for ASD closure (clinically symptomatic and/or right ventricular [RV] enlargement by echocardiography). Follow-up at 1 week, 1 month, 3 months, 6 months after ASD closure. Results: Left ventricular systolic function was unaffected by ASD closure and the majority of the patients reported improvement in their symptoms. The right ventricle end-diastolic dimension and pulmonary artery diameter decreased significantly (p<0,0001). No trivial shunts. Conclusion: ASD closure is safe and effective in patient over 40 years of age with minimal complications. The procedure resulted in a decrease in the RV size that was accompanied by improvement in clinical symptoms.
Atrial septal defect ; Closure of ASD