Objective To explore relationship between functional dyspepsia(FD)and psychological factors,and study the efficacy of prokinetics and antianxiety drugs,antidepressants.Methods Totally 220 FD patients were assessed with SAS,SDS,then compared the scales with norm,and 132 FD patients with abnormal SAS or/and SDS scores were randomly divided into mosapride,paroxetine,and mosapride plus paroxetine groups,each group have 44 cases and were treated for 8 weeks.Mosapride group were given mosapride 5mg,tid,po;Paroxetine were given 10mg,qm,po.Mosapride plus paroxetine group were given mosapride 5mg,tid,po plus paroxetine10mg,qm,po. Results The average scores of every scale were significantly higher than that of norms(P