Background: Most abdominal surgery can be done by laparoscopic method. For urologic surgery, laparoscopic surgery is used to cut the kidney, prostate, seminal vesicles and get urinary stones, including the ureter stones.\r\n', u'Objectives: Contribute to improving treatment effects ureter stones by lapasoscopy tranperitoneal ureterolithotomy\r\n', u'Subjects and method: Laparoscopic transperitoneal ureterolithotomy was attempted in 90 patients (50 men and 34 women) with an age range of 22 \ufffd?75 years (mean 43.60+ 11.97 years). Learn characteristics of ureteral calculi (X-ray, ultrasound, urinary map vein) and surgical methods.\r\n', u'Results:The results showed that: Most ureterolith at L3 vertebral level (55.6%) and L4 (40.0%). The stone size ranged from 8 to 22mm (mean 13.87+ 3.25mm) and an average width 4 to 12mm (mean 6.96 + 1.82mm). Most cases of ureteral calculi with the situation fluid in the kidney level 2 (76.7%). The stone has impacted in the upper and mid ureter. Two 10-mm and one 5mm trocars were used. Most cases of stage 2 nasal. The mean operative time was 57.22 + 15.51 minutes (30-90 minutes). \r\n', u'Conclusion: The authors conclude that laparoscopic ureterolithotomy by the transperitoneal approach is a safe and reliable minimally invasive procedure. For large, hard, long-standing and impacted ureteric calculi, one laparoscopicureterolithotomy is an initial therapy\r\n', u'
Ureterostomy ; Laparoscopy

Background: Plasma lipids are affected not only by dietary intake and life style but also by genetic factor. Objective: To discover the relationship between plasma lipids and the presence of LPL S447X and PAF-AH V279F in the bodies of rural Vietnamese population. Subject and Method: One hundred and ninety three subjects were randomly selected from rural areas in Ho Chi Minh city. The presence of LPL S447X and PAF-AHV279F polymorphism was determined using an Invader assay, and the plasma lipid levels were measured by an enzymatic method. A profile regarding the dietary intake was also made for each subject. Result and Conclusion: The frequency of LPL 447SX/XX (12.2%) polymorphism, PAF-AH Val279Phe mutation allele frequency (5.4%) in the Vietnamese was closely similar to that of other Asian populations. LPL447X polymorphism was found to be significantly associated with a higher HDL-C level in comparison to LPL 447S. LPL S447X affects plasma HDL-C and TG concentration in Vietnamese rural population.
Genetic factors ; plasma lipids ; rural area

The low-density lipoprotein cholesterol (LDL-C) is established as a causative agent of atherosclerotic cardiovascular disease (ASCVD) and lowering plasma LDL-C levels represents the main approach to reduce the risk of cardiovascular events. Statins remain the cornerstone of drug therapy for dyslipidemia. Although moderate- to high- intensity statin therapy has demonstrated consistent benefits for secondary prevention of cardiovascular events, statin monotherapy is insufficient to achieve the guideline-recommended LDL-C levels for high- and very high-risk patients. Some patients cannot tolerate statins, especially when taking long-term high doses. Several non-statin drugs that have a complementary mechanism of action to statins are now available, including ezetimibe, monoclonal antibodies targeted to proprotein convertase subtilisin/kexin type 9 (PCSK9 mAb), and, more recently, inclisiran, bempedoic acid, and evinacumab. Considering the recommendations from guidelines by domestic and international cardiovascular associations, combining these drugs should be contemplated to attain treatment goals for patients.