[Objective] To observe the clinical efficacy of treatment on Frequent Postoperative Posner-Schlossmann syndrome in cataract intraocular lens using Chinese medicine with the effect of tonifying the liver and kidney, nourishing yin and suppressing hyperactive yang.[Methods] 46 cases of Posner-Schlossmann syndrome were randomly divided into two groups, one was the Chinese Medicine group ,in which al cases were treated with Chinese herbs and local eyedrop at the time of first onset after operation; another was the control group, in which al cases were treated with local eyedrop. [Results] Within two years after treatment, compared with the control, in the Chinese Medicine group, the cases of recurrence of Posner-Schlossmann syndrome were obviously decreased. [Conclusion] Chinese medicine with the effect of tonifying the liver and kidney, nourishing yin and suppressing hyperactive yang shows definite effect on postoperative Posner-Schlossmann syndrome, it can decrease the occurrence frequency of number.

[Objective] To evaluate the effect of Ginkgo biloba extract on optic nerve in progressive normal-tension glaucoma patients. [Methods] 60 cases of patients suffered from controlled normal-tension glaucoma were randomly divided into control and treatment groups, 30 cases in each respectively. The patients in the control group received the conventional treatment(eye drops or surgical treatment), additionally the patients in the treatment group received Ginkgo biloba extract(twice a day ,1ml each time). 5 months was a therapeutic course, after 3 therapeutic courses the best corrected visual acuity, ocular hemodynamics, visual field, retinal nerve fiber layer thickness and optic disc data were detected and statistically studied. [Results] There was no significant difference in the best corrected visual acuity between control group and treatment group( P>0.05). The end diastolic velocity(EDV), peak systolic velocity(PSV) were increased significantly and resistive index(RI) was decreased significantly in treatment group after treatment( P<0.05), while the EDV, PSA, RI in control group before and after treatment were without significant differences( P>0.05). The mean visual field defects(MD) in treatment group after treatment were much lower than the control group( P<0.05). The reduction trends of the retinal nerve fiber layer thickness and rim area in treatment group after treatment were slower than control group significantly decreased( P<0.05). [Conclusion] Ginkgo biloba extract can improve the ocular hemodynamics, delay the deterioration of the best corrected visual acuity and visual field damage, extend the losing time of visual retinal nerve fiber layer thickness and rim area. It has protective effect on optic nerve in normal-tension glaucoma.

Objective To explore the effect of specialized care of iodophor uterine cavity wipe on prevention of incision infection in acute cesarean section pregnant women.Methods A total of 50 patients with acute cesarean section were enrolled in this study,and were randomly divided into two groups.The patients in the control group were given routine nursing,while the patients in the experimental group were treated with special care and iodophor cavity wipe,cesarean section related parameters,the relevant clinical indicators,clinical events,subjective feelings and family care satisfaction were compared.Results The scores of SAS and SDS,systolic blood pressure,diastolic blood pressure,heart rate,total white blood cell count,postoperative pain score,time to first bed-off,time to first exhaust,time to first breast milk,feeding times of alternative milk,postoperative 24 h body temperature and the rate of incision infection in the observation group were lower than that of the control group (P ＜ 0.05).The scores of breastfeeding and subjective feeling were higher in the experimental group than in the control group (P ＜ 0.05).The satisfaction degree of the family members was better than that of the control group (P ＜ 0.05).Conclusion The application effect of special care and iodophor uterine cavity wiping in the treatment of acute cesarean section pregnant women are obvious,and it can improve nursing satisfaction,so it is of great significance in promotion.

Objective To explore the effect of specialized care of iodophor uterine cavity wipe on prevention of incision infection in acute cesarean section pregnant women.Methods A total of 50 patients with acute cesarean section were enrolled in this study,and were randomly divided into two groups.The patients in the control group were given routine nursing,while the patients in the experimental group were treated with special care and iodophor cavity wipe,cesarean section related parameters,the relevant clinical indicators,clinical events,subjective feelings and family care satisfaction were compared.Results The scores of SAS and SDS,systolic blood pressure,diastolic blood pressure,heart rate,total white blood cell count,postoperative pain score,time to first bed-off,time to first exhaust,time to first breast milk,feeding times of alternative milk,postoperative 24 h body temperature and the rate of incision infection in the observation group were lower than that of the control group (P ＜ 0.05).The scores of breastfeeding and subjective feeling were higher in the experimental group than in the control group (P ＜ 0.05).The satisfaction degree of the family members was better than that of the control group (P ＜ 0.05).Conclusion The application effect of special care and iodophor uterine cavity wiping in the treatment of acute cesarean section pregnant women are obvious,and it can improve nursing satisfaction,so it is of great significance in promotion.

Objective To analyze whether occur pain during radiofrequency ablation ( RFA ) by preoperative monitoring of vital signs and recording the types and amount of radiofrequency ( RF) needles, so as to enhance predictive nursing ability and effects of pain management. Methods We retrospectively analyzed the relationship between preoperative vital signs, types and amount of RF needles with intraoperative pain among 367 primary liver cancer patients from February to October 2013. The Logistic regression model was used for statistical analysis. Results The pain influencing factors included preoperative systolic pressure, preoperative heart rate, ablation area and amount of RF needles (β= -0. 208 0, 0. 105 5, 0. 210 9, 0. 179 3;P<0. 05). Conclusions Nurses can predict the status of intraoperative pain according to monitor vital signs, also can predict the rate of pain by the types and amount of RF needles, so as to provide evidence for he prediction nursing of RFA.

Objective:To explore the influences of WeChat platform combined with problem-based learning (PBL) teaching method on the theoretical examination results, practical skills scores and satisfaction of nursing students in operating room.Methods:A total of 124 undergraduate nursing students from June 2018 to December 2019 from the operating room of The Affiliated Women's and Children's Hospital, School of Medicine, UESTC were selected as the control group, among which, 62 nursing students from June 2018 to March 2019 were selected as the control group, and 62 nursing students from April to December 2019 were selected as the research group. The control group adopted the traditional teaching method, and the research adopted WeChat platform combined with PBL teaching method. The results of theoretical examination, skill practice, preparation for autonomous learning, critical thinking ability and teaching satisfaction were compared between the two groups. SPSS 23.0 was used for t test. Results:The scores of theory examination and skill practice in the study group were higher than those in the control group ( P<0.05); after practice, the scores of self-management, love of learning and self-control in the study group were higher than those in the control group ( P<0.05); after practice, the scores of the three dimensions of curiosity, truth seeking, systematization ability and total score in the study group were all higher than those in the control group ( P<0.05); the satisfactions of the research group on teaching content, teaching problem design and teaching effect were higher than those of the control group ( P<0.05). Conclusion:The combination of WeChat platform and PBL teaching method can improve the knowledge mastery level of nursing students in operating room, cultivate their self-learning ability and critical thinking ability, and nursing students are more satisfied with the teaching mode.

Objective To explore the value of energy spectrum CT based material imaging for quantitatively and qualitatively evaluating lumbar intervertebral disc degeneration.Methods Lumbar energy spectrum CT and MRI were collected from 82 patients with back and leg pain,and 74 keV CT,water(chondroitin sulfate[CS])and CS(water)material images were obtained.Intervertebral discs Pfirrmann grading(PG)was performed based on MRI.CT values,water(CS)and CS(water)concentration of nucleus pulposus(NP)and annulus fibrosus(AF)in lumbar intervertebral disc with different PG grades were compared,and the relations with PG grades were analyzed.Visual classification of lumbar intervertebral disc was performed based on water(CS)and CS(water)falsecolor map,while PG distribution of different visual classification were compared,and the relations with PG grades were observed.Results Totally 250 lumbar intervertebral discs were enrolled,including 22 of PG Ⅰ,49 of PG Ⅱ,83 of PG Ⅲ and 96 of PG Ⅳ.CT values,water(CS)and CS(water)concentration of anterior AF,NP and posterior AF of intervertebral disc with different PG grades were significantly different(all P＜0.001),and CT values were negatively correlated with PG grades(rs=-0.504,-0.399,-0.258,all P＜0.001),while water(CS)concentration was positively correlated(rs=0.476,0.753,0.324,all P＜0.001)but CS(water)concentration was negatively correlated with PG grades(rs=-0.486,-0.760,-0.329,all P＜0.001).Significant differences of PG grades were found among different water(CS)and CS(water)falsecolor images visual classification(all P＜0.001),while water(CS)and CS(water)falsecolor images visual classification were all positively correlated with PG grades(all rs≥0.700,all P＜0.001).Conclusion Energy spectrum CT based material imaging could be used for quantitatively and qualitatively evaluating lumbar intervertebral disc degeneration.

Objective:To explore the urodynamic characteristics of bladder function in patients with abnormal urination after radical hysterectomy of cervical cancer.Methods:In a prospective self-controlled study, a total of 84 patients with cervical cancer and clinical stage of ⅠB to ⅡA, meeting the preoperative inclusion criteria in our hospital from January 2016 to June 2018 were enrolled.All patients were tested for urodynamic testing 1 week before and 6 months after surgery.Patient bladder function status was observed and evaluated before and after surgery and urodynamic examination results were analyzed.Results:Of 84 study cases, the 58 patients developed abnormal urination after radical surgery, there were no urination abnormalities in 26 cases.There was no significant difference in age, clinical stage and pathological diagnosis between patients with and without urination abnormalities.Abnormal urination after radical surgery included difficulty in urinating(55%), frequent urination with a feeling of urination not complete(34%), stress urinary incontinence(7%), and urinary incontinence(4%). Among the 26 patients without urination abnormalities after radical surgery, only one case showed an abnormal urodynamic examination(abnormal bladder sensation). In patients without abnormal urination after surgery, differences in the urodynamic examination findings between pre-and post-surgery were not statistically significant(all P> 0.05). At the same time, in all cases of abnormal urination after radical hysterectomy of cervical cancer, 43 patients(74%)with bladder dysfunction had normal urination pattern before operation, but after operation, the urination abnormality required abdominal pressure.Of the patients with bladder dysfunction after surgery, the maximum flow rate(Qmax)was(12.9±10.3)ml/s, the average flow rate(Qave)was(6.0±4.2)ml/s, the voided volume was(148.0±36.8)ml, voiding time was(32.9±22.1)s, maximum flow time was(11.4±5.0)s, postvoid residual urine was(260.2±219.2)ml, maximal detrusor pressure was(12.1±8.9)cmH 2O, bladder compliance was(16.1±4.3)ml/cmH 2O, normal desire to void was(354.5±204.3)ml, maximal capacity was(587.4±152.5)ml, maximum urethral pressure was(97.6±33.1)cmH 2O, maximum urethral closure pressure was(89.9±36.4)cmH 2O, and function urethral length was(29.6±6.5)mm; In comparison, the above indexes-corresponding values at 1 week before surgery were respectively as follows: the Qmax was(25.1±11.4)ml/s, the Qave was(11.4±6.6)ml/s, the voided volume was(318.6±96.4)ml, voiding time was(29.2±18.5)s, maximum flow time was(6.7±3.9)s, postvoid residual urine was(29.9±21.5)ml, maximal detrusor pressure was(31.9±21.4)cmH 2O, bladder compliance was(78.1±33.9)ml/cmH 2O, normal desire to void was(258.2±185.5)ml, maximal capacity was(335.1±124.9)ml, maximum urethral pressure was(96.4±33.9)cm H 2O, maximum urethral closure pressure was(88.5±35.2)cmH 2O, and function urethral length was(37.2±7.2)mm.It can be seen that Qmax, Qave, voided volume, maximum detrusor pressure, bladder compliance, and functional urethral length in patients with abnormal urination are significantly lower after radical hysterectomy of cervical cancer than before the surgery.While, normal desire to void, maximum capacity, maximum flow time, and postvoid residual urine volume were higher after radical hysterectomy than before surgery( P<0.05). In addition, there was no significant difference in voiding time, maximum urethral pressure and maximum urethral closure pressure between pre-and post-operation.Besides, it is worth noting that there was no significant difference in preoperative urodynamic test results between patients without abnormal urination versus patients with abnormal urination( P>0.05), and the difference in urodynamic test results between the two groups is statistically significant( P<0.05). There was no statistically significant difference in abnormal urination and in urodynamic test results between different clinical stages and between different pathological types( P>0.05). Conclusions:The characteristics of urinary dynamics in patients with abnormal urination after radical hysterectomy of cervical cancer are mainly manifested as decreased bladder sensory function and abnormal detrusor function.And the urodynamic test can provide objective clinical indicators for early diagnosis.

Objective:To investigate the role of short-term use of mycophenolate mofetil (MMF) in EB viral infection and acute graft-versus host disease (GVHD) in patients receiving haploidentical hematopoietic stem cell transplantation (haplo-HSCT) .Method:Adult patients (≥14 years) who were diagnosed with hematological malignancies received haplo-HSCT in Peking University Institute of Hematology from May 2016 to December 2017 were retrospectively reviewed. The median age was 30 (14-60) years old. A total of 498 patients including 277 males and 221 females were enrolled. Donors' median age was 38 (8-66) years old. All patients were classified into long-term use of MMF ( n=199), which was defined as 500 mg every 12 hours from day 9 pre-transplant to 250 mg every 12 hours from day 30 after transplant then withdrawal on day 45 to 60 after transplant, and short-term use of MMF ( n=299), which was defined as 500 mg every 12 hour from day 9 pre-transplant then withdrawal till neutrophil engraftment. Kaplan-Meier model was used to analyze the cumulative incidence of EBV infection, and the Cox proportional regression model for multivariate analysis. Result:Characteristics including sex, age, disease types, mismatched HLA loci, donor-recipient relationship, donor-recipient blood type, donor age, and donor sex were comparable between two groups (all P＞0.05). According to once, the incidence of EBV viremia, defined as EBV＞10 3 copies/ml at least once, in short-term group and long-term group was 19.4% (58/299) and 27.6% (55/199) respectively ( P=0.046).Donor age and the duration of MMF prophylaxis (short-term group as reference) were associated with EBV viremia according to multivariate analysis [ HR=1.022(95% CI 1.006-1.038),1.600(95% CI 1.059-2.418); P=0.006 and 0.026, respectively]. The incidence of grade Ⅱ-Ⅳ and Ⅲ/Ⅳ acute GVHD in long-term and short-term group was 32.2% (64/199) versus 20.7% (62/299)( P=0.005) and 10.1% (20/199) versus 8.0% (24/299) ( P=0.427), respectively. Donor sex (female as reference) and duration of MMF prophylaxis (short-term group as reference) were associated with grade Ⅱ-Ⅳ acute GVHD [ HR=1.908(95% CI 1.079-3.373),1.752(95% CI 1.161-2.643); P=0.026 and 0.008, respectively].There were no statistical differences in the incidence of CMV viremia, refractory CMV viremia and hemorrhagic cystitis (all P＞0.05) between the two groups. Conclusion:Short-term use of MMF can reduce EBV viremia without increasing the development of acute GVHD in haplo-HSCT patients.