1.Review of the problems encountered in the rehabilitation treatment for Wenchuan earthquake injuries
Chinese Journal of Hospital Administration 2008;24(11):725-727
An investigation was made on the rehabilitation treatment for the injuries wounded in Wenchuan Earthquake offered in 30 hospitals of 8 provinces, including Beijing, Shanghai, Jiangsu, Shandong, Hubei, Guangdong, Cbongqing, and Sichuan. On the basis of data from this investigation, the paper made analysis and summary of the challenges and problems encountered in the said rehabilitation treatment, and raises such recommendations as relessing rehabilitation assessment principles and policies for the injuries to return to their home towns in Siehuan, clarifying the responsibilities of individual government authorities in the later-stage rehabilitation treatment of the injuries, and enhanced synergy among respective disciplines and authorities of both clinical practice and rehabilitation treatment. The goal of these recommendations is further development of the rehabilitation medicine discipline in China.
2.The diagnostic value of electronic staining endoscopy combined with endoscopic ultrasound in the preopera-tive early gastric cancer
Chinese Journal of Primary Medicine and Pharmacy 2015;(6):811-812,813
Objective To evaluate the diagnostic value of electronic staining endoscopy combined with endo -scopic ultrasound(EUS) in the preoperative early gastric cancer .Methods A total of 17 patients diagnosed with intramucosal carcinoma by ordinary gastric endoscopy combined with pathological findings were selected ,who under-went the T staging by EUS and electronic staining endoscopic examination before ESD .The findings were compared with pathological findings.Results 17 cases were diagnosed with gastric cancer in T1 stage by EUS(12 cases limited mucous layer or mucosal muscular layer ,5 cases involving the submucossa ) .14 cases were diagnosed with gastric cancer in T1 stage by pathological examination (11 cases limited mucous layer or mucosal muscular layer ,3 cases involving the submucossa ) ,3 cases in T2 stage had received surgery .The accuracy of EUS in determining the depth of intramucosal carcinoma invasion was 88.2%;The total accuracy of T staging was 82.4%.The lesions border was more clear in electronic staining mode ,and easier marked.Conclusion The diagnostic value of electronic staining endoscopy combined with endoscopic ultrasound in the preoperative early gastric cancer is high .
3.Research progress on polyamine metabolism as a target for anti-cancer therapy
Qing WANG ; Yanlin WANG ; Chunyu CAO
Chinese Journal of Clinical Oncology 2014;(9):597-600
Rapid tumor cell growth depends on intracellular polyamine levels higher than those of normal cells. Intracellular polyamine depletion inhibits tumor cell proliferation and induces tumor cell apoptosis. Therefore, polyamine metabolism has recently been identified as an important target for anti-tumor therapy. This article briefly summarizes recent polyamine metabolism targeting, polyamine depletion within the tumor cells through a variety of methods, and the antitumor effects of the treatment.
4.Analysis on the size and income of off-staff medical workers at county-level hospitals in China
Zhong LIU ; Fei WANG ; Chunyu WANG
Chinese Journal of Hospital Administration 2016;32(5):369-372
Objective To learn the size and income of off-staff medical workers in a survey of public county-level general hospitals in China.Methods Human resources investigation of public county-level general hospitals,with SPSS data analysis of the outcomes.Results From 2011 to 2013,the proportion of off-staff medical workers increased from 31.44% to 36.69%,of whom the highest proportion was found in China′s western region,accounting for 40.69%;the ratio of off-staff practicing physicians increased from 14.24% to 16.64%,of whom China′s central region accounted for 19.92%;the ratio of off-staff nurses increased from 43.03% to 49.77%,of whom China′s western region accounted for 55.88%.In 13.7% of the hospitals,income of off-staff medical workers was less than a half of that for permanent staff;41.32% and 26.31% of the hospitals surveyed were fully covered with social insurance and housing fund account respectively.Conclusions Off-staff labor is a distinct feature at such hospitals,making imperative a HR system reform of public hospitals.The discriminative income and welfare between permanent and off-staff medical workers calls for a fundamental change to the income and welfare system.
5.Gender determination by Morphometry measuring of the 12th thoracic vertebra three-dimensional reconstruction image
Ning WANG ; Chunyu MIAO ; Jinxing LV
Chinese Journal of Forensic Medicine 2016;31(4):351-354
Objective This article aims to investigate the effect of gender determination for measuring the 12th Thoracic Vertebra by using computed tomography (CT) and explore the feasibility for the research of human skeleton measuring by CT technique in the ifeld of forensic anthropology.Methods After ascertaining 11 radial line indicators,we measured Multi-planner Reformation (MPR)image of the 12th Thoracic Vertebra. Four ratio indicators were calculated after eliminating measurement uncertainty of results. We inspected the effect of gender determination for measuring the 12th Thoracic Vertebra by using computed tomography (CT) on account of statistical measurement data.Results Gender determination of 12 indicators is remarkable after eliminating 3 unstable indicators. Sevene quations were established. The equation established by centrum indicators predicted sex up to 91.6% accuracy.Conclusion The morphometry indicators of 12th Thoracic Vertebra have gender difference. CT technology can accurately measure skeleton and is valuale for study of human skeleton measuring research in the ifeld of forensic anthropology.
6.Selection and evaluation of facial characteristic indexes of frontal photo for personal identiifcation(
Ning WANG ; Chunyu MIAO ; Jinxing LV
Chinese Journal of Forensic Medicine 2016;31(6):570-573
Objective This article aim to optimize facial characteristic indexes and to establish the standard of classiifcation by studying positive photos of Chinese Han nationality adults, and to investigate the personal identiifca-tion power ifnally. Methods Firstly, we determined the 27 facial characteristic indexes and standard of classiifcation. Secondly, we observed 254 positive photos of Chinese Han nationality adults. Finally, indexes and standard of classi-ifcation are evaluated through statistically analysising of observation data results and calculating personal identiifcation capability. Results Thirteen indexes gender differences are signiifcant. All 27 facial characteristic indexes are calculated. Male TDP(total discrimination power)=0.999 999 909 08, female TDP=0.999 999 919 82, overall TDP=0.999 999 868. Conclusion The more facial characteristic indexes and the more classiifcation and the higher degree of classiifcation, the higher personal identiifcation ability can be acquired.
7.Tendinopathy and the extracellular matrix:to deeply study the key proteins and enzymes in the bone-tendon junction
Chunyu LIU ; Xiaoyan HAN ; Lin WANG
Chinese Journal of Tissue Engineering Research 2016;20(15):2265-2272
BACKGROUND:In recent years, research on tendinopathy is becoming a hot topic in the sports medicine and rehabilitation, and the extracelular matrix plays a considerable role in the occurrence, development and healing of tendinopathy.
OBJECTIVE: To explore the relationship between tendinopathy and the extracelular matrix.
METHODS: CNKI, VIP, CBM, Wanfang, PubMed and Embase were retrieved for articles related to colagen, protein, glycoprotein and matrix remodeling published since 2000.
RESULTS AND CONCLUSION:After tendinopathy, there are obvious changes in colagen, proteoglycans, glycoprotein and related enzymes; and these changes also affect the reconstruction and repair of tendinopathy. Currently, most of researches focus on the tendon rather than the bone-tendon junction. This means that there are no in-depth studies on the correlation between many important proteins and tendinopathy, and the effects of exercise intervention.
8.Follow-up Study on Psychological Health Status and Glucose in Elderly Patients with Newly Ddiagnosed Type 2 Diabetes for One Year
Chunyu WANG ; Jianting ZHONG ; Dongjun WAN
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(02):-
Objective To investigate the characteristic of psychological health status and blood glucose in elderly patients with newly diagnosed type 2 diabetes for one year. Methods 48 patients in elderly with newly diagnosed type 2 diabetes were followed up on their blood glucose level and psychological status for one year. Results At newly diagnosed phase, fasting plasma glucose, 2 h postprandial plasma glucose and HbA1C were (9.48?2.67) mmol/L, (13.49?4.79) mmol/L and (8.89 ?2.74)%, but after 3months, those descended to (7.35?2.47) mmol/L, (10.01?3.14) mmol/L and (6.75?2.14)%, respectively. Compared with newly diagnosed phase, psychological happiness and living satisfaction improved; while the negative emotion, including depression, loneliness, hypochondriasis and anxiety, decreased consistent with the drop of blood glucose level after 3 months. Following 6 and 12 months, blood glucose and psychological heath status were stabilized on the whole. Conclusion Psychological status deteriorated seriously at newly diagnosed phase than in 3, 6 and 12 months, when is important phase for psychological intervention. Moreover, optimal glycemic control can promote psychological heath.
9.Study the distribution patterns of morphine in organs in rats with Acute morphine poisoning
Yaming SHAN ; Dayong WANG ; Chunyu HAO
Chinese Journal of Forensic Medicine 1987;0(03):-
In order to provide insights into sampling in suspected cases of morphine poisoning,the present study was conducted to investigate the distribution patterns of morphine in organs in rats with acute morphine poisoning at different post mortem intervals.Localization and semi quantitation of morphine in the brain,kidney,heart and liver were determined in rats at 15min to 5h after intravenous administration of morphine and at different intervals from 0 to 48h after death using the immunohistochemical SP method and image analysis.The results showed that the morphine could be detected in cytoplasms of certain parenchymal cells in all organs examined short time after delivery of morphine.With the extension of post delivery intervals,the level of morphine inereased,peaked,followed by decrease thereafter.The amount and the distribution patterns of morphine varied greatly with different organs.In the brain,the morphine could be detected earlier than in the heart,kidney and liver.It could detected 15min after the drug administration,with a peak,and disppeared at 5h after drug delivery.It decayed slowly as compared with the heart and lung.The kidney was the second organ in which the morphine was detected early with a high level and decayed slowly.In conclusion,immunohistochemical SP method can be used as a specific technique to detect morphine in organs in suspected cases of morphine poisoning.Both brain and kidney were the candidates for sampling in such case.
10.Polycyclic Aromatic Hydrocarbons Exposure and DNA Oxidative Damage in Traffic Policemen of Beijing
Qin WANG ; Chunyu XU ; Dongqun XU
Journal of Environment and Health 2007;0(09):-
Objective To explore polycyclic aromatic hydrocarbons(PAHs) exposure of traffic policemen in Beijing and its impact on DNA oxidative damage. Methods From Jun. to Aug. 2007,41 male traffic policemen and 34 male suburban inhabitants in Beijing were selected. The ambient fine particulate matter(PM2.5) was sampled within two consecutive days in the work places of traffic policeman and in the residential area of suburban inhabitants respectively . The levels of urinary 1-hydroxypyrene(1-OHP) and 10 PAHs species were both analyzed by high performance liquid chromatography(HPLC) . The levels of urinary 8-hydroxy-2’-deoxyguanosine(8-OHdG) were detected by ELISA kit,while the questionnaires for health information on smoking,drinking alcohol,exercise habit and so on were also inquired. Results The average levels of PM2.5,benzo[a]pyrene [B(a) P] and total PAHs in the traffic policeman group were 0.096 mg/m3,3.20 ng/m3,and 38.32 ng/m3 respectively,while the corresponding values in the suburban inhabitant group were 0.045 mg/m3,1.54 ng/m3 and 25.43 ng/m3 respectively. The concentration of urinary 1-OHP in the policeman group [(0.50 ?0.38 ) ?mol/mol Cr] was higher than that of the suburban inhabitant group([0.34?0.28) ?mol/mol Cr],P0.05. Multiple factors analysis indicated that urinary 1-OHP and smoking habit had influence on urinary 8-OHdG level,while there was no relationship with other factors(such as drinking alcohol,exercise and cooking habit) . Conclusion Traffic pollution may increase the level of DNA oxidative damage in policemen in Beijing.Traffic and smoking habit-related PAHs exposure is the important influencing factor.