1.Selection of delivery mode of uterine scar pregnancy
Jie SONG ; Lixia ZHEN ; Chunying FANG
Chinese Journal of Primary Medicine and Pharmacy 2015;(22):3457-3459,3460
Objective To investigate delivery mode of uterine scar pregnancy and analyze the safety of vagi-nal delivery.Methods 210 delivery women with scar uterus after cesarean section and 85 delivery women with non -scar uterus vaginal delivery of maternal selection were collected.According to the different ways of delivery,the preg-nant women in the scar group were divided into A group (72 cases)and B group (138 cases).Delivery outcome, maternal complications and average hospitalization time between the two groups were compared.Results 72 cases of maternal vaginal delivery in scar A group was successful and smooth vaginal delivery in 64 cases,and success rate was 88.89%(64 /72).8 patients maternal modified cesarean section production,accounted for 11.11%(8 /72),including 3 cases of persistent occiput posterior position,2 cases of social factors give up vaginal delivery,2 cases fetal distress, 1 case for incomplete rupture of uterus.138 cases delivery women in scar B group successfully obtained the cesarean section.100 cases of delivery women in non scar group,91 cases successfully got vaginal delivery,and the success rate was 91.00% (91 /100).Another 9 cases of delivery women were replaced with caesarean birth[9.00%(9 /100)],of which 3 cases of fetal distress,2 cases for fetal macrosomia,2 cases of persistent occiput transverse position,2 cases as social factors give up of vaginal delivery.Scar in group A maternal average hospitalization time was significantly shor-ter than scar in group B,and mean postpartum hemorrhage was significantly increased than scar in group B,and the differences were statistically significant (t =15.87,26.32,all P <0.05).There were no significant differences in the incidence of postpartum hemorrhage and neonatal asphyxia between the two groups (χ2 =0.24,1.05,all P >0.05). The maternal average hospitalization time,mean postpartum hemorrhage,postpartum hemorrhage and incidence rate of neonatal asphyxia between scar group A and non scar group had no significant differences (χ2 =0.88,1.30,1.03, 0.00,all P >0.05).Conclusion When choosing vaginal delivery in scar uterus again pregnancy,we should strictly grasp cesarean section pregnancy after vaginal delivery of the indications.Under strict monitoring,the safety of vaginal delivery was high.It was worth of clinical promotion.
2.Hepatic dysfunction during chemotherapy in breast cancer patients with positive HBsAg
Chunying ZHAO ; Jingling CHENG ; Qi FANG ;
Chinese Journal of General Surgery 2000;0(11):-
Objective To investigate the effect of chemotherapy on hepatic function in breast cancer patients with chronic hepatitis B virus (HBV) infection Methods In this study, 98 breast cancer patients received two to six courses of standard chemotherapy, alterations in hepatic function and blood HBV DNA level were measured and clinical symptom was observed Results (1) After two courses of chemotherapy, hepatic damage was observed in 36 84 % and 13 33% respectively in HBsAg positive and negative breast cancer patients ( P
3.The inhibitory effect of curcumin on the proliferation of HT-29 colonic cancer cell induced by deoxycholic acid
Bangmao WANG ; Chunying ZHAI ; Weili FANG ; Xin CHEN ; Kui JIANG ; Yuming WANG
Chinese Journal of Internal Medicine 2009;48(9):760-763
ay inhibit HT-29 cell proliferation, COX-2 mRNA transcription, COX-2 protein expression and PGE2 synthesis induced by DCA in HT-29 cell line. These data provide new insights into the mechanism of its anti-cancer properties.
4.Relationship between cognitive impairment and arterial stiffness in elderly patients
Xiangyang FANG ; Mei LU ; Jinling WU ; Hongyu NIU ; Chunying GAO ; Miaobing LIU
Chinese Journal of Geriatrics 2009;28(5):374-376
Objective To explore the relationship between cognitive impairment and arterial stiffness in elderly patients. Methods A total of 142 elderly patients were enrolled. Cognitive function was assessed by mini-mental state examination (MMSE) and arterial stiffness was assessed by pulse wave velocity (PWV). A full score on the MMSE was 30, and cognitive impairment was defined as a score less than 24. All subjects underwent the measurement of PWV and MMSE . The subjects were divided into 2 groups: 93 were assigned to the normal cognitive function group (MMSE score 24), and the remainders (n=49) were assigned to the cognitive impairment group (MMSE score 24). Results The PWV was significantly increased in the cognitive impairment group than in the normal cognitive function group [(13.3±2.4) m/s vs. (11.8±2.2) m/s, t=3. 775, P=0. 000]. Logistic regression analysis showed that the PWV was also independently and significantly associated with the MMSE score. Conclusions The increase of arterial stiffness is an important risk factor for impaired cognitive function in elderly patients.
5.Effects of Chinese Traditional Medicine on hemiplegia after stroke
Li-fang ZHU ; Hui-yu LIU ; Bi-qing DU ; Chunying ZENG
Chinese Journal of Rehabilitation Theory and Practice 2006;12(1):31-32
ObjectiveTo observe the effects of Chinese Traditional Medical therapy of supplementing Qi, nourishing Yin and strengthening genuine Qi on hemiplegia after stroke.Methods102 cases of hemiplegic patients were divided into 2 groups randomly, observational group (52 cases) and control group (50 cases), who were all treated with routine medicine and early rehabilitation. Observational group accepted Shenqi Fuzheng Injection or Shengmai Injection according to their syndrome for 28 days. Before and after treatment (within 3 days), simple Fug-Meyer Assessment Scale, modified Barthel index and gait analysis were used to evaluate the function of motor, activity of daily living (ADL) and walking.ResultsBoth groups improved their function of upper and lower limb's movement, ADL and walking significantly (P<0.001) after treatment. Compared with the control group, except for motor of upper limps, the patients in observational group improved their function more significantly (P<0.05).ConclusionChinese Traditional Medical therapy of supplementing Qi, nourishing Yin and strengthening genuine Qi may help the recovery of hemiplegia after stroke.
6.Effect of romethamine injection combined with uterine filling in the treatment of postpartum hemorrhage of preplacental cesarean section
Chinese Journal of Primary Medicine and Pharmacy 2018;25(12):1565-1568
Objective To investigate the effect of romethamine injection combined with uterine filling in the treatment of postpartum hemorrhage of preplacental cesarean section .Methods From May 2014 to March 2017 , 100 cases of placenta previa cesarean section postpartum hemorrhage in Jiande Maternal and Child Health Care Hospital Obstetrics and Gynecology were selected as the research objects , and they were randomly divided into observation group and control group according to the digital table ,with 50 cases in each group .The observation group received romethamine injection combined with uterine filling treatment ,the control group received oxytocin combined with uterine cavity filling treatment .The clinical curative effect of the two groups was compared .Results The blood loss during delivery between the two groups had no statistically significant difference ( t =1.335, P >0.05 ). Postpartum 2h and 24h,the blood loss of the observation group were significantly lower than those of the control group [(657.58 ±63.21)mL vs.(875.23 ±65.42)mL,(712.52 ±64.32)mLvs.(958.12 ±74.66)mL],the differences between the two groups were statistically significant (t=8.265,11.356,all P<0.05).Before and after treatment,the heart rate , blood pressure and blood oxygen saturation between the two groups had no statistically significant differences ( t =3.255, 2.365, 3.255, 2.365, t =3.365, 2.658, 4.365, 1.654, all P >0.05 ). Conclusion Romethamine injection combined with uterine filling in the treatment of postpartum hemorrhage of preplacental cesarean section has significant effect ,it is worthy of application .
7.Principle of Mapping out and Implementing of Rehabilitation Clinical Pathway
Jianjun LI ; Mingliang YANG ; Yongqing HUANG ; Hongjun ZHOU ; Chunying HU ; Fang CONG ; Zhuoying QIU ; Degang YANG ; Qiang LI ; Chao CHEN
Chinese Journal of Rehabilitation Theory and Practice 2012;18(1):90-91
In 2009, Ministry of Health mapped out the Guiding Principle of Clinical Pathway. Rehabilitation is different with early treatment of common diseases. This paper mainly introduces the objective of rehabilitation clinical pathway, organization of management system,guiding principle of mapping-out and implementation and evaluation and improvement of medical quality.
8.Epidemic and clinical characteristics of measles in Northeast China in 2014:an analysis of 1 401 cases
Yuguang YAN ; Yumei MA ; Ni WEI ; Mingxiang ZHANG ; Baiyila HAN ; Yanbo WANG ; Chunying JIN ; Leqiang HAN ; Yongxiang ZHAO ; Yuzhi CAO ; Hong FANG ; Hao HU ; Zheng LIU
Chinese Journal of Clinical Infectious Diseases 2015;(5):419-424
Objective To investigate the epidemiological and clinical characteristics of measles in patients of different age groups in Northeast China in 2014.Methods The clinical data of patients with measles in ten hospitals of infectious diseases in Northeast China from January 2014 to June 2014 were collected.Patients were divided into <16 age group and ≥16 age group, and the epidemiology , clinical characteristics, treatment and prognosis of all patients were retrospectively reviewed .SPSS 17.0 was used for data analysis.Results There were 1 401 patients with measles, in which 402 were <16-year old, and 999 were ≥16-year old.Clinical manifestations were mainly maculopapule (100.0%), fever (84.58%), cough (85.80%), Koplik’ s spot (73.23%), pharyngeal hyperemia (71.23%), diarrhea (43.97%), expectoration (40.97%), tears (39.40%) and runny nose (30.55%).The incidences of Koplik’s spot, sputum, pharyngeal hyperemia and diarrhea in <16 age group were lower than those in ≥16 age group (χ2 =8.364, 29.768, 10.953 and 6.701, P<0.05 or <0.01); while the incidence of runny nose was higher than that in ≥16 age group (χ2 =6.703, P<0.05).Abnormalities were found in blood routine examination, C-reactive protein (CRP), liver and kidney function, serum electrolyte levels, myocardial enzymes, and so on.Increasing in WBC, PLT and creatine kinase isoenzyme (CKMB), and decreasing in WBC were observed in 38(9.45%), 122(30.35%), 279(69.40%) and 105(26.12%), patients in <16 age group, which were higher than those in ≥16 age group [45(4.5%), 14(1.40%), 347(34.73%) and 202(20.22%)], and the differences were of statistical significance (χ2 =12.593, 274.033, 139.385 and 5.830, P<0.05 or P<0.01).Increasing in alanine aminotransferase (ALT), CRP, total bilirubin level (TBil), creatine kinase (CK), and decreasing in albumin (Alb), K+, Na+, Cl-were observed in 70(17.41%), 7(1.74%), 38(9.45%), 7(1.74%), and 214(53.23%), 59(14.68%), 45(11.19%), 94(23.38%) patients in <16 age group, which were lower than those in ≥16 age group [668(66.87%), 89(8.91%), 277(27.73%), 714(71.47), and 268(26.83%), 339(33.93%), 642(64.26%), 450 (45.05%)], and the differences were of statistical significance (χ2 =281.230, 23.073, 50.687, 159.740, and 14.674,114.286, 44.268, 271.546, P<0.01).Laryngitis and pneumonia were the most common complications.The incidence of laryngitis in <16 age group was 12.69% (51/402), which was higher than that in ≥16 years group (93/999, 9.31%,χ2 =3.545, P<0.05);while the incidence of spot shadows demonstrated by X-ray in <16 years group ( 72.89%, 121/166 ) was higher than that in ≥16 years group (265/445, 59.55%,χ2 =9.249, P<0.01).Conclusions There are differences in clinical features of measles in patients between <16 age group and ≥16 age group.Basic immunization in children and revaccination in adults should be enhanced to control the epidemics of measles .
9.A study of prospect and review on risk assessment tools for deep vein thrombosis
Du HONG ; Jun XU ; Chunying WANG ; Ping LU ; Jun FANG ; Yu CHEN
Chinese Journal of Practical Nursing 2018;34(35):2796-2800,封3
Deep venous thrombosis (DVT) is an acute critical disease with high clinical incidence and easy to be misdiagnosed and missed. Not early assessment and effective prevention, it is very easy to lead to the occurrence of post thrombotic syndrome and pulmonary embolism, with high mortality and a serious threat to the life safety of the patients. The early and effective individual assessment of the DVT risk assessment tool is the basis for risk stratification and appropriate preventive measures. It is the key to reduce the incidence of DVT, misdiagnosis rate, missed diagnosis rate, incidence of complications and mortality. This paper is to review the research progress of individual DVT risk assessment tools at home and abroad, with a view to the same kind. The development of the research can be used for reference.
10.Clinic and Rehabilitation Pathway Recommendation for Spine and Spinal Cord Injury
Mingliang YANG ; Jianjun LI ; Qiang LI ; Zhuoying QIU ; Chao CHEN ; Feng GAO ; Liangjie DU ; Hongjun ZHOU ; Chunying HU ; Fang CONG ; Yongqing HUANG ; Degang YANG
Chinese Journal of Rehabilitation Theory and Practice 2012;18(8):791-796
Objective To establish the proposals of clinic and rehabilitation pathway for spine and spinal cord injury. Methods The experiences in clinic and rehabilitation treatment fields, the flow path of admission and the costs of hospitalization for spine and spinal cord injury patients in Chinese Rehabilitation Research Center were retrospectively summarized and analyzed. Related data in International Classification of Functioning, Disability and Health (ICF) core sets were also referred. Results The present proposals were applied to patients suffered from thoracic, lumbar or sacral spine injury with spinal cord injury. The proposals consisted of two parts: the surgical interventions in acute stage (within 2 weeks after injury) and clinic and rehabilitation treatments of spinal cord injury in sub acute and later stages (2 weeks to 6 months after injury). The criteria of surgical interventions in acute stage materialized the core therapies such as reconstruction of spine stability and neural decompression, etc. The criteria of treating spinal cord injury in subacute and later stages demonstrated the characteristic of combined therapy in which rehabilitation was the central element. Conclusion The establishment and implement of the present pathways were based on the time course of disease development and the staging feature of neural recovery and treatment after spinal cord injury. The purpose of this work is to improve the quality of medical service and reduce medical consumption.