2.Systemizing effect study on obsessive-compulsive symptoms and autism-spectrum quotient among college students
Chunyan YANG ; Hongwei SUN ; Xiumei HOU
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(3):258-260
Objective To investigate the correlations between obsessive-compulsive symptoms and autism-spectrum quotient and explore if systemizing is the mediator between them. Methods With Padua Inventory (PZ) ,AQ and Systemizing Quotient (SQ), 1901 college students were assessed with stratified random sampling survey. Results Compared with the femal students, score of systemizing in male students had a significant increase ( (26. 773 ± 9.225 )vs (22.017 ± 7 ± 934), P <0.01 ). AQ total score was significantly positive correlated with PI total score( r=0. 336, P<0.01 ),and correlation was also found among SQ,AQ and PI in different degrees. the mediating effect of systemizing was significant. The regression equation was AQ = 18. 942 +0. 064PI -0. 022SQ (P < 0.01 ). Conclusion There are positive correlation between obsessive-compulsive symptoms and AQ in college students, and systemizing is the mediator between above symptoms.
3.Study Status of Quality Control and Analysis Methods for Vitamin C Injections
Chunyan SUN ; Tianming DING ; Ninglin CHEN
China Pharmacist 2014;(5):868-870
Vitamin C injections are a national essential drug with wide clinical applications and instable property. In order to pro-vide the reference for further analysis on the quality status of vitamin C injections and improve the quality,the research on the stability, quality control and analysis methods was summarized in the study.
4.Therapeutical Effect of Tangkening on Glucose and Lipid Metabolism of Rats with Diabetes Mellitus
Xuedong SUN ; Chunyan LIU ; Niuyan CHEN
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(02):-
0.05). Conclusion Tangkening may be another therapy choice of Diabetes.
5.Mitigation of safflor yellow injection on acute lung injury of rats induced by oleic acid
Chongqiang PEI ; Chunyan SUN ; Ming JIN
Chinese Traditional and Herbal Drugs 1994;0(04):-
Objective To investigate the effects of safflor yellow (SY) injection on acute lung injury (ALI) rats induced by oleic acid (OA) and its potential mechanism. Methods Wistar rats were randomly divided into six groups,including control group,OA group,OA+10 mg/kg anisodamine group,OA+8 mg/kg SY group,OA+16 mg/kg SY group,and OA+32 mg/kg SY group. Normal saline or anisodamine or SY were pretreated before 0.18 g/kg OA iv injection. The arterial partial pressure of oxygen,the pulmonary water content index,and MPO activity in lung tissue were determined; The mRNA level of TNF-?,IL-1?,IL-6,ICAM-1,and VCAM-1 were measured by RT-PCR; And NF-?B p65 protein in nucleus observed by immunohistochemical technology,while the level of p38 MAPK protein phosphorylation in lung tissue was analyzed by Western blotting. Results The arterial partial pressure of oxygen in all SY groups was higher than that in OA group,while the pulmonary water content index and MPO activity were lower than those in OA group,as well as the mRNA level of the above inflammatory cytokines and the NF-?B p65 in nucleus and level of p38 MAPK phosphorylation. Conclusion SY could alleviate the lung tissue edema,increase the arterial partial pressure of oxygen,and depress MPO activity in ALI rat induced by OA. The SY mechanism of attenuating the acute lung injury may be associated with inhibiting the p38 phosphorylation and NF-?B activation and reducing inflammatory factors expression.
6.Impact of Stimulation Parameters on Event-related Potential P300
Chunyan MAO ; Li SUN ; Yuan YUAN
Chinese Journal of Rehabilitation Theory and Practice 2016;22(7):821-823
Objective To observe the latency and amplitude characteristics of event-related potential P300 under different target stimu-lus. Methods During January to December, 2014, 35 patients with memory impairment received P300 test under the percentage of target stimuli of 0.10 and 0.25. The latency, amplitude and area under amplitude were compared. Results There was no significant difference in la-tency (t<0.256, P>0.800), but the amplitude and area under amplitude increased under 0.10 compared with those under 0.25 (t>4.259, P<0.05). Conclusion Less target stimulation may improve the patients' attention and increase amplitude of P300, but no more interference in la-tency, suggesting latency of P300 is more stable for assessment of cognitive function.
8.The effect of tripterygium wilfordii on proteinuria in patients with diabetic nephropathy
Chunyan NIE ; Liming CHEN ; Baocheng CHANG ; Miaoyan ZHENG ; Chunyan SHAN ; Wenqiang SUN
Chinese Journal of Practical Internal Medicine 2001;0(06):-
0.05).Conclusion Tripterygium wilfordii,combined with routine treatment,appeared to decrease 24-hour proteinuria in a certain extent and did not adversely affect liver function,renal function and the blood routine test in most patients with diabetic nephropathy.
9.Investigation and analysis in the sexual life quality of females at the reproductive ages after cervix cancer operation
Meiling SUN ; Chunyan MENG ; Meimei LIU ; Li LU
Chinese Journal of Practical Nursing 2008;24(9):16-17
Objective To explore the sexual life quality of females at the reproductive ages after cervix cancer operation and supply evidence for establishment of correspondindg nursing measure. Methods We investigated the frequency of sexual life and satisfaction degree of sexual life in 40 females at the reproductive ages after cervix cancer operation by face-to-face investigations using questionnaires before and 4 months after operations. Then the difference of sexual life quality before and after operation were compared and analyzed. Results The frequency of sexual life (P<0.01,P<0.05) and satisfaction degree of sexual life (P<0.01,P<0.05) were evidently decreased. The sexual life quality was lower than that before operation. Conclusion The sexual life quality could be affected by many factors such as economic conditions, culture background, sexual conceptions and the attitude of their partners.
10.The changes of lymphocyte subsets in patients with severe sepsis and the effect of Ulinastatin
Jinyan XING ; Xiaoning HAN ; Yunbo SUN ; Min LUAN ; Chunyan DV
Chinese Journal of Emergency Medicine 2006;0(05):-
Objective To investigate the effects of ulinastatin on the number of peripheral blood lymphocyte and the percentage of its subsets in patients with severe sepsis. Methods The scores of APECHE II and SOFA, the number of lymphocyte and the percentage of different subsets in these sepsis patients at different treatment time were measured. Results After treatment, the scores of APECHE II and SOFA of severe sepsis patients were decreased, the number of lymphocyte elevated and the percentages of different subset were corrected. Sepsis caused by Gram- positive pathogens had stronger suppression of peripheral blood lymphocyte and subsets compared with Gram - negative pathogens. Conclusion Patients with severe sepsis had less peripheral blood lymphocyte and abnormal subsets. Ulinastatin could help to correct such abnormality.