Objective:To understand the levels of serum cholesterol in patients with gastric cancer and gastric ulcer before and after operation,and to study the relationship between the level of serum cholesterol and the tissues differential degree of gastric cancer.Methods:To survey the content of serum cholesterol in patients with gastric cancer and patients with gastric ulcer confirmed clinically before and after operation,looking through the medical records of the patients and taking notes about the tissues differentiated degree of the gastric cancer,then making the statistical analysis.Results:Comparing with the normal control group,the level of serum cholesterol in gastric cancer decreased obviously before operation,there was obvious statistical difference(P0.01),and increased after operation,comparing with themselves before operation was statistical difference(P0.05),and no statistical difference comparing with the normal control group after operation.There was statistical difference between the higher(group A)and the lower(group B)differentiated degree of gastric cancer tissues(P0.05)before operation and no statistical difference after operation.After operation the levels of serum cholesterol in group A and group B were all increased.Comparing with the level of serum cholesterol before operation each other,there was obvious statistical difference(P0.01)in group B and no statistical difference(P0.05) in group A.Conclusion:The level of serum cholesterol in patients with gastric cancer decreased before operation and increased after operation,especially in progressive gastric cancer.There was correlation between the level of serum cholesterol and the tissues differentiated degree of gastric cancer.The lower the tissues differentiated degree of gastric cancer was,the lower before operation and the higher after operation the level of serum cholesterol were.

Objective To investigate the treatment effectsand safety of ifosfamide,nedaplatin with pharmorubicin in relapsed ovarian carcinoma.Methods Sixteen relapsed ovarian carcinoma patients received nedaplatin 150mg in 0.9% sodium chloride 500ml dl,intravenously;pharmorubicin 40mg in 5% glucose 50 ml d1-2,intravenously;and ffosfamide 2.0g in 0.9% sodium chloride 500ml d1-5,intravenously.And the treatment effects and side effects were investigated.Results Of the sixteen patients,one had a complete response,six had a partial response,seven had stable disease,and two had progressive disease.The overall response rate was 43.75%(7/16).The major side effects were bone marrow suppression and gastrointestinal reaction.Conclusion Combination of ffosfamide,nedaplatin and pharmorubicin were very effective in relapsed ovarian carcinoma and the side effects were tolerable.Therefore the regimen is worth promoting in the clinical application.

OBJECTIVE To investigate the distribution and resistance rate of clinical isolates from neonatal sepsis in Hubei hospitals.METHODS The antimicrobial susceptibility of clinical isolates from(neonates) blood culture derived from sixteen hospitals in Hubei from 2000 to 2004,was retrospectively analyzed and tested by KirbyBauer(method).RESULTS A total of 1 019 strains were isolated from blood specimens,Gram-positive and Gram(-negative)(bacteria) accounted for 93% and 7% of these isolates,respectively.The main isolates were coagulase(-negative) staphylococci(CNS,79.8%),Enterococcus spp(7.0%),Staphylococcus aureus(SAU4.5%),Klebsiella spp(1.7%),Stenotrophomonas maltophilia(1.2%),and Escherichia coli(0.9%).71.3% CNS and 19.6% SAU were meticillin resistant,46.5% enterococci resistant to ampicillin and almost strains were susceptible to(vancomycin)(except E.gallinarum).ESBLs were detected in isolates of 56% E.coli and 35% K.pneumoniae.S.maltophilia was susceptible to trimethoprim(-sulfamethoxazole) and levofloxacin with resistance rate of 8.3% and 0%.In strains of other Gram-negative rods,resistance rate to imipenem,amikacin and fluoroquinolones were detected between 0% to 15%,and to cephalosporins Ⅰ-Ⅳ were between 20% to 70%.CONCLUSIONS Gram-positive cocci are important pathogens in neonatal sepsis,antimicrobials should be used on the result of(antimicrobial) susceptibility test.It is more important to reduce health care-associated(nosocomial) infections.

The defects in management and application of medical equipment and apparatus are analyzed. According to different conditions, countermeasures are put forward. Operators should know the operation requirements and using characteristics and equipment keepers should tighten up the management. The application detail of the medical equipment is the basis of medical security.

Objective: To evaluate biological materials tanned with a compound method for clinical performance of biovalves. Methods: The tissue calcium concentration was compared between biological materials tanned simply with amylic aldehyde and those compoundly tanned with amylic aldehyde, cation fat, chromium trioxide and glycerol. The histological morphology, the ultra-structure and tensile strength of the biological materials were tested and the content of hydroxyls in the materials was measured with the Fourier infrared spectrum detector. The prosthetic biological cardiac valves made of the materials were tested with an accelerated wearing device extracorporeally. Results: The tissue calcium concentration was lower in the compoundly tanned materials. In these materials, the collagenous fibers were dense and lined up in order. The cellular structure was maintained. The materials were pliable at the contracting temperature of 86℃ to 90℃. The tensile strength of the materials was 19.9 to 25.9 N/mm 2 and the extension rate was 43.4% to 46.0%. The peak of the hydroxyls decreased significantly at the wave length of 1741.11 cm -1 in the Fourier infrared spectrum. The swine aortic valve experienced 3.892?10 8 cycles in the accelerated wearing tests, and the bovine pericardial valve, 3.888?10 8 cycles. By estimation, the biovalves will last for about ten years. Conclusion: Compound tanning can increase firmness and softness of the materials and may play an important role in anticalcification of the biovalves.

Objective To evaluate the level of serum cholesterol in patients with progressive gastric cancer and gastric ulcer before and after operation, and the relationship between the level of serum cholesterol and the clinical differential degree of progressive gastric cancer . Methods To measure the content of serum cholesterol in patients with progressive gastric cancer and gastric ulcer before operation and after operation 10 day. The size of tumor, infiltration, metastasis and the pattern of the operation were studied statistically. Results The level of serum cholesterol in group of progressive gastric cancer was significant lower than that of normal control group(P 0.05 ) in group A, but there was significant difference in group B after the operation(P

Objective:To determine the relationship between brachia l artery blood pressure and radial artery blood pressure in children and whether blood pressure measured from the radial artery can replace blood pr essure measured from the brachial artery. Methods:Brachial and rad ial artery pressures in 105 children were measured using an electronic sphygmomanometer.Results:There was no significant difference between the average values of blood pressures of the brachial and radial arteries in the 105 children studied (P>0.05). Linear regression and correlation analyses showed that there was a positive linear correlation between the systolic pressure of the b rach ial artery and the radial artery in the 105 children, as well as a posit ive linear correlation between the diastolic pressures of the brachial and the radial arteries. Conclusion:Blood pressure values from the radial artery can completely replace blood pressure values from the brachial artery.

Objective To determine the validation of measuring blood flow velocity intravascularly using a new Doppler microprobe. Methods Catheterization and signal recording were investigated using a new 0.3 mm diameter microprobe in 40 patients during routine cerebral angiography (45 vessels). Blood flow velocity was determined using this technique (intravascualar Doppler sonography, IVDS) in another 14 patients with femoral-popliteal stenosis before and after percutaneous transluminal angioplasty (PTA). Results IVDS was successful in 95.6% healthy vessels (43/45) and recorded the same typical flow-pulse curve as seen in transcutaneous measurement. Measurement of blood flow velocity was successful in 12 out of 14 patients (86%) with femoral-popliteal stenosis before and after PTA. IVDS could verify that blood flow velocity increased significantly after successful PTA (t= 4.01, P

Objective:To study the validity of MMPI in police recruitment.Methods:9096 police applicants had been tested with MMPI from 1989 to 2004.Results:1694 male applicants were not accepted, they got higher MMPI(Chinese version) T-scores on scale Hs(61.9?10.0/45.4?6.6,t=8.76), Pa (61.6?12.7/46.6?8.1,t=5.85), Pt (58.7?10.1/43.3?7.6,t=6.45), Sc (65.4?7.8/44.6?6.6,t=11.46), and Ma, so did the female ones on scale Pt (60.9?3.7/42.2?8.2 ,t=3.79), Sc (68.9?3.0/45.2?8.2,t=4.96), and Ma (63.5?4.1/50.1?9.2, t=2.48). After a 16-year follow up, the results showed that in the group enrolled, none had suffered mental illness. 43 out of 70 applicants who were not accepted during 1989 to 1990 were investigated. Two of them had been sent to psychiatric hospital for schizophrenia.Conclusion:Result of MMPI is valuable in police recruitment.

AIM: To study the blood quickening and stasis dispelling effect of the different processed products of Rhizoma Curcumae by rat's platelet aggregation in vivo and its hemorrheological properties and blood coagulation. METHODS: The platelet aggregation determination, hemorrheological properties determination and mice blood coagulation method were used to observe the blood quickening and stasis dispelling effect of the different processed products of Rhizoma Curcumae. RESULTS: The different processed products of Rhizoma Curcumae all had some inhibition on platelet aggregation, anticoagulation and improvement on the hemorrheological parameters. Among all of them, the processed product with vinegar was the most strong. CONCLUSION: In traditional processes, pharmacological test shows that Rhizoma Curcumae processed with vinegar has the best effects.