Objective To discuss the meaning and association with prognosis of Bcl-w expression in gastric carcinoma. Methods By Immunohistochemistry( SP) method was used to detect the expression of Bcl-w and MMP-2 in 100 cases of human gastric carcinoma. Results (1) Among 100 cases of stomach carcinoma, Bcl-w and MMP-2 positive expression rates were respectively 69. 0% , 77. 0% ; (2) The Bcl-w and MMP-2 expression in gastric carcinoma was positively associated with tumor size, invasive depth, histology differentiation and lymph node metastasis(P<0.05) ;(3)The expression of Bcl-w was significantly correlated with MMP-2 in gastric carcinomas (P =0.002) ; (4) Five years survival rates and overall survival of Bclw-positive patients were lower than the Bcl-w -negative patients. Conclusions (1)Bcl-w plays an important role in inhibiting apoptosis of gastric cancer and promoting gastric cancer invasion; (2) Bcl-w-positive expression patients have a bad prognosis and Bcl-w expression in gastric carcinoma can be regarded as a prognosis evaluation index.

Dental implantation is a popular way to replace natural teeth. Its prognosis is affected by a number of factors including periodontitis. A large number of studies have shown the incidence of peri-implant disease and implant failure rate in periodontal compromised patients are higher than periodontal healthy patients. Peri-implant disease is closely related to the pathogens in periodontitis. What's more, the long-term success of dental implants is affected by multiple risk factors of periodontitis such as regular oral hygiene maintenance and smoking. This paper reviews the survival rate, the pathogens and the prognosis of implants in periodontal compromised patients.