1.Clinical characteristics and radiological manifestations of immune reconstitution inflamnmtory syndrome in acquired immunodeficiency syndrome patients with tuberculosis during Mghly active antiretrovirai therapy
Chunwang YUAN ; Dawei ZHAO ; Lianchun LIANG ; Zaicun LI ; Feng CHEN ; Yong DUAN ; Wei WANG
Chinese Journal of Radiology 2008;42(2):149-151
ObjectiveTo explore the clinical characteristics and radiological manifestations of immune reconstitution inflammatory syndrome(IRIS)in acquired immunodeficiency syndrome(AIDS)patients with tuberculosis(TB)during highly active antiretroviral therapy(HAART).MethodsThe clinical and radiological data in 4 AIDS patients with TB who presented IRIS were analyzed retrospectively.ResultsThe clinical presentations of IRIS in 4 patients included fever(4 cases),weakness and weight loss(3 cases),abdominal pain(2 cases),cough with sputum(1 case),dyspnea(1 case).Cervical and(or)supra-clavicular lymph node enlargement were seen in 3 patients,inguinal lymph node enlargement in 1 patient,abdominal lymph node enlargement in 1 patient,hilar or mediastinal lymph node enlargement in 2 patients,pulmonary parenchyma and liver were involved in 2 patients,the involvement of kidney,adrenal gland,mesentery,peritoneum,psoas,brain and cutis was respectively found in 1 patient.The clinical and radiological presentations of IRIS were temporary and self-limited,improvement can be seen with antituberculosis therapy and HAART. ConclusionsIt is possible to have IRIS during HAART in AIDS patients with TB.Imaging examinations play an important role in the early diagnosis,monitoting and evaluating the response to therapy of IRIS.
2.Early X-ray and CT appearances of severe acute respiratory syndrome: an analysis of 28 cases.
Dawei ZHAO ; Daqing MA ; Wei WANG ; Hao WU ; Chunwang YUAN ; Cuiyu JIA ; Wen HE ; Chunhong LIU ; Jianghong CHEN
Chinese Medical Journal 2003;116(6):823-826
OBJECTIVETo study the early X-ray and CT findings of patients with severe acute respiratory syndrome (SARS).
METHODSChest radiography and CT were performed in 28 patients with SARS within one to three days after onset of the disease. CT examinations included conventional spiral CT and high-resolution CT (HRCT). The radiographic and CT findings of these patients were analyzed retrospectively.
RESULTSAbnormal CT findings were noted in all the patients, but abnormal chest radiographic findings in 17 cases (60.7%, 17/28). CT showed single small focal patchy opacities in 23 patients (82.1%, 23/28), including oval ground-glass opacities in 20 patients, lobular distribution ground-glass opacities in 2 and small patchy consolidation in one. Multi-focal ground-glass opacities were found in 2 patients and extensive opacities in three. In the 28 patients, a total of 31 lesions were found in the upper (7, 22.6%), middle (3, 9.7%), and lower lobes (21, 67.7%). The diameter of the lesions ranged from 20 to 35 mm.
CONCLUSIONThe dominant feature of early SARS patients is focal patchy opacity in the lung, and oval small ground-glass opacities are the common morphological findings on CT.
Adult ; Female ; Humans ; Male ; Middle Aged ; Radiography, Thoracic ; Severe Acute Respiratory Syndrome ; diagnostic imaging ; pathology ; Tomography, X-Ray Computed
3.Transcatheter hepatic arterial chemoembolization combined with CT guided radiofrequency ablation for treatment of primary liver cancer in caudate lobe
Shoupeng SHENG ; Bin SUN ; Jiasheng ZHENG ; Xiongwei CUI ; Shichang CUI ; Chunwang YUAN ; Zhiling QIAN ; Jianjun LI ; Cong LI ; Honghai ZHANG ; Liang MA
Chinese Journal of Interventional Imaging and Therapy 2017;14(7):391-395
Objective To evaluate the efficacy and safety of transcatheter hepatic arterial chemoembolization (TACE) combined with CT guided radiofrequency ablation (RFA) for primary liver cancer in the caudate lobe.Methods Sixteen patients with primary liver cancer in the caudate lobe were treated with combination therapy of TACE and RFA.Complet ablation rate,overall and recurrence-free survival,and complications were evaluated.Results A total of 15 cases achieved complet ablation,complet ablation rate was 93.75% (15/16).Recurrence-free survival time was 19.35 months,overall survival time was 44.62 months.Overall survival rates were 88.23%,66.65% and 33.18% at 1,3,5 years after therapy,respectively.Conclusion TACE combined with RFA is a safe and useful therapeutic option for treatment of primary liver cancer in the caudate lobe.