1.Application of attention distraction in nursing children with maxillofacial trauma
Modern Clinical Nursing 2014;(12):35-37
ObjectiveTo explore the effect of attention distraction in nursing children with maxillofacial trauma. Method Eighty-eight children with maxillofacial trauma were divided into control group and observation group with 44 patients in each group.Patients in the observation group was cared with attention distraction while the control group by traditional method of forced bondage.The two groups were compared in terms of wound treatment time and healing time,comfort degree and compliance of children.Results The wound treatment time and healing time in the experiment group were shorter than those in the control group.The comfort degree and compliance of children in the observation group were better than those in the control group(P<0.05).Conclusion Attention distraction for nursing children with maxillofacial trauma can improve children’s comfort and treatment compliance and shorten treatment time.
2.Safety management of infusion pumps in clinical use
Chinese Medical Equipment Journal 2004;0(07):-
Objective To provide a help in avoiding accidents related to infusion pump by analyzing its causes and preventive measures. Methods Alarms of infusion pump occurred in 59 patients by infusion pump are reviewed retrospectively and measures to prevent accidents related to infusion pumps are summarized. Results The measures effectually prevent accidents and guarantee patients in using infusion pump. Conclusion The accidents related to infusion pumps can be prevented effectioly by enhancing safety management and making nurses familiar with the infusion pumps,their alarms as well as handling methods.
3.Determination of Related Substances in Pediatric Paracetamol Artificial Cow-bezoar and Chlorphenamine Maleate Granules by HPLC
China Pharmacist 2014;(12):2154-2155,2156
Objective:To establish an HPLC method for the determination of p-aminophenol in pediatric paracetamol artificial cow-bezoar and chlorphenamine maleate granules. Methods: A CAPCELL PAK MGⅡC18 (150 mm × 4. 6 mm,5 μm) chromatographic column was used with 0. 05% ammonium acetate solution-methyl (85∶ 15) as the mobile phase at the flow rate of 1 ml·min-1 , the detection wavelength was 232nm,the injection volume was 10μl,and the column temperature was 30℃. Results:The linear range of p-aminophenol was 9. 878 4-197. 568 0 ng(r = 0. 999 1), the average recovery was 99. 8%(RSD = 0. 9%,n= 9), and detection limit was 2ng. Conclusion:The method is simple, specific and accurate, which can be used to determine the contents related substances in of pediatric paracetamol artificial cow-bezoar and chlorphenamine maleate granules.
4.Compare the effects of combined nerve block and epidural anesthesia in elderly patients undergoing unilaternal total hip replacement surgery
Chinese Journal of Postgraduates of Medicine 2010;33(14):21-23
Objective To compare the effects of combined lumbar plexus-sciatic nerve block and epidural anesthesia in elderly patients undergoing unilatemal total hip replacement surgery. Methods Fortytwo patients were randomly divided in two groups (each in 21 cases),combined lumbar plexus-sciatic nerve block group (group N) and epidural anesthesia group (group EA). In group N, combined lumbar plexussciatic nerve block guided by a nerve stimulator was conducted,with 1% lidocaine 15 ml and 0.5% ropivacaine 20 ml (lumbar plexus) and 1% lidocaine 5 ml and 0.5% ropivacaine 20 ml (sciatic nerve). In group EA,epidural anesthesia was achieved by injection of 0.5% ropivacaine 10-15 ml. The variations in hemodynamics, the effect of never block and adverse reactions in both groups were recorded. Results The blood pressure was decreased significantly in group EA than that in group N at 10,20,30,60 min after epidural anesthesia (P <0.05). There was no difference in the onset time of sensory and motor blockade between two groups (P >0.05),while the duration of sensory and motor blockade was longer in group N [(436.5 ± 103.3 ), ( 307.3 ± 112.4 ) min ] than those in group EA [ (305.2 ± 110.8), ( 189.3 ± 84.5 ) min ](P < 0.05). There was 4 patients combined nausea and vomiting in group EA. Conclusion Combined lumbar plexus-sciatic nerve block in elderly patients undergoing unilaternal total hip replacement surgery has stable hemodynamics, longer analgesia duration and fewer adverse reactions.
5.The research of variation of T lymphocyte subsets and serum immunoglobulin for perioperative patients with thyroid cancer
Chinese Journal of Primary Medicine and Pharmacy 2011;18(21):2895-2896
ObjectiveTo investigate the variation of T lymphocyte subsets and serum immunoglobulin for perioperative patients with thyroid cancer.Methods74 cases in our hospital for radical surgical resection treatment and 131I treatment after surgery were chosen as the observation group.Take the level of T lymphocyte subsets and serum immunoglobulin for statistics.And then compared with 40 healthy people.ResultsThe observation group before surgery:NK cells:( 19.1 ± 4.6) %,T cells:(68.2 ± 5.5 ) %,the serum immunoglobulin before surgery was ( 13.4 ±1.4μg/L).It was significantly higher than the control group [ ( 15.2 ± 3.2 ),( 65.2 ± 5.2 ),( 4.3 ± 0.5 ) ] ; CD4+(32.1 ± 2.9),CD4+/CDs+ ( 1.1 ± 0.3 ).It was significantly lower than the control group ( 38.1 ± 3.9,4.3 ± 0.5 ).The difference was statistically significant ( t =24.5,17.8,33.6,14.5,22.5,all P < 0.05 ).The observation group after surgery,1 month after 131I treatment,3 months after 131I treatment,NK cells ( 17.0 ± 3.3 ),( 16.9 ± 3.0),( 16.7 ±3.4) and serum immunoglobulin (5.1 ±0.6),(6.2 ± 1.0),(6.1 ± 1.0) were significantly higher than control group,the difference was statistically significant ( t =18.4,11.6,9.2,5.4,8.1,7.3,all P < 0.05 ).ConclusionThe variation of T lymphocyte subsets and serum immunoglobulin for perioperative patients with thyroid cancer was regular,and could be used as one of the indicators to determine for tumor recurrence or metastasis.
6.Pharmacokinetics of Glutathione by IV in Beagle Dogs
China Pharmacy 2007;0(25):-
OBJECTIVE:To investigate pharmacokinetic parameters of glutathione( GSH )after intraveneous injection(iv) in dogs. METHODS: A single dose of 40 mg?kg-1 was given to 12 Beagle dogs by iv,their plasma blood sample in different times were collected and concentrations of GSH were detected by HPLC,then the pharmacokinetic parameters were calculated using 3p97 software program. RESULTS: The concentration-time curves of GSH with iv fitted to two-conpartment model. The main pharmacokinetic parameters including t1/2?、t1/2?、V(c)、CL(s)、AUC0~t were(2.32?1.26) min,(16.03?6.58) min,(1.13?0.54) L?kg-1,(0.080?0.027) L?min-1 and (546.69?189.45) ?g?h?mL-1,respectively. CONCLUSION: GSH in circulatory system of dogs after iv has short retention time and quick elimination.
7.On Improving Healthcare Service under the Background of New Healthcare Reform
Chinese Medical Ethics 1994;0(06):-
The new healthcare reform project raised the thought that basic medical care service should be available to each individual,and the objective of an entire-people covered medical care assurance,which provide policy guarantee for the improvement of medical care service.To achieve the real advancement of medical care service,many endeavors are involved as follows.It is necessary to strengthen the responsibility share of all-level governments,guarantee the input for medical care adapted to local conditions and meanwhile embody medical care impartiality,strengthen the quality construction within medical care institutions,develop the role of medical care service in directing the patients triage which guides residents to get access to community medical centers,and respect individual's own choice for medical care so as to achieve the competition mechanism among medical care service designated hospitals.
8.Observations on the Efficacy of Triple Method of Heat-sensitive Point Moibustion and Taiji Acupuncture plus Massotherapy in Treating Facial Spasm
Shanghai Journal of Acupuncture and Moxibustion 2016;35(3):284-286
Objective To investigate the clinical efficacy of triple method of heat-sensitive point moibustion and Taiji acupuncture plus massotherapy in treating facial spasm.Method Sixty patients with facial spasm were randomly allocated to treatment and control groups, 30 cases each. The treatment group received triple method of heat-sensitive point moibustion and Taiji acupuncture plus massotherapy and the control group, conventional acupuncture plus suspended moxibustion with moxa stick. After three courses of treatment, the clinical therapeutic effects on spasm (severity and frequency) were compared between the two groups. Result The total efficacy rate and the cure and marked efficacy rate for spasm (severity) were 86.7% and 43.3%, respectively, in the treatment group and 66.7% and 26.7%, respectively, in the control group; there were statistically significant differences between the two groups (P<0.01). The total efficacy rate and the cure and marked efficacy rate for spasm (frequency) were 83.3% and 46.7%, respectively, in the treatment group and 66.7% and 30.3%, respectively, in the control group; there were statistically significant differences between the two groups (P<0.01).Conclusion Triple method of heat-sensitive point moibustion and Taiji acupuncture plus massotherapy is an effective way to treat facial spasm.
9.Effect of Transcutaneous Electrical Stimulation on Jiaji Acupoint on Expression of Glial Fibrillary Acidic Protein and Inflammation in Rats after Spinal Cord Injury
Chinese Journal of Rehabilitation Theory and Practice 2016;22(6):660-666
Objective To observe the effect of transcutaneous electrical stimulationon on Jiaji acupoint (Ex-B 05) on the expression of glial fibrillary acidic protein (GFAP), nuclear factor kappa B (NF-κB) and interleukin-6 (IL-6) in rats with spinal cord injury (SCI). Meth-ods Ninety healthy adult Sprague-Dawley rats were randomly divided into normal group (group A, n=30), transcutaneous electrical stimula-tion treatment group (group B, n=30) and control group (group C, n=30). Allen's method was used to establish the model of acute SCI in T9. All of them were assessed with Basso-Beattie-Bresnahan (BBB) scale and Slanting Board Test, and the expression of GFAP, NF-κB and IL-6 of the spinal cord were detected with immunohistochemistry one, three and seven days after operation. Results The results of BBB scale and Slanting Board Test were better in group B than in group C three and seven days after SCI (t>3.349, P<0.01). The expression of GFAP, NF-κB and IL-6 was lower in group B than in group C at all the time points after SCI (t>20.815, P<0.001). Conclusion Transcutane-ous electrical stimulation can inhibit the inflammation and the expression of GFAP in spinal cord after SCI, and improve the motor function in rats after SCI.
10.Study and analysis on stressors of undergraduate nursing students in the grade A hospitals
Chinese Journal of Practical Nursing 2016;32(17):1343-1346
Objective To investigate and analyze the characteristics of stressor that the undergraduate nursing students have to face at the clinical work in grade A hospitals , then to provide the scientific basis for clinical teaching management and reduce the pressures of undergraduate nursing students. Methods Questionnaires werehanded outto 80 undergraduate nursing students and datawere collected in the condition of their consents. Results The undergraduate nursing students had the higher scores on the dimensions of Patient Care and Nursing Work and stayed the pressure above average. Male and female undergraduate nursing students had the different top 5 stressors, the difference was statistical significance (t=2.434-3.644, P < 0.05). Conclusions The clinical teaching should care for the different stressors of male and female to reduce work and psychological pressure by taking effective measures, and give more attention to strengthen capacity-building of professional practice.