1.Significance of establishing a corpus of English translation for the TCM health preservation
Chunli LU ; Lilan DU ; Zhufen CHEN
International Journal of Traditional Chinese Medicine 2017;39(1):63-67
This paper discussed and elucidated the significance of establishing a corpus of English translation for the TCM terms of health preservation. To investigate the necessity and feasibility of corpus, we have explored the domestic and international researchs of the data sources and corpora and translation of TCM terms. We also predicted the prospect of application of this corpus.
2.Effects of pyrrolidine dithiocarbamate on aquaporin-9 expression and brain edema around the hematoma in experimental intracerebral hemorrhage
Min CHEN ; Changqing LI ; Chunli WU
Journal of Clinical Neurology 1997;0(06):-
Objective To investigate the effects of pyrrolidine dithiocarbamate(PDTC) on aquaporin-9(AQP9) expression and brain edema around the hematoma in experimental intracerebral hemorrhage(ICH).Methods 128 SD rats were randomly divided into four groups: normal group,control group,ICH group and PDTC group.According to Rosenberg's methods,the models of experimental ICH were established.The rats in PDTC group were received PDTC intraperitoneally 2 h later.The brain weight column(BWC) at different time point was calculated by gray-wet method,and the expression of AQP9 was examined by immunohistochemistry.Results The BWC and expression of AQP9 in hematoma side of ICH begin to increase 4 h after ICH,peaked at 72 h,and decreased 120 h later.The BWC in opposite side of hematoma also increased 4 h after ICH and peaked at 72 h.Compared with control group,the BWC and expression of AQP9 in ICH group were higher,especially in hematoma side of brain(all(P
3.The cough reflex sensitivity and airway neurogenic inflammation in patients with cough post infectious
Ruchong CHEN ; Chunli LIU ; Wei LUO
Chinese Journal of Practical Internal Medicine 2001;0(09):-
Objective To investigate the role of the cough reflex sensitivity and airway neurogenic inflammation in the pathogenesis of cough post infectious(CPI).Methods Capsaicin provocation test and sputum inducing were performed in 10 patients with CPI(CPI group)and 10 healthy subjects(normal control group)to detect the cough reflex sensitivity and neurokinin of sputum.Total and differential cells count of induced sputum was performed.Substance P(SP),neurokinin A(NKA),neurokinin B(NKB)and calcitonin gene-related peptide(CGRP)in the supernatant of induced sputum were measured.The expression of SP,neurokinin 1 receptor and NKA in sputum cells was detected.Results The cough threshold(lg C5)of CPI was significantly lower than normal(1.16?0.61 vs 2.64?0.28,P
4.Protective Effects of Polysaccharide of Membranous Milkvetch (Astragalus membranaceus) on Acute Myocardially Infarcted Heart in Dog and Its Machanism of Action
Wenwei LU ; Chunli LEI ; Yu CHEN
Chinese Traditional and Herbal Drugs 1994;0(11):-
Seventeen physiological,biochemicaland morphological indexes consistently showed that Astragalus polysaccharide was able to enhance the myocardia contractility,attenuate the area of myocardial infarction, and reduce the degree of myocardial damage of myocardially infarcted dog heart in vivo.The mechanism might be related to the inhibition of Na+-Kr+ATPase activity & the anti-free-radical-damage action.
5.Research progress of Babesia rhoptry associated proteins
Chunli YANG ; Yuchun CAI ; Jiaxu CHEN
Chinese Journal of Schistosomiasis Control 2017;29(2):252-256
Babesia parasites are obligate intracellular apicomplexan protozoa and important pathogens causing babesiosis of humans and animals. They have conserved subcellular structures and invasion mechanism. Rhoptry⁃associated proteins,which are released into the host cell,are considered to be the key molecules of invasion and replication of parasites in the host cell and are immunosuppressive factors of the host cell mediated immunity in the stage of parasitophorous vacuole(PV)formation. The knowledge about rhoptry⁃associated proteins has made a great progress with the development of genomics and proteomics,so we review the research progress in rhoptry⁃associated proteins of different Babesia including Babesia bovis,B. ovine,B. gibsoni,B. bigemina and B. orientalis,etc.
6.BOLD-fMRI Study of Auditory Cortex in Patients with Sensorineural Hearing Loss
Xianming CHEN ; Chunli MAO ; Ziqian CHEN ; Youqiang YE ; Ping LUO
Journal of Audiology and Speech Pathology 2009;17(3):227-230
Objective BOLD-fMRI was used to observe the activated auditory cortex evoked by pure tone stimuli in patients with sensorineural hearing loss and this paper is to discuss the objective measure for patient with sensorineural hearing toss. Methods BOLD-fMRI examinations were taken in 22 patients with unilateral moderate to severe sensorneural hearing loss and 15 control subjects. The volumes and intensities of the two hemispheres of the activated auditory cortex were analyzed quantitatively. Results Significant activation was found in the temporal lobe in control subjects, and significant differences in the volume and intensity were noted between the contralateral and ipsilateral activated auditory cortexes in them (P<0.01), exhibiting clearly eontralateral predominance. When the normal ear of patients with sensorineural hearing loss received signals, there was no significant difference be-tween contralateral and ipsilateral activated auditory cortexes (P>0.05). Conclusion When the normal ear of pa-tients with sensorneural hearing loss was stimulated by pure tone, the contralateral hemisphere predominance disap-peared. This result seems to show the plasticity of auditory cortex of patients with unilateral hearing loss.
7.Application of dynamic vascular patterns in differential diagnosis of focal liver lesions in contrast-enhanced ultrasound
Chunli ZHANG ; Wenwei CHEN ; Gang BAI ; Liao CHEN ; Hui HUANG
Chinese Journal of Ultrasonography 2013;(3):226-230
Objective To explore the application value of dynamic vascular patterns(DVP) curve and parameter figure in the focal liver lesions by contrast-enhanced ultrasound(CEUS).Methods 83 cases of focal liver lesions diagnosed by pathologically or clinically that had undergone CEUS were analyzed by SonoLiver software.Then DVP parametric images were constructed and the time-intensity curve (TIC) parameters were calculated by TIC and DVP curve.Results Rise time(RT),time to peak(TTP),maximum intensity(IMAX),mean transit (mTT),slope of rise,and the absolute value for slope of half down between malignant and benign lesions groups indicated statistically significant difference (P <0.05).94.9% of type Ⅰ was malignant lesions and 100% Ⅳ type was benign lesions.The four types of DVP curve(Ⅰ,Ⅱ,Ⅲ,Ⅳ)in malignant and benign lesions were 72.5%,13.7%,13.7%,0 and 6.2%,43.8%,31.2%,18.8%,respectively.The proportion and characteristic of DVP parametric images and DVP curves in malignant and benign lesions groups were consistent.Conclusions DVP curve and parametric images of CEUS can demonstrate the difference of flow perfusion static between lesions area and surrounding liver parenchyma dynamically and directly.These are new qualitative indexes of the differential diagnosis in focal liver lesions.
8.Prevention of fibrous capsule contracture using triamcinolone combined with vitamin E following silica gel prosthesis implantation
Ning LI ; Feng LI ; Yanwei CHEN ; Gangyi CHI ; Chunli QIN
Chinese Journal of Tissue Engineering Research 2009;13(38):7523-7527
OBJECTIVE: To observe the effect of triamcinolone combined with vitamin E on preventing fibrous capsule contracture following the second breast augmentation. METHODS: Totally 65 patients who had 130 breasts receiving the second breast augmentation at the Department of Plastic and Aesthetic Surgery, No.1 People's Hospital of Nanning were collected and served as the treatment group, including 47 cases with capsules contracture and 18 cases with hydrogel clearing. Tri-Kort was injected after the second breasts augmentation, and vitamin E was taken orally for 3 months. Additional 65 cases with 130 breasts received the second breast augmentation were served as control group. The follow-up was performed after half month, and the curative effect was evaluated by Baker grading at 1 year after operation. RESULTS: All cases in the two groups were received 6-24 months follow-up. Only 3 cases (5 breasts) in 65 patients (130 breasts) in the treatment group had capsule contracture (Baker II-III), with 3.8% of capsule contracture, which was obviously less than 18% of capsule contracture in the control group (P < 0.01,13 cases with 23 breasts in the control group). Simultaneously, no drug adverse reaction occurred in the treatment group. CONCLUSION: Triamcinolone combined with vitamin E can obviously depress the rate of capsule contracture after the second breast implantation.
9.Angiogenic effect of basic fibroblast growth factor on anterior cruciate ligament reconstruction with freeze-dried tendon implants at early stage: A histological observation
Chunli ZHANG ; Hu XU ; Hongbin FAN ; Jiapeng ZHENG ; Rongbo CHEN
Chinese Journal of Tissue Engineering Research 2008;12(53):10425-10429
BACKGROUND: Based on previous studies, the combination of basic fibroblast growth factor (bFGF) with graft may accelerate the procedure of vascular invasion of anterior cruciate ligament (ACL) graft. The antigenicity of graft could be inhibited by the destruction of major histolocompatibility complex (MHC) through the treatment of allogenous tendon by freeze. The freeze. dried tendon showed advantages including prolonged storage time. availability for transport and possibility of commercial application. There is no experimental and clinical study on the graft substance of bFGF combined tendon in ACL reconstruction in animal model so far. OBJECTIVE: To observe histologically the effect of exogenous application or bFGF combined to freeze-dried tendon on angiogenic enhancement in early ACL reconstruction. DESIGN, TIME AND SETTING: Controlled animal study, which was performed in the Department of Orthopeadics, Xijing Hospital. Fourth Military Medical University of Chinese PLA between June 2006 and June 2007.MATERIALS: Fourteen dogs were used in the experiment. METHODS: Extensor digitorum longus tendon was harvested from the rest 2 dogs and treated by freeze-dry as graft for other experimental dogs. bFGF(100 u g/L)was combined to freeze-dried tendon and then transplanted into one side knee to substitute the original ACL. While only freeze-dried tendon was used in the transplantation at the other side as control. MAIN OUTCOME MEASURES: Twelve of them were randomly divided into 6 groups according to the 6 time points,i,e.,1,2,3,4,5,6 weeks after surgery(2 dogs in each group).The histological observation with HE staining was done under microscope to mainly observe the angiogenesis in the transplanted ACL. RESULTS: Neovascularization occurred at the 2nd to 3rd weeks and reached the peak at the 4th to 5th weeks postoperatively at the experimental sides. By contrast. The neovascularization occurred at the 4th to 5th weeks postoperatively at the control sides. Neovascularization in the combined group was longer and deeper than that in the control group. CONCLUSION: The time of neovascular formation and the depth of vascular penetration into the tendon in the group of bFGF combined to freeze-dried tendon are superior to those in the control group.
10.Clinical efficacy of Sky Bone Expander System in the treatment of osteoporotic vertebral body compression fractures in the elderly
Zhijian ZHAO ; Kunfeng CHEN ; Wei MEI ; Chunli WANG
Clinical Medicine of China 2012;28(11):1208-1209
Objective To investigate the therapeutic effect of Sky Bone Expander System in the treatment of osteoporotic vertebral body compression fractures in the elderly.MethodsTwenty-five cases (26 vertabrals)with osteoporotic vertebral body compression fractures were treated by Sky Bone Expander System.ResultsAll the 25 cases completed the surgery successfully,with an average operation duration of 35 min (range:30 -60 min).We injected 2.7 -4.5 ml bone cement to each vertebrae with an average of 3.5 ml.No blood vessels and nerves damage or other complications were found.The height of vertebral was restored.ConclusionSky Bone Expander System could effectively treat osteoporotic vertebral body compression fractures in the elderly.The height of vertebral could rebound and kyphosis could be improved.Furthermore,Sky Bone Expander System could relieve pain and reduce the leakage of bone cement