1.Comparison of the application of NRS2002 and MNA in nutritional assessment of patients with primary liver cancer
Chinese Journal of Practical Nursing 2014;30(11):44-46
Objective To explore the nutritional condition of primary liver cancer inpatients by means of nutrition risk screening 2002 (NRS2002) and mini nutritional assessment,and compare their feasibility.Methods A total of 80 cases of liver cancer patients hospitalized in Tianjin Third Central Hospital from August 2012 to March 2013 were collected.We investigated the incidence of malnutrition with the scales of NRS2002 and MNA.Comparative analysis of the relationship between the two methods and the traditional single index,liver function was conducted in order to find the more appropriate one for nutritional evaluation.Results NRS2002 got a 33.7% nutrition risk incidence and MNA showed a 45.0% risk rate.NRS2002 showed better correlation with traditional individual indicators than MNA.Conclusions Compared with MNA,NRS2002 is more reliable for nutritional assessment in primary liver cancer inpatients.
2.Research progress on anti-tumor effects and potential mechanisms of ethyl pyruvate
Journal of Medical Postgraduates 2014;(10):1111-1113
Ethyl pyruvate ( EP) is a stable lipophilic ester derivative of pyruvate with many pharmacological actions confirmed by researches , the anti-tumor effects of EP has attracted the attention of many domestic and foreign scholars .EP exerts antitumor activi-ty through several ways , such as inhibiting proliferation , inducing apoptosis , inhibiting angiogenesis , blocking cell cycle .This paper briefly reviews the rencent findings of antitumor function of EP .
3.The effects on morphology of middle turbinate and olfaction after endoscopic sinus surgery and conventional technique in sinus surgery
Chunhua XU ; Yan ZHONG ; Ruohui SONG
Chinese Archives of Otolaryngology-Head and Neck Surgery 2001;8(2):71-75
Objective: To observe the effects on morphology of middle turbinate and olfaction in trasnasal endoscopic sinus surgery and conventional technique in surgery in chronic sinusitis and nasal polyps (stage Ⅰ,Ⅱ)。 Methods: Two groups patients (85 cases, 163 sites) from September 1979 to September 1999 were examined by coronal CT scans of sinus, nasal endoscopy and olfctory test preoperative and postoperative. Of these patients, 52 cases (101 sites) were operated by transnasal endoscopic sinus surgery, 33 cases (62 sites) were operated by conventional technique in surgery respectively. Management of middle turbinate was divided into reserving and resecting two way. Results: In group of endoscopic sinus surgeries (52 cases, 101 sites), the rates of cure, improved and ineffective were 64.4% (65/101), 29.7%(30/101), 5.9%(6/101) respectively by following 6 months; and returning to normal rates of middle turbinate were 63.1% (41/65), 30.0% (9/30), 0.0% (0/6) respectively; and the returning to normal rates of olfaction were 66.2% (43/65), 36.7% (11/30),0.0%(0/6) respectively; the returning to normal of middle turbinate were 47.4%( 9/19),3.3%(1/13),0.0%(0/13) respectively; the returning to mormal rates of olfaction were 63.2%(12/19),23.3%(7/30),0.0%(0/13) respectively.Conclusion: Endoscopic sinus surgery for chronic sinusitis and nasal polyps can solve ostiomeatal complex anomalism more effectively and raise the cure rates of sinusitis (stage Ⅰ,Ⅱ) than conventional technique in surgery. The morphology middle turbinate and olfaction returned to normal affected directly sinusitis curative rate.
4.Preparation and antibacteria activity of crude mutacin from clinical isolate of Mutans streptococci
Song LI ; Tianjia LIU ; Chunhua FU
Journal of Practical Stomatology 1995;0(04):-
Objective:To obtain crude mutacin produced by clinical isolate of Mutans streptococci (Ms) and to test its antibacteria activity. Methods:The mutacin in supernatant of in vitro cultured clinical isolate of Ms was extracted by chloroform, the antibacteria activity and heat stability of the crude extract were tested by bacteria culture technique. Results:Crude extract of protein was obtained fom clinical isolate of Ms. 10 ml of the liquid extract produced a 19 mm inhibitory zone in cultrue dish, indicating its antibacteria activity. The activity could maintain in 80 ℃ for 120 min, indicating its heat stability. Conclusion: The crude extract can represent the antibacteria activity and heat stability of mutacin.
5.Optimizing the Inclusion Process of Volatile Oil in Biyuanling Granules through Orthogonal Experiment
Chunhua LI ; Qing LI ; Xiaoyu SONG
China Pharmacy 1991;0(03):-
OBJECTIVE:To optimize?-cyclodextrin inclusion process in the inclusion of volatile oil compounds of peppermint,biond magnolia flower and agastache rugosa in biyuanling granules.METHODS:Orthogonal experiment was performed,the inclusion process was evaluated with inclusion rate of volatile oil,recovery rate of inclusion compound,extract ratio of inclusion compound as indexes.RESULTS:The optimized inclusion condition was as follows,the ratio of volatile oil to?-cyclodextrin was1∶8(ml/g)with10min ultrasound time and20℃ultrasound water temperature.CONCLUSIONS:The optimized method was simple and efficient,and suitable for industrialized production.
6.Influence of three primers on the shear bond strength between cast titanium and composite resin.
Jie LIU ; Hao WU ; Fanyu MENG ; Chunhua SONG
West China Journal of Stomatology 2014;32(3):225-228
OBJECTIVETo investigate the influence of three primers on the shear bond strength between cast titanium (Ti) and composite resin.
METHODSThe disks (n = 40) were cast by commercially pure (CP) Ti, which diameter were 8 mm and thick were 3 mm. The titanium surfaces were polished with silicon carbide sand papers under running water and then treated by sandblasting and acid (4%HF) etching. They were divided into four groups: control group (group A), treated with KH-570 (group B), treated with Alloy Primer (group C), treated with Metal photo primer (group D). After treatment, the specimens were evaluated for their shear bond strengths by universal testing machine. The values were statistically analyzed. The fractured surfaces were observed by scanning electron microscope (SEM).
RESULTSThe shear bond strengths of group A, B, C, D were (9.773 +/- 0.67), (11.463 +/- 0.82), (14.224 +/- 0.75), (13.157 +/- 0.73) MPa. There were significant differences in bond strength between A and B, C, D (P < 0.01). B and C, D had significant differences (P < 0.01). C and D had no significant differences (P>0.05).
CONCLUSIONKH-570, Alloy Primer, Metal photo primer significantly improve the bond strength of ceramage composite resin to cast titanium. KH-570 group bonding strength is lower than the the Alloy Primer group and Metal photo primer group.
Composite Resins ; Dental Bonding ; Materials Testing ; Methacrylates ; Shear Strength ; Silanes ; Silicates ; Thiones ; Titanium
7.Immunological adaptive response induced by low dose X-rays
Guizhi JU ; Xu SU ; Chunhua SONG ; Shuzheng LIU
Journal of Jilin University(Medicine Edition) 1999;25(5):559-563
Objective: To find out whether or not low dose radiation could induce resistance to challenge dose-induced depression of immune functions.Methods:The following techniques were employed in this experiment:flow cytometry with immunofluorescence for the expression of TCR/CD3 receptor,3H-TdR incorporation technique for the spontaneous proliferation of thymocytes and the mitogen-induced proliferation of splencoytes as well as a bioassay with CTLL cells for IL-2 production.Results:The following optimal conditions for the induction of immunological adaptive response were determined:0.025 to 0.1 Gy for the conditioning doses (D1),1.0 to 1.5 Gy for the challenge doses (D2),and 6 to 12 h for the intervals between D1 and D2.Conclusion:Immunological adaptive response could be induced by low dose radiation.
8.Serological survey of encephalomyocarditis virus infection in swine in Hebei Province
Lanya LIU ; Chunhua CHEN ; Yujing XU ; Qinye SONG ; Tanqing LI
Chinese Journal of Zoonoses 2010;(3):252-254
In order to survey the prevalence of encephalomyocarditis virus (EMCV) infection in pigs in Hebei Province from 2006 to 2008,a total of 1306 swine serum from 31 farms in 10 regions in Hebei were tested for antibodies against EMCV nonstructural protein 2C by ELISA.Positive rates of antibodies in different regions and different age groups were analyzed.The results showed that antibodies against EMCV 2C were found in 176 out of 1306 serum samples collected from Hebei Province and the total positive rate was 13.48%.Seroprevalence of EMCV infection appeared in six out of ten surveyed regions and the highest positive rate was 26%.There was significant difference of seroprevalence in EMCV infection between breeder sows and other swine species.This survey indicated that EMCV infection has occurred in pig farms in most regions of Hebei Province and EMCV-carried breeder sows were one of the crucial causes for EMCV infection and prevalence.
9.Deficit of social cognition with patients following the temporal lobes infarction
Nan TANG ; Youling ZHU ; Chunhua XI ; Wei CAI ; Daohui SONG
Chinese Journal of Neurology 2013;(6):379-382
Objective To investigate the ability of social cognition in patients with right temporal lobe infarction.Methods Fifteen patients with temporal lobe infarction (TLI) and 20 healthy controls (HC) were examined with the recognition of faux pas and reading the mind in the eyes tasks for assessing the ability of social cognition.Results The TLI group performed significantly worse when compared with the HC group (28.6 ± 6.1,36.4 ± 4.3 respectively) as revealed in the total faux pas-related scores (U =41.00,P <0.01).For the control question,there was no significant difference between the TLI group and the HC group (9.86 ±0.35,10.00 ± 0.00 ; U =130.00,P =0.097).In the reading the mind in the eyes task,patients with TLI performed worse than the HC group(17.13 ±6.41,29.75 ±2.07 respectively),and the difference had statistical significance (U =0.00,P < 0.01).But there was no significant difference in gender recognition judgment (30.37 ± 1.16,31.35 ± 1.08 respectively; U =106.00,P =0.129).Conclusions The right temporal lobe involves in social cognition.Moreover,the right temporal lobe not only involves in the verbal related social cognitive processing,but also involves in the no-verbal related social cognitive processing.
10.Effects of different doses of dexmedetomidine on cerebral oxygen saturation and pulmonary shunt fraction in patients undergoing one-lung ventilation
Yun MENG ; Hua ZHANG ; Zhiqun XIA ; Yonghao YU ; Chunhua SONG
Tianjin Medical Journal 2016;44(5):602-604
Objective To investigate the effects of different doses of dexmedetomidine on cerebral oxygen saturation and pulmonary shunt fraction in patients undergoing one-lung ventilation (OLV). Methods Sixty ASAⅠ-Ⅱpatients, aged 46-71 years, with body mass index (BMI)18-24 kg/m2 and scheduled for thoracotomy were randomly divided into three groups (n=20 each):high dose dexmedetomidine group (group D1), low dose dexmedetomidine group (group D2) and control group (group C). Dexmedetomidine 1μg/kg was infused in group D1 after anesthesia induction, and then a rate of 0.5μg·kg-1·h-1 was continuously infused. Dexmedetomidine 0.5μg/kg was infused in group D2 after anesthesia induction, and then a rate of 0.3μg · kg-1 · h-1 was continuously infused. Group C was received the equal volume of normal saline. Anesthesia was main?tained with propofol-remifentanil and intermittent iv boluses of rocuronium. Arterial and jugular venous blood samples were collected before anesthesia induction (T0), at 15 min after two-lung ventilation (T1), at 5 min (T2) and 30 min (T3) of OLV for blood gas analysis. Value of Qs/Qt was calculated and SctO2 was recorded at the same time. Results Compared with group C and group D2, Qs/Qt was decreased at T2 in group D1 (P<0.05). Qs/Qt was lower at T3 in group D1 and D2 than that of group C, and which was lower in group D1 than that of group D2 (P<0.05). In group C and group D1 a significant de?crease in SctO2 was observed at T2 and T3 compared to that at T0 and T1 (P<0.05). SctO2 was significantly higher at T2 and T3 in group D2 than that in group C and group D1 (P<0.05). Conclusion Dexmedetomidine given during OLV undergoing thoracotomy can improve oxygenation, decrease pulmonary shunt fraction and reduce the occurrence of low SctO2.