1.Losartan in the Treatment of Essential Hypertension
Chinese Journal of Pharmacoepidemiology 2001;10(1):6-7
To investigate the efficacy and safety of losartan in the treatment of essential hypertension, 81 patients were randomly assigned to two groups. Patients in the first group(n =41) were given losartan 50 mg to 100 mg once a day; those in the second group( n = 40) were given benazepril 10 mg to 20 mg once a day. The treatment course lasted for a weeks. Ambulatory blood pressure, hepatic and renal functions, blood glucose were examined before and after therapy. Our results showed that the total efficacy rate in losartan group was 93% while that in benazepril group was 90%. The efficacy was similar between the two groups. However, effect of 24 h blood pressure control by lossrtan was superior to than of benazepril. The adverse reaction of losartan was milder that that of benazepril. It is concluded that losartan is a safe, long-acting antihypertensive agent for mild and moderate hypertension with good patient tolerance and less adverse reactions.
2.Prolapse of Fallopian Tube into Vaginal Vault after Hysterectomy: A case report.
Korean Journal of Pathology 1998;32(6):474-475
The prolapse of a fallopian tube into the vagina is a rare complication of hysterectomy. We recently experienced a case of tubal prolapse after a laparoscopic hysterectomy in a 44-year-old woman. The vaginal examination showed a polypoid mass in the vaginal apex. Microscopically, the mass had the typical appearance of a fallopian tube with chronic inflammation. The cytologic finding of a vaginal vault smear was also described.
Adult
;
Fallopian Tubes*
;
Female
;
Gynecological Examination
;
Humans
;
Hysterectomy*
;
Inflammation
;
Prolapse*
;
Vagina
5.Surgical Intervention Combined with Steroid Therapy on Persistent Jaundice in Infantile Hepatitis
Journal of Applied Clinical Pediatrics 2006;0(20):-
Objective To investigate the effect of surgical intervention combined with steroid therapy on infantile hepatitis(INS) with persistent jaundice.Methods Twenty-two patients (19 males,3 females,aged 2-6 months) with persistent jaundice(therapy group) were admitted into hospital in the period of Jan.2007-Dec.2008.The patients were performed with surgical intervention after they were confirmed with diagnosis as INS.Then,sodium chloride,gentamicin and Dexamethasone were used to irrigate the biliary tract during and after the operation for 14 days.Three days after operation,20 mg,15 mg,10 mg,5 mg of methylprednisolone were administered intravenously to the patients every 3 days,followed with 4 mg/(kg?d) prednisone by oral for 2-3 months.The 17 cases of INS with persistent jaundice were treated with medicine as control(control group).By following-up,the jaundice free and 2 years survival rate of 2 groups were compared by counting the cases of jaundice free and recording the survival time.Results Two cases of 22 patients performed with surgical intervention were diagnosed as biliary atresia and others were INS,90.0% patients were free of jaundice in surgical intervention combined with steroid therapy group,which was higher than that in control group(52.9%,P
6.The role of psychological stress and the hypothalamic pituitary adrenal axis in the pathophysiology of central serous chorioretinopathy
International Eye Science 2009;9(5):809-811
Central serous chorioretinopathy (CSC) is characterized by serous detachment of the sensory retina as a consequence of the focal leakage of fluid from the choriocapillaries to subretinal space through a defect of the retinal pigment epithelium(RPE). The exact cause of CSC is not well unknown. Psychological stress is thought to contribute to CSC, but the physiologic mechanisms are unclear. It is hypothesized that psychological stress can induce CSC through the mechanism of the hypothalamic-pituitary-adrenal (HPA) system. Psychological stress can adversely affect HPA axis and causes glucocorticoid levels to elevate. Increased glucocorticoids constrict choroid vessels, which leads to ischemia of choroids and damage vascular endothelial cells, thus causing vasopermeability to increase. RPE dysfunction will occur as a result of abnormalities in the choroidal circulation. The large molecules including protein may enter the subretinal space through the damaged vessels and RPE.
7.A case of pulmonary artery ectasia misdiagnosed as stage III coal worker's pneumoconiosis.
Liang CHEN ; Yi LI ; Chun-xiao YU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(9):576-557
Anthracosis
;
diagnosis
;
Diagnostic Errors
;
Humans
;
Lung Diseases
;
diagnosis
;
Male
;
Middle Aged
;
Pulmonary Artery
10.Ultrasonic Diagnosis in Upper Extremity Deep Venous Flow Obstruction and Superior Vena Cava Syndrome
Fang YI ; Xinhuan GONG ; Chun ZHOU
Chinese Journal of Medical Imaging Technology 2001;17(5):470-471
Objective To explore the pathogeny, pathology, ultrasonic and clinical expression of upper extremity deep venous flow obstruction and superior vena cava syndrome. Methods Retrospective analysis and summarize the disease changes of 10 cases in recent 5 years. Results 7 patients of 10 cases were superior vena cava syndrome, in which 4 cases caused by upper right lung malignant tumor, 3 cases caused by upper and media mediastinal malignant tumor. 2 patients of 10 cases were found thrombosis in right subclavian vein caused by duct of artificial pacemaker. The left 1 patient was no reason thrombosis in right axillary vein. Conclusion Ultrasonography combine with color and spectral Dopper image can evaluate the clinical development and therapeutic efficiency, which is a useful and effective non-invasive examination.