1.Magnetic resonance imaging in the evaluation of cervical cancer
Journal of International Oncology 2014;41(6):450-454
Magnetic Resonance Imaging (MRI) can form a three-dimensional positioning anatomical imaging.By comparing the tumor volume and signal intensity changes,there is great value of MRI in the assessment of the efficacy of cervical cancer.With the development of imaging,magnetic resonance diffusion weighted imaging (DWI),magnetic resonance spectroscopy (MRS) can provide qualitative and quantitative information of the cellular level,which reflects changes in the treatment of tumor cells.Magnetic resonance imaging can predict early locally advanced cervical cancer neoadjuvant chemotherapy,thus providing an important basis for individualized treatment of patients.
2.Content Determination of Gentiopicroside in Xiaofeng Pills by RP-HPLC
China Pharmacy 2005;0(23):-
OBJECTIVE: To establish a RP-HPLC method for the content determination of gentiopicroside in Xiaofeng pills.METHODS: The chromatographic column was DiamonsiLTM C18(150 mm?4.6 mm,5 ?m) column with mobile phase consisted of acetonitrile-water(11 ∶ 89) at a flow rate of 1.0 mL?min-1.The detection wavelength was set at 254 nm.RESULTS: The linear range of gentiopicroside were 0.205 6~2.056 0 ?g (r=0.999 9) with an average recovery of 96.18%(RSD=1.55%,n=6).CONCLUSION: The method is simple,rapid and accurate for the quality control of Xiaofeng pills.
3.A case of restrictive cardiomyopathy.
Fu-yu PEI ; Chun-fu LI ; Yu-ming ZHANG
Chinese Journal of Pediatrics 2003;41(8):639-639
7.Constitution of lymphoid neoplasm in Xinjiang:analysis of 645 cases
Chun WANG ; Juanjuan FU ; Zhenzhu SUN
Chinese Journal of Clinical and Experimental Pathology 2014;(9):1021-1025
Purpose To study the pathologic types and subtypes distribution of 645 cases of lymphoma in Xinjiang. Methods Clini-cal data of lymphoma from April 2008 to march 2013 in the people’s hospital of Xinjiang Uygur autonomous region in Xinjiang were col-lected and reviewed, including morphological, immunohistochemical and clinical characteristics. According to the WHO classification all the cases were reappraised. Results Of the 645 cases, 558 cases (86.51%) were non-Hodgkin’s lymphoma (NHL) and 82 ca-ses (12.71%) were Hodgkin’s lymphoma (HL). Among NHL cases, 448 cases (80.29%) were B-cell neoplasms and 110 cases (19.71%) were T/NK-cell neoplasms. The commonest subtype was diffuse large B-cell lymphoma (258 cases, comprising 40% of all lymphomas) and extranodal NK/T-cell lymphoma (41 cases, comprising 6.36% of all lymphomas) in B cell lymphoma and T/NK cell lymphoma. Burkitt’s lymphoma and lymphoblastic leukemia/lymphoma were predominanly Uyghurs, but mantle cell lymphoma, follicu-lar lymphoma and extranodal marginal zone lymphoma of mucosa associated lymphoid tissue were predominanly Hans. The most com-mon subtypes of Hodgkin’s lymphoma are mixed cellularity, nodular sclerosis and lymphocyte-rich classical Hodgkin’s lymphoma. Sub-types distribution of Hodgkin’s lymphoma has a certain difference in the different ethnic groups, the age of onset did not present twin peaks and the highest proportion was children. Conclusion The lymphoid neoplasms of Xinjiang displayed some ethnic features simi-lar to those reported in literature as well as other regions of China, whereas the distribution of some subtypes showed some differences.
8.Expression of Protein Kinase B Isoforms in the Gastrocnemius Muscle of Rats at Different Ages
Bing ZHANG ; Chun XIA ; Fu CHEN
Chinese Journal of Minimally Invasive Surgery 2001;0(03):-
Objective To study the expression of protein kinase B (Akt/PKB) isoforms in the gastrocnemius muscle of rats at different ages. Methods The expression levels of mRNA and protein of three Akt isoforms in the gastrocnemius muscle of 30-month-old and 6-month-old rats were detected respectively by RT-PCR and Western blotting. Data were analyzed statistically. Results (1) The levels of Akt1 and Akt2 mRNA in the 30-month-old rats was significantly higher than those in the 6-month-old rats (t=7.124, P=0.000; t=2.598, P=0.021), however, no significant difference was found in the level of Akt3 mRNA between the two groups (t=0.460, P=0.653) . (2) The level of Akt-Thr308 phosphorylation in the 30-month-old rats was significantly lower than that in the 6-month-old rats (t=-9.861, P=0.000), while the level of Akt2 protein in the 30-month group was significantly higher than that in the younger rats (t=7.522, P=0.000). No significant differences were detected in the levels of Akt1 and Akt3 proteins between the two groups (t=0.469, P=0.646; t=0.058, P=0.955). Conclusion The expression levels of three Akt isoforms in the gastrocnemius muscle of rats change with age, suggesting that the three isoforms of Akt have different functions in the gastrocnemius muscle metabolism of rats at different ages.
9.Treatments for Multiple-Ligament Injury to the Knee
Chun XIA ; Shaojie WANG ; Ribin FU
Chinese Journal of Minimally Invasive Surgery 2005;0(08):-
Objective To study the diagnosis and treatment of multiple-ligament injury to the knee and report the clinical outcomes of the disease.Methods A total of 51 patients with multiple-ligament tear in the knee were enrolled in this study.The lesion involved the ACL and MCL in 21 cases,ACL and PLC in 1,PCL and MCL in 4,PCL and PLC in 6,ACL,PCL,and MCL in 6,ACL,PCL,and PLC in 3,ACL and PCL in 8,and PCL and patella tendon in 2.Among the patients,14 patients had acute Ⅲ grade MCL tear and 3 had acute Ⅲ grade PLC injury;open suture repair were performed on these cases,and then arthroscopic surgery was carried out for other injured ligaments after 3-week immobilization.For 2 patients who had chronic Ⅲ grade MCL injury and 3 cases that were suffering from chronic Ⅲ grade PLC tear,open surgery for ligament reconstruction was employed,arthroscopy were used afterwards to remodel the ACL and PCL.In the 51 patients,totally 39 ACLs were injured,20 of these ligaments were reconstructed under a arthroscope using Hamstring tendon,17 were repaired with BPB by arthroscopy,and 2 were remodelled by implanting allogeneic tendons.In addition,29 PCLs tear were diagnosed,among which arthroscopic PCL reconstruction with autologous Hamstring tendon was performed on 19,allogeneic ligaments were used in 2,and the other 8 injured PCL were not repaied surgically because the lesion was relieved after immobilization(improved from grade Ⅲ to
10.Analysis of the risk factors of myopia among different nationalities students in Karamay city
International Eye Science 2014;(7):1298-1302
AlM:To investigate the myopia risk factors of different nationalities students in primary and secondary schools in Karamay City.
METHODS:This survey was a cross-sectional design, the sample was selected in the first, third and sixth grade primary school and middle school students by stratified random cluster method. The survey team comprised of ophthalmologists, technicians, optometrists and administrative staff. The staff was trained about the design, method and quality control, etc. According to the research needs, questionnaires were designed. ln person interview, pilot study, questionnaire, intraocular pressure, corneal curvature, refraction, axial length, corneal thickness, slit lamp microscopy and fundus examination were performed. A database was established using the Epi-data software by double entry method. All statistical analysis was completed by SPSS 17. 0 software.
RESULTS:The survey covers 1 922 students in total, which account for 91. 4% students of the whole four grades. The total prevalence of myopia was 39. 2%. Multivariate analyses revealed that ethnic origin, age, gender, parents of short-sightedness, daily after-school reading and writing time and bad reading and writing habits were closely related to myopia ( OR=0. 149, 95%CI:0. 103-0. 216, P=0. 000; OR=1. 372, 95%CI: 1. 296-1. 453, P=0. 000; OR=1. 517, 95%CI: 1. 200-1. 918, P=0. 000;OR=0. 695, 95%CI: 0. 602-0. 804, P=0. 000; OR=1. 310, 95%CI:1. 086-1. 581, P=0. 005;OR=0. 655, 95%CI:0. 486-0. 882, P=0. 005).
CONCLUSlON: Ethnic origin, age, gender, parents of short - sightedness, daily after - school reading and writing time and reading and writing habits were independent risk factors for myopia.