1.Mobilization and collection of peripheral blood stem cells by using rhG-CSF in healthy donors
Lin WANG ; Keshan SHI ; Zhiming BAI ; Xiaoxia CHEN ; Zhiming WANG ; Xiansheng LUO ; Chumiao LIU ; Lili HE ; Qin WU ; Rongxiang FU ; Ziying HUANG ; Shumei HUANG ; Haimei HUANG ; Liqiong LI
Cancer Research and Clinic 2005;0(S1):-
Objective To analyse the effect of mobilization and collection's time of peripheral blood stem cells(PBSC) from 8 cases of healthy donors. Methods The 10 donors were studied by self-control design.The number of aphereses was two times every donors. Healthy donors received rhG-CSF according to two different PBSC collection starting time: group 1:PBSC collection was starts 2 hours(2 h) after the fourth day or the fifth day of rhG-CSF. group 2:PBSC collection was starts 4 hours(4 h) after the fourth day or the fifth day of rhG-CSF.(The first dose of rhG-CSF was given on day 1, considering day 0 as the day before starting mobilization). In this study we have compared with two groups of apheresis product. Results The MNC count was significantly higher for donors 4 h collection (groups 2) then 2 h. ( groups 1)(P
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