OBJECTIVE: To develop a set of consummated comprehensive application platform that meets the actual demand so as to promote hospital treatment level and pharmaceutical care quality.METHODS: The protocol and standard meeting the international standard was adopted for system design.The currently popular combination tools(Apache+PHP+MySQL) set was developed and an open information resources management system and multi-structured architecture were established.RESULTS & CONCLUSIONS: This system is practical,advanced and safe and it is composed of 5 modules: drug inquiry system,rational drug use system,management on adverse drug reactions,pharmacy administrative management and network management.The system can not only guarantee the compatibility and the expandability of system,but also meet the needs of the development of hospital pharmacy and effectively enhance the rational drug use.

The whole pharmaceutical care package was given by clinical pharmacist to a patient with infective endocarditis and renal insufficiency .The pharmacist performed pharmaceutical care by analyzing the condition of the patient ,evaluating and making treat-ment plan and adjusting the drug dosage .With the cooperation of clinical pharmacist ,the doctor optimized the treatment plan to individ-ualize treatment ,and ensured the effectiveness and safety of medications .

Objective: To understand the relationship between childhood abuse and social anxiety and its influencing factors,so as to provide a theoretical basis for the intervention targeting social anxiety in adolescents. Methods: The Metaanalysis was conducted on the 30 selected articles using randomeffects models, comprising 93 independent effect sizes and a total sample of 19 354. Odds ratio (OR) was used to integrate the relationship between childhood abuse and social anxiety. Results: There was a significant positive correlation between childhood abuse and social anxiety (r=0.22), and its subtypes (emotional abuse, emotional neglect, emotional maltreatment, physical abuse, physical neglect, sexual abuse) could also positively predict social anxiety (OR=3.14,1.97,2.42,1.78,1.68,1.54)(P<0.01). The moderating effect showed that cultural background could significantly moderate the relationship between emotional neglect and the composite index and social anxiety (Qb=3.95,3.93), and the relationship between emotional abuse and composite index and social anxiety were significantly moderated by age (Qb=7.65,8.72)(P<0.05). Conclusions Childhood abuse is a positive predictor of social anxiety. Cultural background and age have a significant moderating effect on the relationship between childhood abuse and social anxiety, but gender has no significant moderating effect.